Persistente fluorforbindelser reducerer immunfunktionen

Research output: Contribution to journalJournal articleResearchpeer-review

Carsten Heilmann, Lise Jensen, Pal Weihe, Flemming Nielsen, Lisbeth E. Knudsen, Esben Budtz-Jørgensen, Kåre Mølbak, Philippe Grandjean

Perfluorinated compounds are highly stable and useful industrial chemicals. Both perfluorooctane sulfonic acid and perfluorooctanoic acid cause immunotoxic effects in animal models at serum concentrations similar to human levels. In children who have undergone routine vaccinations, serum concentrations of these substances are inversely associated with concentrations of antibodies against diphtheria and tetanus. Prevention of such effects will require a decrease of exposure limits by at least 100-fold. Immunotoxicity is not included in routine testing of industrial chemicals but urgently needs attention.

Original languageDanish
JournalUgeskrift for Laeger
Volume176
Issue number7
Pages (from-to)660-663
Number of pages4
ISSN0041-5782
Publication statusPublished - 30 Mar 2015

ID: 137757241