Long-term air pollution and road traffic noise exposure and COPD

Long-term air pollution and road traffic noise exposure and COPD: the Danish Nurse Cohort

Research output: Contribution to journal › Journal article › Research › peer-review

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Long-term air pollution and road traffic noise exposure and COPD : the Danish Nurse Cohort. / Liu, Shuo; Lim, Youn-Hee; Pedersen, Marie; Jørgensen, Jeanette T; Amini, Heresh; Cole-Hunter, Thomas; Mehta, Amar J; So, Rina; Mortensen, Laust H; Westendorp, Rudi G J; Loft, Steffen; Bräuner, Elvira V; Ketzel, Matthias; Hertel, Ole; Brandt, Jørgen; Jensen, Steen S; Christensen, Jesper H.; Sigsgaard, Torben; Geels, Camilla; Frohn, Lise M; Brborić, Maja; Radonić, Jelena; Sekulic, Maja Turk; Bønnelykke, Klaus; Backalarz, Claus; Simonsen, Mette K; Andersen, Zorana J.

In: The European respiratory journal, Vol. 57, No. 6, 2021.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Liu, S, Lim, Y-H, Pedersen, M, Jørgensen, JT, Amini, H, Cole-Hunter, T, Mehta, AJ, So, R, Mortensen, LH, Westendorp, RGJ, Loft, S, Bräuner, EV, Ketzel, M, Hertel, O, Brandt, J, Jensen, SS, Christensen, JH, Sigsgaard, T, Geels, C, Frohn, LM, Brborić, M, Radonić, J, Sekulic, MT, Bønnelykke, K, Backalarz, C, Simonsen, MK & Andersen, ZJ 2021, 'Long-term air pollution and road traffic noise exposure and COPD: the Danish Nurse Cohort', The European respiratory journal, vol. 57, no. 6. https://doi.org/10.1183/13993003.04594-2020

APA

Liu, S., Lim, Y-H., Pedersen, M., Jørgensen, J. T., Amini, H., Cole-Hunter, T., Mehta, A. J., So, R., Mortensen, L. H., Westendorp, R. G. J., Loft, S., Bräuner, E. V., Ketzel, M., Hertel, O., Brandt, J., Jensen, S. S., Christensen, J. H., Sigsgaard, T., Geels, C., ... Andersen, Z. J. (2021). Long-term air pollution and road traffic noise exposure and COPD: the Danish Nurse Cohort. The European respiratory journal, 57(6). https://doi.org/10.1183/13993003.04594-2020

Vancouver

Liu S, Lim Y-H, Pedersen M, Jørgensen JT, Amini H, Cole-Hunter T et al. Long-term air pollution and road traffic noise exposure and COPD: the Danish Nurse Cohort. The European respiratory journal. 2021;57(6). https://doi.org/10.1183/13993003.04594-2020

Author

Liu, Shuo ; Lim, Youn-Hee ; Pedersen, Marie ; Jørgensen, Jeanette T ; Amini, Heresh ; Cole-Hunter, Thomas ; Mehta, Amar J ; So, Rina ; Mortensen, Laust H ; Westendorp, Rudi G J ; Loft, Steffen ; Bräuner, Elvira V ; Ketzel, Matthias ; Hertel, Ole ; Brandt, Jørgen ; Jensen, Steen S ; Christensen, Jesper H. ; Sigsgaard, Torben ; Geels, Camilla ; Frohn, Lise M ; Brborić, Maja ; Radonić, Jelena ; Sekulic, Maja Turk ; Bønnelykke, Klaus ; Backalarz, Claus ; Simonsen, Mette K ; Andersen, Zorana J. / Long-term air pollution and road traffic noise exposure and COPD : the Danish Nurse Cohort. In: The European respiratory journal. 2021 ; Vol. 57, No. 6.

Bibtex

@article{d2752533f3234da2871f5d7f31e9d0c4,

title = "Long-term air pollution and road traffic noise exposure and COPD: the Danish Nurse Cohort",

abstract = "BACKGROUND: While air pollution has been linked to the development of chronic obstructive pulmonary disease (COPD), evidence on the role of environmental noise is just emerging. We examined the associations of long-term exposure to air pollution and road traffic noise with COPD incidence.METHODS: We defined COPD incidence for 24 538 female nurses from the Danish Nurse Cohort (age>44 years) as the first hospital contact between baseline (1993 or 1999) and 2015. We estimated residential annual mean concentrations of particulate matter with diameter<2.5 µm (PM2.5) since 1990 and nitrogen dioxide (NO2) since 1970 by the Danish DEHM/UBM/AirGIS modeling system, and road traffic noise (Lden) since 1970 by the Nord2000 model. Time-varying Cox regression models were applied to assess the associations of air pollution and road traffic noise with COPD incidence.RESULTS: 977 nurses developed COPD during 18.6 years' mean follow-up. We observed associations with COPD for all three exposures with hazard ratios (HRs) and 95% confidence intervals (CIs) of 1.19 (1.01, 1.41) per 6.26 µg·m-3 for PM2.5, 1.13 (1.05, 1.20) per 8.19 µg·m-3 for NO2, and 1.15 (1.06, 1.25) per 10 dB for Lden. Associations with NO2 and Lden attenuated slightly after mutual adjustment, but were robust to adjustment for PM2.5. Associations with PM2.5 were attenuated to null after adjustment for either NO2 or Lden. No potential interaction effect was observed between air pollutants and noise.CONCLUSIONS: Long-term exposure to air pollution, especially traffic-related NO2, and road traffic noise were independently associated with COPD.",

