Intelligence Test Scores Before and After Alcohol-Related Disorders—A Longitudinal Study of Danish Male Conscripts

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Intelligence Test Scores Before and After Alcohol-Related Disorders—A Longitudinal Study of Danish Male Conscripts. / Grønkjær, Marie; Flensborg-Madsen, Trine; Osler, Merete; Sørensen, Holger Jelling; Becker, Ulrik; Mortensen, Erik Lykke.

In: Alcoholism: Clinical and Experimental Research, Vol. 43, No. 10, 01.01.2019, p. 2187-2195.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Grønkjær, M, Flensborg-Madsen, T, Osler, M, Sørensen, HJ, Becker, U & Mortensen, EL 2019, 'Intelligence Test Scores Before and After Alcohol-Related Disorders—A Longitudinal Study of Danish Male Conscripts', Alcoholism: Clinical and Experimental Research, vol. 43, no. 10, pp. 2187-2195. https://doi.org/10.1111/acer.14174

APA

Grønkjær, M., Flensborg-Madsen, T., Osler, M., Sørensen, H. J., Becker, U., & Mortensen, E. L. (2019). Intelligence Test Scores Before and After Alcohol-Related Disorders—A Longitudinal Study of Danish Male Conscripts. Alcoholism: Clinical and Experimental Research, 43(10), 2187-2195. https://doi.org/10.1111/acer.14174

Vancouver

Grønkjær M, Flensborg-Madsen T, Osler M, Sørensen HJ, Becker U, Mortensen EL. Intelligence Test Scores Before and After Alcohol-Related Disorders—A Longitudinal Study of Danish Male Conscripts. Alcoholism: Clinical and Experimental Research. 2019 Jan 1;43(10):2187-2195. https://doi.org/10.1111/acer.14174

Author

Grønkjær, Marie ; Flensborg-Madsen, Trine ; Osler, Merete ; Sørensen, Holger Jelling ; Becker, Ulrik ; Mortensen, Erik Lykke. / Intelligence Test Scores Before and After Alcohol-Related Disorders—A Longitudinal Study of Danish Male Conscripts. In: Alcoholism: Clinical and Experimental Research. 2019 ; Vol. 43, No. 10. pp. 2187-2195.

Bibtex

@article{e0eeb58abec64520b709ab606f456f5a,
title = "Intelligence Test Scores Before and After Alcohol-Related Disorders—A Longitudinal Study of Danish Male Conscripts",
abstract = "Background: Existing studies on intellectual consequences of alcohol-related disorders are primarily cross-sectional and compare intelligence test scores of individuals with and without alcohol-related disorders, hence mixing the influence of alcohol-related disorders and predisposing factors such as premorbid intelligence. In this large-scale study, the primary aim was to estimate associations of alcohol-related disorders with changes in intelligence test scores from early adulthood to late midlife. Methods: Data were drawn from a follow-up study on middle-aged men, which included a re-examination of the same intelligence test as completed in young adulthood at military conscription (total analytic sample = 2,499). Alcohol-related hospital diagnoses were obtained from national health registries, whereas treatment for alcohol problems was self-reported at follow-up. The analyses included adjustment for year of birth, retest interval, baseline intelligence quotient (IQ) score, education, smoking, alcohol consumption, and psychiatric and somatic comorbidity. Results: Individuals with alcohol-related hospital diagnoses (8{\%}) had a significantly lower baseline IQ score (95.0 vs. 100.5, p < 0.001) and a larger decline in IQ scores from baseline to follow-up (−8.5 vs. −4.8, p < 0.001) than individuals without such diagnoses. The larger decline in IQ scores with alcohol-related hospital diagnoses remained statistically significant after adjustment for all the covariates. Similar results were revealed when IQ scores before and after self-reported treatment for alcohol problems (10{\%}) were examined. Conclusions: Individuals with alcohol-related disorders have a lower intelligence test score both in young adulthood and in late midlife, and these disorders, moreover, seem to be associated with more age-related decline in intelligence test scores. Thus, low mean intellectual ability observed in individuals with alcohol-related disorders is probably a result of both lower premorbid intelligence and more intellectual decline.",
keywords = "Alcohol-Related Disorders, Intellectual Changes, Intelligence, Intelligence Quotient, Longitudinal Study",
author = "Marie Gr{\o}nkj{\ae}r and Trine Flensborg-Madsen and Merete Osler and S{\o}rensen, {Holger Jelling} and Ulrik Becker and Mortensen, {Erik Lykke}",
year = "2019",
month = "1",
day = "1",
doi = "10.1111/acer.14174",
language = "English",
volume = "43",
pages = "2187--2195",
journal = "Alcoholism: Clinical and Experimental Research",
issn = "0145-6008",
publisher = "Wiley-Blackwell",
number = "10",

