Jørgen Hilden

Jørgen Hilden

Associate professor emeritus, Associate Professor emeritus

Member of:


    1. 2021
    2. Published

      A screening method to spot biomarkers that may warn of serious events in a chronic disease - illustrated by cardiological CLARICOR trial data

      Winkel, P., Hilden, Jørgen, Jakobsen, J. C., Lindschou, J., Jensen, G. B., Kjøller, E., Sajadieh, Ahmad, Kastrup, J., Kolmos, H. J., Larsson, A., Arnlov, J., Bjerre, M. & Gluud, C., 2021, In: Clinical Chemistry and Laboratory Medicine. 59, 11, p. 1852-1860 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    3. Published

      Trajectories in severe persistent pain after groin hernia repair: A retrospective analysis

      Jensen, E. K., Bäckryd, E., Hilden, Jørgen & Werner, M. U., 2021, In: Scandinavian Journal of Pain. 21, 1, p. 70-80 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    4. 2020
    5. Published

      Prognosis and Reclassification by YKL-40 in Stable Coronary Artery Disease

      Schroder, J., Jakobsen, J. C., Winkel, P., Hilden, Jørgen, Jensen, G. B., Sajadieh, Ahmad, Larsson, A., Ärnlöv, J., Harutyunyan, M., Johansen, Julia Sidenius, Kjøller, E., Gluud, C. & Kastrup, J., 2020, In: Journal of the American Heart Association. 9, 5, e01463.

      Research output: Contribution to journalJournal articlepeer-review

    6. Published

      Prognostic value of 12 novel cardiological biomarkers in stable coronary artery disease: A 10-year follow-up of the placebo group of the Copenhagen CLARICOR trial

      Winkel, P., Jakobsen, J. C., Hilden, Jørgen, Jensen, G. B., Kjøller, E., Sajadieh, Ahmad, Kastrup, J., Kolmos, H. J., Iversen, Kasper, Bjerre, M., Larsson, A., Ärnlöv, J. & Gluud, C., 2020, In: BMJ Open. 10, 8, 7 p., e033720.

      Research output: Contribution to journalJournal articlepeer-review

    7. Published

      Serum osteoprotegerin as a long-term predictor for patients with stable coronary artery disease and its association with diabetes and statin treatment: A CLARICOR trial 10-year follow-up substudy

      Bjerre, M., Hilden, Jørgen, Winkel, P., Jensen, G. B., Kjøller, E., Sajadieh, Ahmad, Kastrup, J., Kolmos, H. J., Larsson, A., Arnlov, J., Jakobsen, J. C. & Gluud, C., 2020, In: Atherosclerosis. 301, p. 8-14 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    8. 2019
    9. Published

      Circulating endostatin as a risk factor for cardiovascular events in patients with stable coronary heart disease: A CLARICOR trial sub-study

      Ruge, T., Carlsson, A. C., Kjøller, E., Hilden, Jørgen, Kolmos, H. J., Sajadieh, Ahmad, Kastrup, J., Jensen, G. B., Larsson, A., Nowak, C., Jakobsen, J. C., Winkel, P., Gluud, C. & Arnlov, J., 2019, In: Atherosclerosis. 284, p. 202-208 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    10. Published

      Power estimations for non-primary outcomes in randomised clinical trials

      Jakobsen, J. C., Ovesen, C., Winkel, P., Hilden, Jørgen, Gluud, C. & Wetterslev, J., 2019, In: BMJ Open. 9, 6, 3 p., e027092.

      Research output: Contribution to journalJournal articlepeer-review

    11. 2018
    12. Published

      10-Year Associations Between Tumor Necrosis Factor Receptors 1 and 2 and Cardiovascular Events in Patients With Stable Coronary Heart Disease: A CLARICOR (Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart Disease) Trial Substudy

      Carlsson, A. C., Ruge, T., Kjøller, E., Hilden, Jørgen, Kolmos, H. J., Sajadieh, Ahmad, Kastrup, J., Jensen, G. B., Larsson, A., Nowak, C., Jakobsen, J. C., Winkel, P., Gluud, C. & Ärnlöv, J., 1 May 2018, In: Journal of the American Heart Association. 7, 9, 11 p., e008299.

