Continuation of growth hormone therapy versus placebo in transition-phase patients with growth hormone deficiency: impact on body composition, insulin sensitivity, and thyroid function
Research output: Contribution to journal › Journal article › Research
In a placebo-controlled, parallel study of 18 patients with a mean age of 20 years who had confirmed growth hormone (GH) deficiency, we evaluated body composition, insulin sensitivity, and glucose turnover at baseline (when all were receiving GH replacement); after 12 months of continued GH therapy or placebo; and after a 12-month open phase of GH therapy. In the placebo group, insulin sensitivity and fat mass increased and lipid oxidation decreased, whereas glucose oxidation increased (p
Original language | English |
---|---|
Journal | Journal of Pediatric Endocrinology and Metabolism |
Volume | 15 Suppl 5 |
Pages (from-to) | 1355-60 |
Number of pages | 6 |
ISSN | 0334-018X |
Publication status | Published - 2002 |
ID: 48484118