Physical and emotional well-being of survivors of childhood and young adult allo-SCT: A Danish national cohort study
Research output: Contribution to journal › Journal article › peer-review
The aim of this investigation was to examine, within a population-based study of a national cohort comprising Danish survivors of allo-SCT (n = 148), the long-term effects of allo-SCT in children and young adults. Physical and emotional well-being was assessed using the Short Form 36 (SF-36) and the HADS. Allo-SCT-related data were obtained from the participants' medical records. The study includes 148 patients, with an 89% response rate (n = 132). For comparison purposes, norm data from Danish (1994, n = 6000), Swedish (2006, n = 285), and British (2001, n = 1792) population samples were used. Factors negatively influencing the SF-36 subscales included female gender; TBI; stem cells derived from PB; older age at time of questioning; and living alone. Factors significantly (p < 0.05) influencing HADS were transplantation with stem cells derived from PB and being underweight at time of questioning (median values were within normal range). Overall scores of allo-SCT patients were similar to norm data. In conclusion, this national cohort study shows that patients treated with SCT in early life (<25) and whose survival period extended beyond 10 yr (mean) from SCT, showed similar levels of anxiety, depression, and physical and emotional well-being to those of the normal population.
Original language | English |
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Journal | Pediatric Transplantation |
Volume | 20 |
Issue number | 5 |
Pages (from-to) | 697-706 |
Number of pages | 10 |
ISSN | 1397-3142 |
DOIs | |
Publication status | Published - Aug 2016 |
- Journal Article
Research areas
ID: 166376687