}

RIS

TY - JOUR

T1 - Intelligence Test Scores Before and After Alcohol-Related Disorders—A Longitudinal Study of Danish Male Conscripts

AU - Grønkjær, Marie

AU - Flensborg-Madsen, Trine

AU - Osler, Merete

AU - Sørensen, Holger Jelling

AU - Becker, Ulrik

AU - Mortensen, Erik Lykke

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Background: Existing studies on intellectual consequences of alcohol-related disorders are primarily cross-sectional and compare intelligence test scores of individuals with and without alcohol-related disorders, hence mixing the influence of alcohol-related disorders and predisposing factors such as premorbid intelligence. In this large-scale study, the primary aim was to estimate associations of alcohol-related disorders with changes in intelligence test scores from early adulthood to late midlife. Methods: Data were drawn from a follow-up study on middle-aged men, which included a re-examination of the same intelligence test as completed in young adulthood at military conscription (total analytic sample = 2,499). Alcohol-related hospital diagnoses were obtained from national health registries, whereas treatment for alcohol problems was self-reported at follow-up. The analyses included adjustment for year of birth, retest interval, baseline intelligence quotient (IQ) score, education, smoking, alcohol consumption, and psychiatric and somatic comorbidity. Results: Individuals with alcohol-related hospital diagnoses (8%) had a significantly lower baseline IQ score (95.0 vs. 100.5, p < 0.001) and a larger decline in IQ scores from baseline to follow-up (−8.5 vs. −4.8, p < 0.001) than individuals without such diagnoses. The larger decline in IQ scores with alcohol-related hospital diagnoses remained statistically significant after adjustment for all the covariates. Similar results were revealed when IQ scores before and after self-reported treatment for alcohol problems (10%) were examined. Conclusions: Individuals with alcohol-related disorders have a lower intelligence test score both in young adulthood and in late midlife, and these disorders, moreover, seem to be associated with more age-related decline in intelligence test scores. Thus, low mean intellectual ability observed in individuals with alcohol-related disorders is probably a result of both lower premorbid intelligence and more intellectual decline.

AB - Background: Existing studies on intellectual consequences of alcohol-related disorders are primarily cross-sectional and compare intelligence test scores of individuals with and without alcohol-related disorders, hence mixing the influence of alcohol-related disorders and predisposing factors such as premorbid intelligence. In this large-scale study, the primary aim was to estimate associations of alcohol-related disorders with changes in intelligence test scores from early adulthood to late midlife. Methods: Data were drawn from a follow-up study on middle-aged men, which included a re-examination of the same intelligence test as completed in young adulthood at military conscription (total analytic sample = 2,499). Alcohol-related hospital diagnoses were obtained from national health registries, whereas treatment for alcohol problems was self-reported at follow-up. The analyses included adjustment for year of birth, retest interval, baseline intelligence quotient (IQ) score, education, smoking, alcohol consumption, and psychiatric and somatic comorbidity. Results: Individuals with alcohol-related hospital diagnoses (8%) had a significantly lower baseline IQ score (95.0 vs. 100.5, p < 0.001) and a larger decline in IQ scores from baseline to follow-up (−8.5 vs. −4.8, p < 0.001) than individuals without such diagnoses. The larger decline in IQ scores with alcohol-related hospital diagnoses remained statistically significant after adjustment for all the covariates. Similar results were revealed when IQ scores before and after self-reported treatment for alcohol problems (10%) were examined. Conclusions: Individuals with alcohol-related disorders have a lower intelligence test score both in young adulthood and in late midlife, and these disorders, moreover, seem to be associated with more age-related decline in intelligence test scores. Thus, low mean intellectual ability observed in individuals with alcohol-related disorders is probably a result of both lower premorbid intelligence and more intellectual decline.

KW - Alcohol-Related Disorders

KW - Intellectual Changes

KW - Intelligence

KW - Intelligence Quotient

KW - Longitudinal Study

U2 - 10.1111/acer.14174

DO - 10.1111/acer.14174

M3 - Journal article

C2 - 31386205

AN - SCOPUS:85070962353

VL - 43

SP - 2187

EP - 2195

JO - Alcoholism: Clinical and Experimental Research

JF - Alcoholism: Clinical and Experimental Research

SN - 0145-6008

IS - 10

ER -

ID: 227104871