Pharmacological characterization of social isolation-induced hyperactivity
Research output: Contribution to journal › Journal article › Research › peer-review
Social isolation (SI) of rats directly after weaning is a non-pharmacological, non-lesion animal model based on the neurodevelopmental hypothesis of schizophrenia. The model causes several neurobiological and behavioral alterations consistent with observations in schizophrenia.
|Number of pages||10|
|Publication status||Published - 2011|
- Acoustic Stimulation, Analysis of Variance, Animals, Animals, Newborn, Antipsychotic Agents, Behavior, Animal, Cohort Studies, Dose-Response Relationship, Drug, Hyperkinesis, Inhibition (Psychology), Male, Motor Activity, Psychoacoustics, Random Allocation, Rats, Social Isolation, Time Factors