Association of cold ambient temperature and cardiovascular markers

Research output: Contribution to journal › Journal article › peer-review

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Association of cold ambient temperature and cardiovascular markers. / Hong, Yun-Chul; Kim, Ho; Oh, Se-Young; Lim, Youn-Hee; Kim, So-Yeun; Yoon, Hyung-Jin; Park, Minseon.

In: The Science of the Total Environment, Vol. 435-436, 2012, p. 74-79.

Research output: Contribution to journal › Journal article › peer-review

Harvard

Hong, Y-C, Kim, H, Oh, S-Y, Lim, Y-H, Kim, S-Y, Yoon, H-J & Park, M 2012, 'Association of cold ambient temperature and cardiovascular markers', The Science of the Total Environment, vol. 435-436, pp. 74-79. https://doi.org/10.1016/j.scitotenv.2012.02.070

APA

Hong, Y-C., Kim, H., Oh, S-Y., Lim, Y-H., Kim, S-Y., Yoon, H-J., & Park, M. (2012). Association of cold ambient temperature and cardiovascular markers. The Science of the Total Environment, 435-436, 74-79. https://doi.org/10.1016/j.scitotenv.2012.02.070

Vancouver

Hong Y-C, Kim H, Oh S-Y, Lim Y-H, Kim S-Y, Yoon H-J et al. Association of cold ambient temperature and cardiovascular markers. The Science of the Total Environment. 2012;435-436:74-79. https://doi.org/10.1016/j.scitotenv.2012.02.070

Author

Hong, Yun-Chul ; Kim, Ho ; Oh, Se-Young ; Lim, Youn-Hee ; Kim, So-Yeun ; Yoon, Hyung-Jin ; Park, Minseon. / Association of cold ambient temperature and cardiovascular markers. In: The Science of the Total Environment. 2012 ; Vol. 435-436. pp. 74-79.

Bibtex

@article{8c2ed646caca4384823db9a4e6f8fa50,
title = "Association of cold ambient temperature and cardiovascular markers",
abstract = "Cardiovascular mortality has been shown to increase in the winter. However, it is unclear whether cold temperature affects indicators known as cardiovascular markers. We evaluated the association between ambient temperature and cardiovascular markers using data collected retrospectively from 55,567 adults who had visited a health check-up clinic between 1995 and 2008. Non-parametric smoothing regressions were fitted to determine the shapes of association between temperature and cardiovascular markers such as blood pressure, lipid profiles, platelet count, and high sensitivity C-reactive protein (hsCRP). Mixed effect model was used to investigate the significance of the relationship between temperature and cardiovascular markers. Decreased ambient temperature was associated with an increase in systolic and diastolic blood pressures, platelet count and serum low density lipoprotein-cholesterol concentration. In contrast, high density lipoprotein-cholesterol level declined with decreasing temperature. The hsCRP level increased with decreasing temperature in the minimum temperatures below 0°C, but revealed a reverse association above. Our study suggests that excess cardiovascular mortality in cold weather might be associated with temperature-related variations of cardiovascular markers.",
keywords = "Adult, Biomarkers/blood, Blood Pressure/physiology, C-Reactive Protein/analysis, Cardiovascular Diseases/blood, Cholesterol, HDL/blood, Cholesterol, LDL/blood, Cold Temperature, Female, Humans, Lipids/blood, Male, Middle Aged, Models, Biological, Platelet Count, Republic of Korea/epidemiology, Retrospective Studies",
author = "Yun-Chul Hong and Ho Kim and Se-Young Oh and Youn-Hee Lim and So-Yeun Kim and Hyung-Jin Yoon and Minseon Park",
note = "Copyright {\textcopyright} 2012 Elsevier B.V. All rights reserved.",
year = "2012",
doi = "10.1016/j.scitotenv.2012.02.070",
language = "English",
volume = "435-436",
pages = "74--79",
journal = "Science of the Total Environment",
issn = "0048-9697",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Association of cold ambient temperature and cardiovascular markers

AU - Hong, Yun-Chul

AU - Kim, Ho

AU - Oh, Se-Young

AU - Lim, Youn-Hee

AU - Kim, So-Yeun

AU - Yoon, Hyung-Jin

AU - Park, Minseon

N1 - Copyright © 2012 Elsevier B.V. All rights reserved.

PY - 2012

Y1 - 2012

N2 - Cardiovascular mortality has been shown to increase in the winter. However, it is unclear whether cold temperature affects indicators known as cardiovascular markers. We evaluated the association between ambient temperature and cardiovascular markers using data collected retrospectively from 55,567 adults who had visited a health check-up clinic between 1995 and 2008. Non-parametric smoothing regressions were fitted to determine the shapes of association between temperature and cardiovascular markers such as blood pressure, lipid profiles, platelet count, and high sensitivity C-reactive protein (hsCRP). Mixed effect model was used to investigate the significance of the relationship between temperature and cardiovascular markers. Decreased ambient temperature was associated with an increase in systolic and diastolic blood pressures, platelet count and serum low density lipoprotein-cholesterol concentration. In contrast, high density lipoprotein-cholesterol level declined with decreasing temperature. The hsCRP level increased with decreasing temperature in the minimum temperatures below 0°C, but revealed a reverse association above. Our study suggests that excess cardiovascular mortality in cold weather might be associated with temperature-related variations of cardiovascular markers.

AB - Cardiovascular mortality has been shown to increase in the winter. However, it is unclear whether cold temperature affects indicators known as cardiovascular markers. We evaluated the association between ambient temperature and cardiovascular markers using data collected retrospectively from 55,567 adults who had visited a health check-up clinic between 1995 and 2008. Non-parametric smoothing regressions were fitted to determine the shapes of association between temperature and cardiovascular markers such as blood pressure, lipid profiles, platelet count, and high sensitivity C-reactive protein (hsCRP). Mixed effect model was used to investigate the significance of the relationship between temperature and cardiovascular markers. Decreased ambient temperature was associated with an increase in systolic and diastolic blood pressures, platelet count and serum low density lipoprotein-cholesterol concentration. In contrast, high density lipoprotein-cholesterol level declined with decreasing temperature. The hsCRP level increased with decreasing temperature in the minimum temperatures below 0°C, but revealed a reverse association above. Our study suggests that excess cardiovascular mortality in cold weather might be associated with temperature-related variations of cardiovascular markers.

KW - Adult

KW - Biomarkers/blood

KW - Blood Pressure/physiology

KW - C-Reactive Protein/analysis

KW - Cardiovascular Diseases/blood

KW - Cholesterol, HDL/blood

KW - Cholesterol, LDL/blood

KW - Cold Temperature

KW - Female

KW - Humans

KW - Lipids/blood

KW - Male

KW - Middle Aged

KW - Models, Biological

KW - Platelet Count

KW - Republic of Korea/epidemiology

KW - Retrospective Studies

U2 - 10.1016/j.scitotenv.2012.02.070

DO - 10.1016/j.scitotenv.2012.02.070

M3 - Journal article

C2 - 22846766

VL - 435-436

SP - 74

EP - 79

JO - Science of the Total Environment

JF - Science of the Total Environment

SN - 0048-9697

ER -

ID: 230071720