Antenatal bestemmelse af føtal RhD-blodtype baseret på føtalt DNA i plasma fra den RhD-negative mor - Sekundærpublikation
Research output: Contribution to journal › Journal article › Research › peer-review
We present a reliable test for prenatal prediction of fetal RhD type using maternal plasma from RhD- women. This test is needed for a future antenatal RH prophylaxis. A new real time PCR based assay targeting RHD exon 7 and a published assay for RHD exon 10 were used to determine the fetal RHD status in DNA extracted from plasma from 56 pregnant women in 15th -36 th week of gestation. Prediction of fetal RhD type was compared with the phenotype determined after birth, and showed 100% concordance. This setup will be of value in antenatal RH prophylaxis and in the management of immunised women.
| Translated title of the contribution | Antenatal determination of fetal RhD-blood type based on fetal DNA in plasma from the RhD-negative mother |
|---|---|
| Original language | Danish |
| Journal | Ugeskrift for Laeger |
| Volume | 168 |
| Issue number | 26-32 |
| Pages (from-to) | 2568-2570 |
| Number of pages | 3 |
| ISSN | 0041-5782 |
| Publication status | Published - 26 Jun 2006 |
ID: 198566554