Ten-year trends in urinary concentrations of triclosan and benzophenone-3 in the general U.S. population from 2003 to 2012

Research output: Contribution to journalJournal articleResearchpeer-review

Despite their popular use and emerging evidences of adverse health effects, consequent trends in population level triclosan and benzophenone-3 exposure have been poorly evaluated. Therefore, we examined temporal trends of urinary triclosan and benzophenone-3 concentration in the general U.S. population by combining five cycles of National Health and Nutritional Examination Survey (NHANES, 2003-2012) data. We calculated percent changes and the least square geometric means (LSGMs) of urinary triclosan and benzophenone-3 concentration from 10,232 participants by using multivariable regression models. As a result, LSGM concentration of urinary triclosan and benzophenone-3 did not show statistically significant changes over the study period. [Percent change (95% CI): Triclosan, -7.35% (-20.86, 8.47); Benzophenone-3, 7.08% (-27.88, 58.99)] However, we found decreasing trend of urinary triclosan concentration and increasing trend of urinary benzophenone-3 concentration since 2005-2006. Socio-demographic factors which affected urinary concentration of triclosan and benzophenone-3 persisted throughout 10 year study period. Highest income group showed higher level of urinary triclosan and benzophenone-3 concentration. Overall concentration of benzophenone-3 was higher in female than in male, and higher in non-Hispanic Whites than any other races/ethnicities.

Original languageEnglish
JournalEnvironmental Pollution
Issue numberPt B
Pages (from-to)803-810
Number of pages8
Publication statusPublished - 2016
Externally publishedYes

Bibliographical note

Copyright © 2015 Elsevier Ltd. All rights reserved.

    Research areas

  • Anti-Infective Agents, Local/urine, Benzophenones/urine, Environmental Monitoring, Female, Humans, Least-Squares Analysis, Male, Multivariate Analysis, Nutrition Surveys, Socioeconomic Factors, Triclosan/urine, United States

ID: 230069809