Evaluation of simple tests for detection of HIV antibodies: analysis of interobserver variation in Tanzania

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Evaluation of simple tests for detection of HIV antibodies: analysis of interobserver variation in Tanzania. / Jørgensen, A; Shao, Jing; Maselle, S; Yangi, E; Thomsen, A; Matunda, S; Bygbjerg, Ib Christian; Gøtzsche, P; Svendsen, J; Skinhøj.

In: Scandinavian Journal of Infectious Diseases, Vol. 22, No. 3, 01.01.1990, p. 283-5.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Jørgensen, A, Shao, J, Maselle, S, Yangi, E, Thomsen, A, Matunda, S, Bygbjerg, IC, Gøtzsche, P, Svendsen, J & Skinhøj 1990, 'Evaluation of simple tests for detection of HIV antibodies: analysis of interobserver variation in Tanzania', Scandinavian Journal of Infectious Diseases, vol. 22, no. 3, pp. 283-5.

APA

Jørgensen, A., Shao, J., Maselle, S., Yangi, E., Thomsen, A., Matunda, S., Bygbjerg, I. C., Gøtzsche, P., Svendsen, J., & Skinhøj (1990). Evaluation of simple tests for detection of HIV antibodies: analysis of interobserver variation in Tanzania. Scandinavian Journal of Infectious Diseases, 22(3), 283-5.

Vancouver

Jørgensen A, Shao J, Maselle S, Yangi E, Thomsen A, Matunda S et al. Evaluation of simple tests for detection of HIV antibodies: analysis of interobserver variation in Tanzania. Scandinavian Journal of Infectious Diseases. 1990 Jan 1;22(3):283-5.

Author

Jørgensen, A ; Shao, Jing ; Maselle, S ; Yangi, E ; Thomsen, A ; Matunda, S ; Bygbjerg, Ib Christian ; Gøtzsche, P ; Svendsen, J ; Skinhøj. / Evaluation of simple tests for detection of HIV antibodies: analysis of interobserver variation in Tanzania. In: Scandinavian Journal of Infectious Diseases. 1990 ; Vol. 22, No. 3. pp. 283-5.

Bibtex

@article{e0da92fd2b73488c94d12e74dd94bc04,
title = "Evaluation of simple tests for detection of HIV antibodies: analysis of interobserver variation in Tanzania",
abstract = "200 sera were tested for HIV antibodies with different tests in Tanzania. The results were interpreted by 5 different observers with different laboratory experience. There was considerable variation between observers and between testing methods. HIV-Chek was easiest to perform with little interobserver variation, but a few probably false negative readings were seen. Serodia gave many false positives. Western Blots gave more diverging results due to indeterminate sera and lack of training. HIV-Chek seems best when time, facilities, and training are limited and if combined with Serodia false negative results can be excluded.",
keywords = "Blotting, Western, Enzyme-Linked Immunosorbent Assay, False Negative Reactions, False Positive Reactions, HIV Antibodies, HIV Infections, Humans, Observer Variation, Predictive Value of Tests, Tanzania",
author = "A J{\o}rgensen and Jing Shao and S Maselle and E Yangi and A Thomsen and S Matunda and Bygbjerg, {Ib Christian} and P G{\o}tzsche and J Svendsen and Skinh{\o}j",
year = "1990",
month = jan,
day = "1",
language = "English",
volume = "22",
pages = "283--5",
journal = "Infectious Diseases",
issn = "2374-4235",
publisher = "Taylor & Francis",
number = "3",

}

RIS

TY - JOUR

T1 - Evaluation of simple tests for detection of HIV antibodies: analysis of interobserver variation in Tanzania

AU - Jørgensen, A

AU - Shao, Jing

AU - Maselle, S

AU - Yangi, E

AU - Thomsen, A

AU - Matunda, S

AU - Bygbjerg, Ib Christian

AU - Gøtzsche, P

AU - Svendsen, J

AU - Skinhøj, null

PY - 1990/1/1

Y1 - 1990/1/1

N2 - 200 sera were tested for HIV antibodies with different tests in Tanzania. The results were interpreted by 5 different observers with different laboratory experience. There was considerable variation between observers and between testing methods. HIV-Chek was easiest to perform with little interobserver variation, but a few probably false negative readings were seen. Serodia gave many false positives. Western Blots gave more diverging results due to indeterminate sera and lack of training. HIV-Chek seems best when time, facilities, and training are limited and if combined with Serodia false negative results can be excluded.

AB - 200 sera were tested for HIV antibodies with different tests in Tanzania. The results were interpreted by 5 different observers with different laboratory experience. There was considerable variation between observers and between testing methods. HIV-Chek was easiest to perform with little interobserver variation, but a few probably false negative readings were seen. Serodia gave many false positives. Western Blots gave more diverging results due to indeterminate sera and lack of training. HIV-Chek seems best when time, facilities, and training are limited and if combined with Serodia false negative results can be excluded.

KW - Blotting, Western

KW - Enzyme-Linked Immunosorbent Assay

KW - False Negative Reactions

KW - False Positive Reactions

KW - HIV Antibodies

KW - HIV Infections

KW - Humans

KW - Observer Variation

KW - Predictive Value of Tests

KW - Tanzania

M3 - Journal article

C2 - 2371543

VL - 22

SP - 283

EP - 285

JO - Infectious Diseases

JF - Infectious Diseases

SN - 2374-4235

IS - 3

ER -

ID: 33890974