Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression: a randomized trial

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression : a randomized trial. / Knorr, Ulla; Vinberg, Maj; Mortensen, Erik Lykke; Winkel, Per; Gluud, Christian; Wetterslev, Jørn; Gether, Ulrik; Kessing, Lars Vedel.

In: P L o S One, Vol. 7, No. 2, 29.02.2012, p. e31980.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Knorr, U, Vinberg, M, Mortensen, EL, Winkel, P, Gluud, C, Wetterslev, J, Gether, U & Kessing, LV 2012, 'Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression: a randomized trial', P L o S One, vol. 7, no. 2, pp. e31980. https://doi.org/10.1371/journal.pone.0031980

APA

Knorr, U., Vinberg, M., Mortensen, E. L., Winkel, P., Gluud, C., Wetterslev, J., Gether, U., & Kessing, L. V. (2012). Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression: a randomized trial. P L o S One, 7(2), e31980. https://doi.org/10.1371/journal.pone.0031980

Vancouver

Knorr U, Vinberg M, Mortensen EL, Winkel P, Gluud C, Wetterslev J et al. Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression: a randomized trial. P L o S One. 2012 Feb 29;7(2):e31980. https://doi.org/10.1371/journal.pone.0031980

Author

Knorr, Ulla ; Vinberg, Maj ; Mortensen, Erik Lykke ; Winkel, Per ; Gluud, Christian ; Wetterslev, Jørn ; Gether, Ulrik ; Kessing, Lars Vedel. / Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression : a randomized trial. In: P L o S One. 2012 ; Vol. 7, No. 2. pp. e31980.

Bibtex

@article{1c4e2987dc0240daa0012a5088795eaf,
title = "Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression: a randomized trial",
abstract = "The serotonergic neurotransmitter system is closely linked to depression and personality traits. It is not known if selective serotonin reuptake inhibitors (SSRI) have an effect on neuroticism that is independent of their effect on depression. Healthy individuals with a genetic liability for depression represent a group of particular interest when investigating if intervention with SSRIs affects personality. The present trial is the first to test the hypothesis that escitalopram may reduce neuroticism in healthy first-degree relatives of patients with major depressive disorder (MD).",
author = "Ulla Knorr and Maj Vinberg and Mortensen, {Erik Lykke} and Per Winkel and Christian Gluud and J{\o}rn Wetterslev and Ulrik Gether and Kessing, {Lars Vedel}",
year = "2012",
month = feb,
day = "29",
doi = "10.1371/journal.pone.0031980",
language = "English",
volume = "7",
pages = "e31980",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "2",

}

RIS

TY - JOUR

T1 - Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression

T2 - a randomized trial

AU - Knorr, Ulla

AU - Vinberg, Maj

AU - Mortensen, Erik Lykke

AU - Winkel, Per

AU - Gluud, Christian

AU - Wetterslev, Jørn

AU - Gether, Ulrik

AU - Kessing, Lars Vedel

PY - 2012/2/29

Y1 - 2012/2/29

N2 - The serotonergic neurotransmitter system is closely linked to depression and personality traits. It is not known if selective serotonin reuptake inhibitors (SSRI) have an effect on neuroticism that is independent of their effect on depression. Healthy individuals with a genetic liability for depression represent a group of particular interest when investigating if intervention with SSRIs affects personality. The present trial is the first to test the hypothesis that escitalopram may reduce neuroticism in healthy first-degree relatives of patients with major depressive disorder (MD).

AB - The serotonergic neurotransmitter system is closely linked to depression and personality traits. It is not known if selective serotonin reuptake inhibitors (SSRI) have an effect on neuroticism that is independent of their effect on depression. Healthy individuals with a genetic liability for depression represent a group of particular interest when investigating if intervention with SSRIs affects personality. The present trial is the first to test the hypothesis that escitalopram may reduce neuroticism in healthy first-degree relatives of patients with major depressive disorder (MD).

U2 - 10.1371/journal.pone.0031980

DO - 10.1371/journal.pone.0031980

M3 - Journal article

C2 - 22393376

VL - 7

SP - e31980

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 2

ER -

ID: 38186391