Movements of the wrist and the risk of carpal tunnel syndrome: a nationwide cohort study using objective exposure measurements
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Movements of the wrist and the risk of carpal tunnel syndrome : a nationwide cohort study using objective exposure measurements. / Lund, Christina Bach; Mikkelsen, Sigurd; Thygesen, Lau Caspar; Hansson, Gert Åke; Thomsen, Jane Frølund.
In: Occupational and Environmental Medicine, Vol. 76, No. 8, 2019, p. 519-526.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Movements of the wrist and the risk of carpal tunnel syndrome
T2 - a nationwide cohort study using objective exposure measurements
AU - Lund, Christina Bach
AU - Mikkelsen, Sigurd
AU - Thygesen, Lau Caspar
AU - Hansson, Gert Åke
AU - Thomsen, Jane Frølund
PY - 2019
Y1 - 2019
N2 - Objectives We conducted a large cohort study to investigate the association between work-related wrist movements and carpal tunnel syndrome (CTS). Methods Electro-goniometric measurements of wrist movements were performed for 30 jobs (eg, office work, child care, laundry work and slaughterhouse work). We measured wrist angular velocity, mean power frequency (MPF) and range of motion (ROM). We established a cohort of Danish citizens born 1940-1979 who held one of these jobs from age 18-80 years, using Danish national registers with annual employment information from 1992 to 2014. We updated the cohort by calendar year with job-specific and sex-specific means of measured exposures. Dates of a first diagnosis or operation because of CTS were retrieved from the Danish National Patient Register. The risk of CTS by quintiles of preceding exposure levels was assessed by adjusted incidence rate ratios (IRR adj) using Poisson regression models. Results We found a clear exposure-response association between wrist angular velocity and CTS with an IRR adj of 2.31 (95% CI 2.09 to 2.56) when exposed to the highest level compared with the lowest. MPF also showed an exposure-response pattern, although less clear, with an IRR adj of 1.83 (1.68 to 1.98) for the highest compared with the lowest exposure level. ROM showed no clear pattern. Exposure-response patterns were different for men and women. Conclusions High levels of wrist movement were associated with an increased risk of CTS. Preventive strategies should be aimed at jobs with high levels of wrist movements such as cleaning, laundry work and slaughterhouse work.
AB - Objectives We conducted a large cohort study to investigate the association between work-related wrist movements and carpal tunnel syndrome (CTS). Methods Electro-goniometric measurements of wrist movements were performed for 30 jobs (eg, office work, child care, laundry work and slaughterhouse work). We measured wrist angular velocity, mean power frequency (MPF) and range of motion (ROM). We established a cohort of Danish citizens born 1940-1979 who held one of these jobs from age 18-80 years, using Danish national registers with annual employment information from 1992 to 2014. We updated the cohort by calendar year with job-specific and sex-specific means of measured exposures. Dates of a first diagnosis or operation because of CTS were retrieved from the Danish National Patient Register. The risk of CTS by quintiles of preceding exposure levels was assessed by adjusted incidence rate ratios (IRR adj) using Poisson regression models. Results We found a clear exposure-response association between wrist angular velocity and CTS with an IRR adj of 2.31 (95% CI 2.09 to 2.56) when exposed to the highest level compared with the lowest. MPF also showed an exposure-response pattern, although less clear, with an IRR adj of 1.83 (1.68 to 1.98) for the highest compared with the lowest exposure level. ROM showed no clear pattern. Exposure-response patterns were different for men and women. Conclusions High levels of wrist movement were associated with an increased risk of CTS. Preventive strategies should be aimed at jobs with high levels of wrist movements such as cleaning, laundry work and slaughterhouse work.
KW - carpal tunnel syndrome
KW - electro-goniometry
KW - work-related carpal tunnel syndrome
KW - work-related disorders of the upper limb
KW - wrist movement
U2 - 10.1136/oemed-2018-105619
DO - 10.1136/oemed-2018-105619
M3 - Journal article
C2 - 31189693
AN - SCOPUS:85067287402
VL - 76
SP - 519
EP - 526
JO - Occupational and Environmental Medicine
JF - Occupational and Environmental Medicine
SN - 1351-0711
IS - 8
ER -
ID: 236317826