author = "Shuo Liu and Youn-Hee Lim and Marie Pedersen and J{\o}rgensen, {Jeanette T} and Heresh Amini and Thomas Cole-Hunter and Mehta, {Amar J} and Rina So and Mortensen, {Laust H} and Westendorp, {Rudi G J} and Steffen Loft and Br{\"a}uner, {Elvira V} and Matthias Ketzel and Ole Hertel and J{\o}rgen Brandt and Jensen, {Steen S} and Christensen, {Jesper H.} and Torben Sigsgaard and Camilla Geels and Frohn, {Lise M} and Maja Brbori{\'c} and Jelena Radoni{\'c} and Sekulic, {Maja Turk} and Klaus B{\o}nnelykke and Claus Backalarz and Simonsen, {Mette K} and Andersen, {Zorana J}",

note = "Copyright {\textcopyright}The authors 2021. For reproduction rights and permissions contact permissions@ersnet.org.",

year = "2021",

doi = "10.1183/13993003.04594-2020",

language = "English",

volume = "57",

journal = "The European respiratory journal",

issn = "0903-1936",

publisher = "European Respiratory Society",

number = "6",

}

RIS

TY - JOUR

T1 - Long-term air pollution and road traffic noise exposure and COPD

T2 - the Danish Nurse Cohort

AU - Liu, Shuo

AU - Lim, Youn-Hee

AU - Pedersen, Marie

AU - Jørgensen, Jeanette T

AU - Amini, Heresh

AU - Cole-Hunter, Thomas

AU - Mehta, Amar J

AU - So, Rina

AU - Mortensen, Laust H

AU - Westendorp, Rudi G J

AU - Loft, Steffen

AU - Bräuner, Elvira V

AU - Ketzel, Matthias

AU - Hertel, Ole

AU - Brandt, Jørgen

AU - Jensen, Steen S

AU - Christensen, Jesper H.

AU - Sigsgaard, Torben

AU - Geels, Camilla

AU - Frohn, Lise M

AU - Brborić, Maja

AU - Radonić, Jelena

AU - Sekulic, Maja Turk

AU - Bønnelykke, Klaus

AU - Backalarz, Claus

AU - Simonsen, Mette K

AU - Andersen, Zorana J

PY - 2021

Y1 - 2021

N2 - BACKGROUND: While air pollution has been linked to the development of chronic obstructive pulmonary disease (COPD), evidence on the role of environmental noise is just emerging. We examined the associations of long-term exposure to air pollution and road traffic noise with COPD incidence.METHODS: We defined COPD incidence for 24 538 female nurses from the Danish Nurse Cohort (age>44 years) as the first hospital contact between baseline (1993 or 1999) and 2015. We estimated residential annual mean concentrations of particulate matter with diameter<2.5 µm (PM2.5) since 1990 and nitrogen dioxide (NO2) since 1970 by the Danish DEHM/UBM/AirGIS modeling system, and road traffic noise (Lden) since 1970 by the Nord2000 model. Time-varying Cox regression models were applied to assess the associations of air pollution and road traffic noise with COPD incidence.RESULTS: 977 nurses developed COPD during 18.6 years' mean follow-up. We observed associations with COPD for all three exposures with hazard ratios (HRs) and 95% confidence intervals (CIs) of 1.19 (1.01, 1.41) per 6.26 µg·m-3 for PM2.5, 1.13 (1.05, 1.20) per 8.19 µg·m-3 for NO2, and 1.15 (1.06, 1.25) per 10 dB for Lden. Associations with NO2 and Lden attenuated slightly after mutual adjustment, but were robust to adjustment for PM2.5. Associations with PM2.5 were attenuated to null after adjustment for either NO2 or Lden. No potential interaction effect was observed between air pollutants and noise.CONCLUSIONS: Long-term exposure to air pollution, especially traffic-related NO2, and road traffic noise were independently associated with COPD.

AB - BACKGROUND: While air pollution has been linked to the development of chronic obstructive pulmonary disease (COPD), evidence on the role of environmental noise is just emerging. We examined the associations of long-term exposure to air pollution and road traffic noise with COPD incidence.METHODS: We defined COPD incidence for 24 538 female nurses from the Danish Nurse Cohort (age>44 years) as the first hospital contact between baseline (1993 or 1999) and 2015. We estimated residential annual mean concentrations of particulate matter with diameter<2.5 µm (PM2.5) since 1990 and nitrogen dioxide (NO2) since 1970 by the Danish DEHM/UBM/AirGIS modeling system, and road traffic noise (Lden) since 1970 by the Nord2000 model. Time-varying Cox regression models were applied to assess the associations of air pollution and road traffic noise with COPD incidence.RESULTS: 977 nurses developed COPD during 18.6 years' mean follow-up. We observed associations with COPD for all three exposures with hazard ratios (HRs) and 95% confidence intervals (CIs) of 1.19 (1.01, 1.41) per 6.26 µg·m-3 for PM2.5, 1.13 (1.05, 1.20) per 8.19 µg·m-3 for NO2, and 1.15 (1.06, 1.25) per 10 dB for Lden. Associations with NO2 and Lden attenuated slightly after mutual adjustment, but were robust to adjustment for PM2.5. Associations with PM2.5 were attenuated to null after adjustment for either NO2 or Lden. No potential interaction effect was observed between air pollutants and noise.CONCLUSIONS: Long-term exposure to air pollution, especially traffic-related NO2, and road traffic noise were independently associated with COPD.

U2 - 10.1183/13993003.04594-2020

DO - 10.1183/13993003.04594-2020

M3 - Journal article

C2 - 33986028

VL - 57

JO - The European respiratory journal

JF - The European respiratory journal

SN - 0903-1936

IS - 6

ER -

ID: 270716265

Department of Public Health