Copy number variation in glutathione S-transferases M1 and T1 and ischemic vascular disease: four studies and meta-analyses

Research output: Contribution to journalJournal articlepeer-review

Glutathione S-transferases (GSTs) M1 and T1 detoxify products of oxidative stress and may protect against atherosclerosis and ischemic vascular disease (IVD). We tested the hypothesis that copy number variation (CNV) in GSTM1 and GSTT1 genes, known to be associated with stepwise decreases in catalytic activity, predict risk of IVD.
Original languageEnglish
JournalCirculation: Cardiovascular Genetics
Volume4
Issue number4
Pages (from-to)418-28
Number of pages11
ISSN1942-325X
DOIs
Publication statusPublished - 2011

ID: 35372605