Informal caregiving as a risk factor for type 2 diabetes in individuals with favourable and unfavourable psychosocial work environments: a longitudinal multi-cohort study
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Informal caregiving as a risk factor for type 2 diabetes in individuals with favourable and unfavourable psychosocial work environments : a longitudinal multi-cohort study. / Mortensen, Jesper; Clark, Alice Jessie; Lange, Theis; Andersen, Gregers Stig; Goldberg, Marcel; Ramlau-Hansen, Cecilia Høst; Head, Jenny; Kivimäki, Mika; Madsen, Ida Elisabeth Huitfeldt; Leineweber, Constanze; Lund, Rikke; Rugulies, Reiner; Zins, Marie; Westerlund, Hugo; Rod, Naja Hulvej.
In: Diabetes & Metabolism, Vol. 44, No. 1, 2018, p. 38-44.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Informal caregiving as a risk factor for type 2 diabetes in individuals with favourable and unfavourable psychosocial work environments
T2 - a longitudinal multi-cohort study
AU - Mortensen, Jesper
AU - Clark, Alice Jessie
AU - Lange, Theis
AU - Andersen, Gregers Stig
AU - Goldberg, Marcel
AU - Ramlau-Hansen, Cecilia Høst
AU - Head, Jenny
AU - Kivimäki, Mika
AU - Madsen, Ida Elisabeth Huitfeldt
AU - Leineweber, Constanze
AU - Lund, Rikke
AU - Rugulies, Reiner
AU - Zins, Marie
AU - Westerlund, Hugo
AU - Rod, Naja Hulvej
PY - 2018
Y1 - 2018
N2 - AimTo examine whether informal caregiving is associated with increased risk of type 2 diabetes (T2D), and whether job strain and social support at work modify the association.MethodsIndividual participant's data were pooled from three cohort studies—the French GAZEL study, the Swedish Longitudinal Occupational Survey of Health (SLOSH) and the British Whitehall II study—a total of 21,243 study subjects. Informal caregiving was defined as unpaid care for a closely related person. Job strain was assessed using the demand-control model, and questions on co-worker and supervisor support were combined in a measure of social support at work. Incident T2D was ascertained using registry-based, clinically assessed and self-reported data.ResultsA total of 1058 participants developed T2D during the up to 10 years of follow-up. Neither informal caregiving (OR: 1.09, 95% CI: 0.92–1.30) nor high job strain (OR: 1.04, 95% CI: 0.86–1.26) were associated with T2D risk, whereas low social support at work was a risk factor for T2D (OR: 1.18, 95% CI: 1.02–1.37). Also, informal caregivers who were also exposed to low social support at work were at higher risk of T2D (OR: 1.40, 95% CI: 1.08–1.82) compared with those who were not informal caregivers and had high social support at work (multiplicative test for interaction, P = 0.04; additive test for interaction, synergy index = 10).ConclusionInformal caregiving was not independently associated with T2D risk. However, low social support at work was a risk factor, and informal caregivers with low social support at work had even higher risks of T2D.
AB - AimTo examine whether informal caregiving is associated with increased risk of type 2 diabetes (T2D), and whether job strain and social support at work modify the association.MethodsIndividual participant's data were pooled from three cohort studies—the French GAZEL study, the Swedish Longitudinal Occupational Survey of Health (SLOSH) and the British Whitehall II study—a total of 21,243 study subjects. Informal caregiving was defined as unpaid care for a closely related person. Job strain was assessed using the demand-control model, and questions on co-worker and supervisor support were combined in a measure of social support at work. Incident T2D was ascertained using registry-based, clinically assessed and self-reported data.ResultsA total of 1058 participants developed T2D during the up to 10 years of follow-up. Neither informal caregiving (OR: 1.09, 95% CI: 0.92–1.30) nor high job strain (OR: 1.04, 95% CI: 0.86–1.26) were associated with T2D risk, whereas low social support at work was a risk factor for T2D (OR: 1.18, 95% CI: 1.02–1.37). Also, informal caregivers who were also exposed to low social support at work were at higher risk of T2D (OR: 1.40, 95% CI: 1.08–1.82) compared with those who were not informal caregivers and had high social support at work (multiplicative test for interaction, P = 0.04; additive test for interaction, synergy index = 10).ConclusionInformal caregiving was not independently associated with T2D risk. However, low social support at work was a risk factor, and informal caregivers with low social support at work had even higher risks of T2D.
U2 - 10.1016/j.diabet.2017.04.001
DO - 10.1016/j.diabet.2017.04.001
M3 - Journal article
C2 - 28527866
VL - 44
SP - 38
EP - 44
JO - Diabetes & Metabolism
JF - Diabetes & Metabolism
SN - 1262-3636
IS - 1
ER -
ID: 169731228