Neonatal levels of cytokines and risk of autism spectrum disorders: An exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Neonatal levels of cytokines and risk of autism spectrum disorders : An exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank. / Abdallah, Morsi; Larsen, Nanna ; Mortensen, Erik L; Atladóttir, Hjördis Ó; Nørgaard-Pedersen, Bent; Bonefeld-Jørgensen, Eva Cecilie; Grove, Jakob; Hougaard, David M.

In: Journal of Neuroimmunology, Vol. 252, No. 1-2, 2012, p. 75-82.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Abdallah, M, Larsen, N, Mortensen, EL, Atladóttir, HÓ, Nørgaard-Pedersen, B, Bonefeld-Jørgensen, EC, Grove, J & Hougaard, DM 2012, 'Neonatal levels of cytokines and risk of autism spectrum disorders: An exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank', Journal of Neuroimmunology, vol. 252, no. 1-2, pp. 75-82. https://doi.org/10.1016/j.jneuroim.2012.07.013

APA

Abdallah, M., Larsen, N., Mortensen, E. L., Atladóttir, H. Ó., Nørgaard-Pedersen, B., Bonefeld-Jørgensen, E. C., ... Hougaard, D. M. (2012). Neonatal levels of cytokines and risk of autism spectrum disorders: An exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank. Journal of Neuroimmunology, 252(1-2), 75-82. https://doi.org/10.1016/j.jneuroim.2012.07.013

Vancouver

Abdallah M, Larsen N, Mortensen EL, Atladóttir HÓ, Nørgaard-Pedersen B, Bonefeld-Jørgensen EC et al. Neonatal levels of cytokines and risk of autism spectrum disorders: An exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank. Journal of Neuroimmunology. 2012;252(1-2):75-82. https://doi.org/10.1016/j.jneuroim.2012.07.013

Author

Abdallah, Morsi ; Larsen, Nanna ; Mortensen, Erik L ; Atladóttir, Hjördis Ó ; Nørgaard-Pedersen, Bent ; Bonefeld-Jørgensen, Eva Cecilie ; Grove, Jakob ; Hougaard, David M. / Neonatal levels of cytokines and risk of autism spectrum disorders : An exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank. In: Journal of Neuroimmunology. 2012 ; Vol. 252, No. 1-2. pp. 75-82.

Bibtex

@article{a54f8800f05e45d2a722bedef72dcf0b,
title = "Neonatal levels of cytokines and risk of autism spectrum disorders: An exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank",
abstract = "The aim of the study was to analyze cytokine profiles in neonatal dried blood samples (n-DBSS) retrieved from The Danish Newborn Screening Biobank of children developing Autism Spectrum Disorders (ASD) later in life and controls. Samples of 359 ASD cases and 741 controls were analyzed using Luminex xMAP technology and clinical data were retrieved from nationwide registers. Findings showed that children developing ASD were more likely to have decreased levels of both T helper-1(Th-1)-like cytokines (i.e. IFN-¿) and Th-2like cytokines (i.e. IL-4, IL-10) which may suggest a depressed or hypoactive immune cell activity during neonatal period in ASD.",
author = "Morsi Abdallah and Nanna Larsen and Mortensen, {Erik L} and Atlad{\'o}ttir, {Hj{\"o}rdis {\'O}} and Bent N{\o}rgaard-Pedersen and Bonefeld-J{\o}rgensen, {Eva Cecilie} and Jakob Grove and Hougaard, {David M}",
note = "Copyright {\circledC} 2012 Elsevier B.V. All rights reserved.",
year = "2012",
doi = "10.1016/j.jneuroim.2012.07.013",
language = "English",
volume = "252",
pages = "75--82",
journal = "Journal of Neuroimmunology",
issn = "0165-5728",
publisher = "Elsevier",
number = "1-2",

}

RIS

TY - JOUR

T1 - Neonatal levels of cytokines and risk of autism spectrum disorders

T2 - An exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank

AU - Abdallah, Morsi

AU - Larsen, Nanna

AU - Mortensen, Erik L

AU - Atladóttir, Hjördis Ó

AU - Nørgaard-Pedersen, Bent

AU - Bonefeld-Jørgensen, Eva Cecilie

AU - Grove, Jakob

AU - Hougaard, David M

N1 - Copyright © 2012 Elsevier B.V. All rights reserved.

PY - 2012

Y1 - 2012

N2 - The aim of the study was to analyze cytokine profiles in neonatal dried blood samples (n-DBSS) retrieved from The Danish Newborn Screening Biobank of children developing Autism Spectrum Disorders (ASD) later in life and controls. Samples of 359 ASD cases and 741 controls were analyzed using Luminex xMAP technology and clinical data were retrieved from nationwide registers. Findings showed that children developing ASD were more likely to have decreased levels of both T helper-1(Th-1)-like cytokines (i.e. IFN-¿) and Th-2like cytokines (i.e. IL-4, IL-10) which may suggest a depressed or hypoactive immune cell activity during neonatal period in ASD.

AB - The aim of the study was to analyze cytokine profiles in neonatal dried blood samples (n-DBSS) retrieved from The Danish Newborn Screening Biobank of children developing Autism Spectrum Disorders (ASD) later in life and controls. Samples of 359 ASD cases and 741 controls were analyzed using Luminex xMAP technology and clinical data were retrieved from nationwide registers. Findings showed that children developing ASD were more likely to have decreased levels of both T helper-1(Th-1)-like cytokines (i.e. IFN-¿) and Th-2like cytokines (i.e. IL-4, IL-10) which may suggest a depressed or hypoactive immune cell activity during neonatal period in ASD.

U2 - 10.1016/j.jneuroim.2012.07.013

DO - 10.1016/j.jneuroim.2012.07.013

M3 - Journal article

VL - 252

SP - 75

EP - 82

JO - Journal of Neuroimmunology

JF - Journal of Neuroimmunology

SN - 0165-5728

IS - 1-2

ER -

ID: 41851478