Bulky DNA adducts in white blood cells: a pooled analysis of 3,600 subjects

Research output: Contribution to journalJournal articleResearchpeer-review

  • Fulvio Ricceri
  • Roger W Godschalk
  • Marco Peluso
  • David H Phillips
  • Antonio Agudo
  • Panagiotis Georgiadis
  • Loft, Steffen
  • Anne Tjønneland
  • Ole Raaschou-Nielsen
  • Domenico Palli
  • Frederica Perera
  • Roel Vermeulen
  • Emanuela Taioli
  • Radim J Sram
  • Armelle Munnia
  • Fabio Rosa
  • Alessandra Allione
  • Giuseppe Matullo
  • Paolo Vineis
Bulky DNA adducts are markers of exposure to genotoxic aromatic compounds, which reflect the ability of an individual to metabolically activate carcinogens and to repair DNA damage. Polycyclic aromatic hydrocarbons (PAHs) represent a major class of carcinogens that are capable of forming such adducts. Factors that have been reported to be related to DNA adduct levels include smoking, diet, body mass index (BMI), genetic polymorphisms, the season of collection of biologic material, and air pollutants.
Original languageEnglish
JournalCancer Epidemiology, Biomarkers & Prevention
Issue number12
Pages (from-to)3174-81
Number of pages8
Publication statusPublished - 1 Dec 2010

    Research areas

  • DNA Adducts, Female, Humans, Leukocytes, Male, Seasons

ID: 33595155