Overdiagnosis in breast cancer screening

Overdiagnosis in breast cancer screening: The impact of study design and calculations

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Overdiagnosis in breast cancer screening : The impact of study design and calculations. / Lynge, Elsebeth; Beau, Anna-Belle; Christiansen, Peer; von Euler-Chelpin, My; Kroman, Niels; Njor, Sisse; Vejborg, Ilse.

In: European Journal of Cancer, Vol. 80, 07.2017, p. 26-29.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Lynge, E, Beau, A-B, Christiansen, P, von Euler-Chelpin, M, Kroman, N, Njor, S & Vejborg, I 2017, 'Overdiagnosis in breast cancer screening: The impact of study design and calculations', European Journal of Cancer, vol. 80, pp. 26-29. https://doi.org/10.1016/j.ejca.2017.04.018

APA

Lynge, E., Beau, A-B., Christiansen, P., von Euler-Chelpin, M., Kroman, N., Njor, S., & Vejborg, I. (2017). Overdiagnosis in breast cancer screening: The impact of study design and calculations. European Journal of Cancer, 80, 26-29. https://doi.org/10.1016/j.ejca.2017.04.018

Vancouver

Lynge E, Beau A-B, Christiansen P, von Euler-Chelpin M, Kroman N, Njor S et al. Overdiagnosis in breast cancer screening: The impact of study design and calculations. European Journal of Cancer. 2017 Jul;80:26-29. https://doi.org/10.1016/j.ejca.2017.04.018

Author

Lynge, Elsebeth ; Beau, Anna-Belle ; Christiansen, Peer ; von Euler-Chelpin, My ; Kroman, Niels ; Njor, Sisse ; Vejborg, Ilse. / Overdiagnosis in breast cancer screening : The impact of study design and calculations. In: European Journal of Cancer. 2017 ; Vol. 80. pp. 26-29.

Bibtex

@article{62e533d3195c4c63b3718738316315d7,

title = "Overdiagnosis in breast cancer screening: The impact of study design and calculations",

abstract = "Overdiagnosis in breast cancer screening is an important issue. A recent study from Denmark concluded that one in three breast cancers diagnosed in screening areas in women aged 50-69 years were overdiagnosed. The purpose of this short communication was to disentangle the study's methodology in order to evaluate the soundness of this conclusion. We found that both the use of absolute differences as opposed to ratios; the sole focus on non-advanced tumours and the crude allocation of tumours and person-years by screening history for women aged 70-84 years, all contributed to the very high estimate of overdiagnosis. Screening affects cohorts of screened women. Danish registers allow very accurate mapping of the fate of every woman. We should be past the phase where studies of overdiagnosis are based on the fixed age groups from routine statistics.",

author = "Elsebeth Lynge and Anna-Belle Beau and Peer Christiansen and {von Euler-Chelpin}, My and Niels Kroman and Sisse Njor and Ilse Vejborg",

year = "2017",

month = jul,

doi = "10.1016/j.ejca.2017.04.018",

language = "English",

volume = "80",

pages = "26--29",

journal = "European Journal of Cancer, Supplement",

issn = "0959-8049",

publisher = "Pergamon",

}

RIS

TY - JOUR

T1 - Overdiagnosis in breast cancer screening

T2 - The impact of study design and calculations

AU - Lynge, Elsebeth

AU - Beau, Anna-Belle

AU - Christiansen, Peer

AU - von Euler-Chelpin, My

AU - Kroman, Niels

AU - Njor, Sisse

AU - Vejborg, Ilse

PY - 2017/7

Y1 - 2017/7

N2 - Overdiagnosis in breast cancer screening is an important issue. A recent study from Denmark concluded that one in three breast cancers diagnosed in screening areas in women aged 50-69 years were overdiagnosed. The purpose of this short communication was to disentangle the study's methodology in order to evaluate the soundness of this conclusion. We found that both the use of absolute differences as opposed to ratios; the sole focus on non-advanced tumours and the crude allocation of tumours and person-years by screening history for women aged 70-84 years, all contributed to the very high estimate of overdiagnosis. Screening affects cohorts of screened women. Danish registers allow very accurate mapping of the fate of every woman. We should be past the phase where studies of overdiagnosis are based on the fixed age groups from routine statistics.

AB - Overdiagnosis in breast cancer screening is an important issue. A recent study from Denmark concluded that one in three breast cancers diagnosed in screening areas in women aged 50-69 years were overdiagnosed. The purpose of this short communication was to disentangle the study's methodology in order to evaluate the soundness of this conclusion. We found that both the use of absolute differences as opposed to ratios; the sole focus on non-advanced tumours and the crude allocation of tumours and person-years by screening history for women aged 70-84 years, all contributed to the very high estimate of overdiagnosis. Screening affects cohorts of screened women. Danish registers allow very accurate mapping of the fate of every woman. We should be past the phase where studies of overdiagnosis are based on the fixed age groups from routine statistics.

U2 - 10.1016/j.ejca.2017.04.018

DO - 10.1016/j.ejca.2017.04.018

M3 - Journal article

C2 - 28535494

VL - 80

SP - 26

EP - 29

JO - European Journal of Cancer, Supplement

JF - European Journal of Cancer, Supplement

SN - 0959-8049

ER -

ID: 178522693

Department of Public Health