      Research output: Contribution to journalJournal articlepeer-review

    13. Published

      Cathepsin B and S as markers for cardiovascular risk and all-cause mortality in patients with stable coronary heart disease during 10 years: a CLARICOR trial sub-study

      Wuopio, J., Hilden, Jørgen, Bring, C., Kastrup, J., Sajadieh, Ahmad, Jensen, G. B., Kjøller, E., Kolmos, H. J., Larsson, A., Jakobsen, J. C., Winkel, P., Gluud, C., Carlsson, A. C. & Ärnlöv, J., 2018, In: Atherosclerosis. 278, p. 97-102 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    14. Published

      Minimum clinically important differences in chronic pain vary considerable by baseline pain and methodological factors: systematic review of empirical studies

      Olsen, Mette Frahm, Bjerre, E., Hansen, M. D., Tendal, B., Hilden, Jørgen & Hróbjartsson, A., 2018, In: Journal of Clinical Epidemiology. 101, p. 87-106.e2 22 p.

      Research output: Contribution to journalReviewpeer-review

    15. Published

      Prognostic value of routinely available data in patients with stable coronary heart disease. A 10-year follow-up of patients sampled at random times during their disease course

      Winkel, P., Jakobsen, J. C., Hilden, Jørgen, Jensen, G., Kjøller, E., Sajadieh, Ahmad, Kastrup, J., Kolmos, H. J., Larsson, A., Arnlov, J. & Gluud, C., 2018, In: Open Heart. 5, 2, 10 p., e000808.

      Research output: Contribution to journalJournal articlepeer-review

    16. 2017
    17. Published

      Pain relief that matters to patients: systematic review of empirical studies assessing the minimum clinically important difference in acute pain

      Olsen, Mette Frahm, Bjerre, E., Hansen, M. D., Hilden, Jørgen, Landler, N. E., Tendal, B. & Hróbjartsson, A., 2017, In: B M C Medicine. 15, 18 p., 35.

      Research output: Contribution to journalReviewpeer-review

    18. Published

      Predictors for major cardiovascular outcomes in stable ischaemic heart disease (PREMAC): statistical analysis plan for data originating from the CLARICOR (clarithromycin for patients with stable coronary heart disease) trial

      Winkel, P., Jakobsen, J. C., Hilden, Jørgen, Lange, Theis, Jensen, G. B., Kjøller, E., Sajadieh, Ahmad, Kastrup, J., Kolmos, H. J., Larsson, A., Ärnlöv, J. & Gluud, C., 2017, In: Diagnostic and Prognostic Research. 1, 8 p., 10.

      Research output: Contribution to journalJournal articlepeer-review

    19. 2016
    20. Published

      Early-Phase Studies of Biomarkers: What Target Sensitivity and Specificity Values Might Confer Clinical Utility?

      Pepe, M. S., Janes, H., Li, C. I., Bossuyt, P. M., Feng, Z. & Hilden, Jørgen, May 2016, In: Clinical Chemistry. 62, 5, p. 737-742 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    21. Published

      The matching quality of experimental and control interventions in blinded pharmacological randomised clinical trials: a methodological systematic review

      Bello, S., Wei, M., Hilden, Jørgen & Hróbjartsson, A., 13 Feb 2016, In: BMC Medical Research Methodology. 16, p. 1-12 12 p., 18.

      Research output: Contribution to journalReviewpeer-review

    22. 2015
    23. Published

      The Net Reclassification Index (NRI): A Misleading Measure of Prediction Improvement Even with Independent Test Data Sets

      Pepe, M. S., Fan, J., Feng, Z., Gerds, Thomas Alexander & Hilden, Jørgen, Oct 2015, In: Statistics in BioSciences. 7, 2, p. 282-295 14 p.

