Atovaquone/proguanil resistance in Africa: a case report
Research output: Contribution to journal › Journal article › Research › peer-review
The Atovaquone/proguanil combination has quickly been established as an effective chemoprophylaxis for travellers to areas with chloroquineresistant Plasmodium falciparum malaria. We describe the molecular cause of the first reported case of primary Atovaquone/proguanil resistance observed in our department in a Plasmodium falciparum infected traveller returning from West Africa, and link our findings to other reports of resistance.
| Original language | English |
|---|---|
| Journal | Scandinavian Journal of Infectious Diseases |
| Volume | 35 |
| Issue number | 11-12 |
| Pages (from-to) | 897-8 |
| Number of pages | 1 |
| ISSN | 0036-5548 |
| Publication status | Published - 2003 |
Bibliographical note
Keywords: Adult; Africa; Animals; Atovaquone; Bacterial Proteins; Chloroguanide; Cytochrome b Group; Denmark; Drug Resistance, Multiple; Drug Therapy, Combination; Ferritins; Humans; Malaria, Falciparum; Male; Microbial Sensitivity Tests; Mutation; Naphthoquinones; Pharmacogenetics; Plasmodium falciparum; Polymerase Chain Reaction; Risk Assessment; Travel; Treatment Failure
ID: 17656922