Evaluating clinically significant changes in health-related quality of life: A sample of relatives of patients with severe traumatic brain injury

Research output: Contribution to journalJournal articleResearchpeer-review

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Evaluating clinically significant changes in health-related quality of life : A sample of relatives of patients with severe traumatic brain injury. / Norup, Anne; Kristensen, Karin Spangsberg; Poulsen, Ingrid; Mortensen, Erik Lykke.

In: Neuropsychological Rehabilitation, Vol. 27, No. 2, 03.2017, p. 196-215.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Norup, A, Kristensen, KS, Poulsen, I & Mortensen, EL 2017, 'Evaluating clinically significant changes in health-related quality of life: A sample of relatives of patients with severe traumatic brain injury', Neuropsychological Rehabilitation, vol. 27, no. 2, pp. 196-215. https://doi.org/10.1080/09602011.2015.1076484

APA

Norup, A., Kristensen, K. S., Poulsen, I., & Mortensen, E. L. (2017). Evaluating clinically significant changes in health-related quality of life: A sample of relatives of patients with severe traumatic brain injury. Neuropsychological Rehabilitation, 27(2), 196-215. https://doi.org/10.1080/09602011.2015.1076484

Vancouver

Norup A, Kristensen KS, Poulsen I, Mortensen EL. Evaluating clinically significant changes in health-related quality of life: A sample of relatives of patients with severe traumatic brain injury. Neuropsychological Rehabilitation. 2017 Mar;27(2):196-215. https://doi.org/10.1080/09602011.2015.1076484

Author

Norup, Anne ; Kristensen, Karin Spangsberg ; Poulsen, Ingrid ; Mortensen, Erik Lykke. / Evaluating clinically significant changes in health-related quality of life : A sample of relatives of patients with severe traumatic brain injury. In: Neuropsychological Rehabilitation. 2017 ; Vol. 27, No. 2. pp. 196-215.

Bibtex

@article{a653a89c7a4b426babd11e546b595a83,
title = "Evaluating clinically significant changes in health-related quality of life: A sample of relatives of patients with severe traumatic brain injury",
abstract = "The objective of the study was to investigate change and predictors of change in health-related quality of life (HRQoL) in relatives of patients with severe traumatic brain injury (TBI) during rehabilitation, and to analyse associations between changes in HRQoL and symptoms of anxiety and depression. The Vitality (VT), Mental Health (MH), Social Function (SF) and the Role Emotional (RE) scales from the Short Form 36, and the anxiety and depression scales from the Symptom Checklist-90 – Revised were used. Of the 62 relatives, 24.6{\%} experienced a reliable improvement on the VT scale, 53.2{\%} on the MH scale, 27.4{\%} on the SF scale and 16.1{\%} on the RE scale. Of the relatives, 24.0{\%} experienced clinically significant change (CSC) on the VT scale, 19.6{\%} on the MH scale, 21.6{\%} on the SF scale, and 19.2{\%} on the RE scale. Relatives’ age and higher patient Glasgow Coma Scale score predicted the experience of CSC in RE, and change on the Functional Independence Measure in patients predicted CSC on the MH scale. Improvements in VT as well as MH were associated with improvement in symptoms of anxiety and depression, and improvement in SF was associated with improvement in symptoms of depression. About one-fifth of the sample experienced a CSC on one of the four HRQoL measures. Relatives experiencing CSC tended to be related to patients who showed more improvement during rehabilitation. Improvements in HRQoL were associated with improvements in symptoms of anxiety and depression.",
keywords = "TBI, HRQoL, Sub-acute rehabilitation, TBI-caregivers, Reliable change index, Clinically significant change",
author = "Anne Norup and Kristensen, {Karin Spangsberg} and Ingrid Poulsen and Mortensen, {Erik Lykke}",
year = "2017",
month = "3",
doi = "10.1080/09602011.2015.1076484",
language = "English",
volume = "27",
pages = "196--215",
journal = "Neuropsychological Rehabilitation",
issn = "0960-2011",
publisher = "Routledge",
number = "2",

}

RIS

TY - JOUR

T1 - Evaluating clinically significant changes in health-related quality of life

T2 - A sample of relatives of patients with severe traumatic brain injury

AU - Norup, Anne

AU - Kristensen, Karin Spangsberg

AU - Poulsen, Ingrid

AU - Mortensen, Erik Lykke

PY - 2017/3

Y1 - 2017/3

N2 - The objective of the study was to investigate change and predictors of change in health-related quality of life (HRQoL) in relatives of patients with severe traumatic brain injury (TBI) during rehabilitation, and to analyse associations between changes in HRQoL and symptoms of anxiety and depression. The Vitality (VT), Mental Health (MH), Social Function (SF) and the Role Emotional (RE) scales from the Short Form 36, and the anxiety and depression scales from the Symptom Checklist-90 – Revised were used. Of the 62 relatives, 24.6% experienced a reliable improvement on the VT scale, 53.2% on the MH scale, 27.4% on the SF scale and 16.1% on the RE scale. Of the relatives, 24.0% experienced clinically significant change (CSC) on the VT scale, 19.6% on the MH scale, 21.6% on the SF scale, and 19.2% on the RE scale. Relatives’ age and higher patient Glasgow Coma Scale score predicted the experience of CSC in RE, and change on the Functional Independence Measure in patients predicted CSC on the MH scale. Improvements in VT as well as MH were associated with improvement in symptoms of anxiety and depression, and improvement in SF was associated with improvement in symptoms of depression. About one-fifth of the sample experienced a CSC on one of the four HRQoL measures. Relatives experiencing CSC tended to be related to patients who showed more improvement during rehabilitation. Improvements in HRQoL were associated with improvements in symptoms of anxiety and depression.

AB - The objective of the study was to investigate change and predictors of change in health-related quality of life (HRQoL) in relatives of patients with severe traumatic brain injury (TBI) during rehabilitation, and to analyse associations between changes in HRQoL and symptoms of anxiety and depression. The Vitality (VT), Mental Health (MH), Social Function (SF) and the Role Emotional (RE) scales from the Short Form 36, and the anxiety and depression scales from the Symptom Checklist-90 – Revised were used. Of the 62 relatives, 24.6% experienced a reliable improvement on the VT scale, 53.2% on the MH scale, 27.4% on the SF scale and 16.1% on the RE scale. Of the relatives, 24.0% experienced clinically significant change (CSC) on the VT scale, 19.6% on the MH scale, 21.6% on the SF scale, and 19.2% on the RE scale. Relatives’ age and higher patient Glasgow Coma Scale score predicted the experience of CSC in RE, and change on the Functional Independence Measure in patients predicted CSC on the MH scale. Improvements in VT as well as MH were associated with improvement in symptoms of anxiety and depression, and improvement in SF was associated with improvement in symptoms of depression. About one-fifth of the sample experienced a CSC on one of the four HRQoL measures. Relatives experiencing CSC tended to be related to patients who showed more improvement during rehabilitation. Improvements in HRQoL were associated with improvements in symptoms of anxiety and depression.

KW - TBI

KW - HRQoL

KW - Sub-acute rehabilitation

KW - TBI-caregivers

KW - Reliable change index

KW - Clinically significant change

U2 - 10.1080/09602011.2015.1076484

DO - 10.1080/09602011.2015.1076484

M3 - Journal article

VL - 27

SP - 196

EP - 215

JO - Neuropsychological Rehabilitation

JF - Neuropsychological Rehabilitation

SN - 0960-2011

IS - 2

ER -

ID: 174267925