      Research output: Contribution to journalJournal articlepeer-review

    24. Published

      Clarithromycin for stable coronary heart disease increases all-cause and cardiovascular mortality and cerebrovascular morbidity over 10years in the CLARICOR randomised, blinded clinical trial

      Winkel, P., Hilden, Jørgen, Hansen, J. F., Kastrup, J., Kolmos, H. J., Kjøller, E., Boje Jensen, G., Skoog, M., Lindschou, J., Gluud, C. & CLARICOR Trial Group, C. T. G., Mar 2015, In: International Journal of Cardiology. 182, p. 459-65 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    25. 2014
    26. Published

      Osteoprotegerin independently predicts mortality in patients with stable coronary artery disease: The CLARICOR trial

      Bjerre, M., Hilden, Jørgen, Kastrup, J., Skoog, M., Hansen, J. F., Kolmos, H. J., Jensen, G. B., Kjøller, E., Winkel, P., Flyvbjerg, A., Gluud, C. & CLARICOR Trial Group, C. T. G., Nov 2014, In: Scandinavian Journal of Clinical & Laboratory Investigation. 74, 8, p. 657-664 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    27. Published

      A note on the evaluation of novel biomarkers: do not rely on integrated discrimination improvement and net reclassification index

      Hilden, Jørgen & Gerds, Thomas Alexander, 30 Aug 2014, In: Statistics in Medicine. 33, 19, p. 3405-14 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    28. Published

      Calibration of models is not sufficient to justify NRI

      Gerds, Thomas Alexander & Hilden, Jørgen, 30 Aug 2014, In: Statistics in Medicine. 33, 19, p. 3419-20 2 p.

      Research output: Contribution to journalComment/debatepeer-review

    29. Published

      Agreement between public register and adjudication committee outcome in a cardiovascular randomized clinical trial

      Kjøller, E., Hilden, Jørgen, Winkel, P., Galatius, S., Frandsen, N. J., Jensen, G. B., Fischer Hansen, J., Kastrup, J., Jespersen, C. M., Hildebrandt, P., Kolmos, H. J., Gluud, C. & CLARICOR Trial Group, C. T. G., Aug 2014, In: American Heart Journal. 168, 2, p. 197–204.e4 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    30. Published

      Bias due to lack of patient blinding in clinical trials: A systematic review of trials randomizing patients to blind and nonblind sub-studies

      Hróbjartsson, A., Emanuelsson, F., Skou Thomsen, A. S., Hilden, Jørgen & Brorson, Stig, Aug 2014, In: International Journal of Epidemiology. 43, 4, p. 1272-1283 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    31. Published

      Observer bias in randomized clinical trials with time-to-event outcomes: systematic review of trials with both blinded and non-blinded outcome assessors

      Hróbjartsson, A., Thomsen, A. S. S., Emanuelsson, F., Tendal, B., Rasmussen, J. V., Hilden, Jørgen, Boutron, I., Ravaud, P. & Brorson, Stig, Jun 2014, In: International Journal of Epidemiology. 43, 3, p. 937-948 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    32. Published

      On NRI, IDI, and "good-looking" statistics with nothing underneath

      Hilden, Jørgen, Mar 2014, In: Epidemiology (Cambridge, Mass.). 25, 2, p. 265-7 3 p.

      Research output: Contribution to journalComment/debatepeer-review

    33. Published

      Risk stratification in stable coronary artery disease is possible at cardiac troponin levels below conventional detection and is improved by use of N-terminal pro-B-type natriuretic peptide

      Lyngbæk, S., Winkel, P., Gøtze, J. P., Kastrup, J., Gluud, C., Kolmos, H. J., Kjøller, E., Jensen, G. B., Hansen, J. F., Hildebrandt, P., Hilden, Jørgen & CLARICOR Trial Group, C. T. G., 2014, In: European Journal of Preventive Cardiology. 21, 10, p. 1275-1284 10 p.

      Research output: Contribution to journalJournal articlepeer-review

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