Higher mortality in women living in high-participation areas of a population-based health check and lifestyle intervention study
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Higher mortality in women living in high-participation areas of a population-based health check and lifestyle intervention study. / Bender, Anne Mette; Jorgensen, Torben; Pisinger, Charlotta.
In: International Journal of Public Health, Vol. 64, No. 1, 2019, p. 107-114.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Higher mortality in women living in high-participation areas of a population-based health check and lifestyle intervention study
AU - Bender, Anne Mette
AU - Jorgensen, Torben
AU - Pisinger, Charlotta
PY - 2019
Y1 - 2019
N2 - ObjectivesThe aim was to study whether the effects of a population-based health check and lifestyle intervention differed according to study participation rate.MethodsAll persons living in 73 areas of Copenhagen County, Denmark, were included in the Inter99 randomized trial in 1999 (intervention group n = 11,483; control group n = 47,122). All persons in the intervention group were invited for health checks and were offered lifestyle counseling if they were at high risk of ischemic heart disease. Areas were divided into low 35–49%, middle 50–54% and high ≥ 55% health check participation. All persons were followed in registers for 10-year cause-specific mortality.ResultsIn high-participation areas, there was a significantly higher risk of lifestyle-(HR 1.37 [1.04, 1.79]) and cancer-related deaths (HR 1.47 [1.08, 2.02]) among women in the intervention group than control group. Regarding smoking-related cancer deaths, differences were even more pronounced. Among men, no significant difference in mortality was seen between control and intervention groups.ConclusionsThe results of this paper suggest that among women, the health check and lifestyle intervention may increase the risk of lifestyle and cancer-related deaths.
AB - ObjectivesThe aim was to study whether the effects of a population-based health check and lifestyle intervention differed according to study participation rate.MethodsAll persons living in 73 areas of Copenhagen County, Denmark, were included in the Inter99 randomized trial in 1999 (intervention group n = 11,483; control group n = 47,122). All persons in the intervention group were invited for health checks and were offered lifestyle counseling if they were at high risk of ischemic heart disease. Areas were divided into low 35–49%, middle 50–54% and high ≥ 55% health check participation. All persons were followed in registers for 10-year cause-specific mortality.ResultsIn high-participation areas, there was a significantly higher risk of lifestyle-(HR 1.37 [1.04, 1.79]) and cancer-related deaths (HR 1.47 [1.08, 2.02]) among women in the intervention group than control group. Regarding smoking-related cancer deaths, differences were even more pronounced. Among men, no significant difference in mortality was seen between control and intervention groups.ConclusionsThe results of this paper suggest that among women, the health check and lifestyle intervention may increase the risk of lifestyle and cancer-related deaths.
KW - Cancer
KW - Health check
KW - Lifestyle intervention
KW - Mortality
KW - Participation rate
KW - Randomized controlled trial
U2 - 10.1007/s00038-018-1179-2
DO - 10.1007/s00038-018-1179-2
M3 - Journal article
C2 - 30539193
VL - 64
SP - 107
EP - 114
JO - International Journal of Public Health (Print Edition)
JF - International Journal of Public Health (Print Edition)
SN - 1661-8556
IS - 1
ER -
ID: 213540958