Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells
Research output: Contribution to journal › Journal article › Research › peer-review
K Almstrup, J E Nielsen, O Mlynarska, M T Jansen, A Jørgensen, N E Skakkebæk, E Rajpert-De Meyts
The majority of testicular germ cell cancers develop through a pre-invasive carcinoma in situ (CIS) stage. The CIS cell is a neoplastic counterpart of foetal germ cells. During their development, foetal germ cells undergo extensive and essential epigenetic modifications, but little is known about epigenetic patterns in CIS cells.
|Journal||British Journal of Cancer|
|Number of pages||8|
|Publication status||Published - 12 Oct 2010|