Parental socioeconomic position and risk of ADHD in offspring: a cohort study of 9648 individuals in Denmark 1976–2013

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Parental socioeconomic position and risk of ADHD in offspring: a cohort study of 9648 individuals in Denmark 1976–2013. / Hegelund, Emilie Rune; Flensborg-Madsen, Trine; Vassard, Ditte; Niclasen, Janni; Mortensen, Erik Lykke.

In: European Child & Adolescent Psychiatry, Vol. 28, No. 5, 2019, p. 685-693.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Hegelund, ER, Flensborg-Madsen, T, Vassard, D, Niclasen, J & Mortensen, EL 2019, 'Parental socioeconomic position and risk of ADHD in offspring: a cohort study of 9648 individuals in Denmark 1976–2013', European Child & Adolescent Psychiatry, vol. 28, no. 5, pp. 685-693. https://doi.org/10.1007/s00787-018-1235-8

APA

Hegelund, E. R., Flensborg-Madsen, T., Vassard, D., Niclasen, J., & Mortensen, E. L. (2019). Parental socioeconomic position and risk of ADHD in offspring: a cohort study of 9648 individuals in Denmark 1976–2013. European Child & Adolescent Psychiatry, 28(5), 685-693. https://doi.org/10.1007/s00787-018-1235-8

Vancouver

Hegelund ER, Flensborg-Madsen T, Vassard D, Niclasen J, Mortensen EL. Parental socioeconomic position and risk of ADHD in offspring: a cohort study of 9648 individuals in Denmark 1976–2013. European Child & Adolescent Psychiatry. 2019;28(5):685-693. https://doi.org/10.1007/s00787-018-1235-8

Author

Hegelund, Emilie Rune ; Flensborg-Madsen, Trine ; Vassard, Ditte ; Niclasen, Janni ; Mortensen, Erik Lykke. / Parental socioeconomic position and risk of ADHD in offspring: a cohort study of 9648 individuals in Denmark 1976–2013. In: European Child & Adolescent Psychiatry. 2019 ; Vol. 28, No. 5. pp. 685-693.

Bibtex

@article{78b8b1681f3f4d1f802e899814ac10a4,
title = "Parental socioeconomic position and risk of ADHD in offspring: a cohort study of 9648 individuals in Denmark 1976–2013",
abstract = "The strength of the association between parental socioeconomic position (SEP) and risk of attention-deficit/hyperactivity disorder (ADHD) in offspring is found to vary substantially, perhaps due to the negligence of possible changes in parental life course SEP. The present study investigated the association between parental SEP in adulthood and risk of ADHD diagnosis in offspring and whether parental childhood SEP modified this association. The study population included 9648 live-born singletons followed in the Psychiatric Central Register from birth in 1976–1996 until 2013. Cox regression was used to estimate hazard ratios for ADHD diagnosis according to parental SEP in adulthood. The results showed that low parental SEP in adulthood was associated with higher risk of ADHD diagnosis in offspring, also after adjustment for possible confounders. Thus, offspring of parents with low SEP in adulthood had 4.52 (95% CI 2.81–7.26) times higher hazard of ADHD diagnosis compared with offspring of parents with high SEP in adulthood. Further, parental childhood SEP was found to modify the observed association. Thus, offspring of parents with downward social mobility from childhood to adulthood and offspring of parents with stable low SEP experienced the highest risk of ADHD diagnosis, followed by offspring of parents with upward social mobility, compared with offspring of parents with stable high SEP. The results suggest that it is important to take into account the possibility of social mobility as changes in parental life course SEP from childhood to adulthood seem to influence the risk of ADHD diagnosis in offspring.",
keywords = "ADHD, Cohort studies, Denmark, Socioeconomic factors",
author = "Hegelund, {Emilie Rune} and Trine Flensborg-Madsen and Ditte Vassard and Janni Niclasen and Mortensen, {Erik Lykke}",
year = "2019",
doi = "10.1007/s00787-018-1235-8",
language = "English",
volume = "28",
pages = "685--693",
journal = "European Child and Adolescent Psychiatry, Supplement",
issn = "1433-5719",
publisher = "Springer Medizin",
number = "5",

}

RIS

TY - JOUR

T1 - Parental socioeconomic position and risk of ADHD in offspring: a cohort study of 9648 individuals in Denmark 1976–2013

AU - Hegelund, Emilie Rune

AU - Flensborg-Madsen, Trine

AU - Vassard, Ditte

AU - Niclasen, Janni

AU - Mortensen, Erik Lykke

PY - 2019

Y1 - 2019

N2 - The strength of the association between parental socioeconomic position (SEP) and risk of attention-deficit/hyperactivity disorder (ADHD) in offspring is found to vary substantially, perhaps due to the negligence of possible changes in parental life course SEP. The present study investigated the association between parental SEP in adulthood and risk of ADHD diagnosis in offspring and whether parental childhood SEP modified this association. The study population included 9648 live-born singletons followed in the Psychiatric Central Register from birth in 1976–1996 until 2013. Cox regression was used to estimate hazard ratios for ADHD diagnosis according to parental SEP in adulthood. The results showed that low parental SEP in adulthood was associated with higher risk of ADHD diagnosis in offspring, also after adjustment for possible confounders. Thus, offspring of parents with low SEP in adulthood had 4.52 (95% CI 2.81–7.26) times higher hazard of ADHD diagnosis compared with offspring of parents with high SEP in adulthood. Further, parental childhood SEP was found to modify the observed association. Thus, offspring of parents with downward social mobility from childhood to adulthood and offspring of parents with stable low SEP experienced the highest risk of ADHD diagnosis, followed by offspring of parents with upward social mobility, compared with offspring of parents with stable high SEP. The results suggest that it is important to take into account the possibility of social mobility as changes in parental life course SEP from childhood to adulthood seem to influence the risk of ADHD diagnosis in offspring.

AB - The strength of the association between parental socioeconomic position (SEP) and risk of attention-deficit/hyperactivity disorder (ADHD) in offspring is found to vary substantially, perhaps due to the negligence of possible changes in parental life course SEP. The present study investigated the association between parental SEP in adulthood and risk of ADHD diagnosis in offspring and whether parental childhood SEP modified this association. The study population included 9648 live-born singletons followed in the Psychiatric Central Register from birth in 1976–1996 until 2013. Cox regression was used to estimate hazard ratios for ADHD diagnosis according to parental SEP in adulthood. The results showed that low parental SEP in adulthood was associated with higher risk of ADHD diagnosis in offspring, also after adjustment for possible confounders. Thus, offspring of parents with low SEP in adulthood had 4.52 (95% CI 2.81–7.26) times higher hazard of ADHD diagnosis compared with offspring of parents with high SEP in adulthood. Further, parental childhood SEP was found to modify the observed association. Thus, offspring of parents with downward social mobility from childhood to adulthood and offspring of parents with stable low SEP experienced the highest risk of ADHD diagnosis, followed by offspring of parents with upward social mobility, compared with offspring of parents with stable high SEP. The results suggest that it is important to take into account the possibility of social mobility as changes in parental life course SEP from childhood to adulthood seem to influence the risk of ADHD diagnosis in offspring.

KW - ADHD

KW - Cohort studies

KW - Denmark

KW - Socioeconomic factors

U2 - 10.1007/s00787-018-1235-8

DO - 10.1007/s00787-018-1235-8

M3 - Journal article

C2 - 30311007

VL - 28

SP - 685

EP - 693

JO - European Child and Adolescent Psychiatry, Supplement

JF - European Child and Adolescent Psychiatry, Supplement

SN - 1433-5719

IS - 5

ER -

ID: 203355363