Bulky DNA adducts in white blood cells: a pooled analysis of 3,600 subjects
Research output: Contribution to journal › Journal article › Research › peer-review
Bulky DNA adducts are markers of exposure to genotoxic aromatic compounds, which reflect the ability of an individual to metabolically activate carcinogens and to repair DNA damage. Polycyclic aromatic hydrocarbons (PAHs) represent a major class of carcinogens that are capable of forming such adducts. Factors that have been reported to be related to DNA adduct levels include smoking, diet, body mass index (BMI), genetic polymorphisms, the season of collection of biologic material, and air pollutants.
|Journal||Cancer Epidemiology, Biomarkers & Prevention|
|Number of pages||8|
|Publication status||Published - 1 Dec 2010|
- DNA Adducts, Female, Humans, Leukocytes, Male, Seasons