Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells

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The majority of testicular germ cell cancers develop through a pre-invasive carcinoma in situ (CIS) stage. The CIS cell is a neoplastic counterpart of foetal germ cells. During their development, foetal germ cells undergo extensive and essential epigenetic modifications, but little is known about epigenetic patterns in CIS cells.
Original languageEnglish
JournalBritish Journal of Cancer
Issue number8
Pages (from-to)1269-76
Number of pages8
Publication statusPublished - 12 Oct 2010

ID: 34118424