Pharmacological characterization of social isolation-induced hyperactivity

Research output: Contribution to journalJournal articleResearchpeer-review

Katrine Fabricius, Lone Helboe, Anders Fink-Jensen, Gitta Wörtwein, Björn Steiniger-Brach

Social isolation (SI) of rats directly after weaning is a non-pharmacological, non-lesion animal model based on the neurodevelopmental hypothesis of schizophrenia. The model causes several neurobiological and behavioral alterations consistent with observations in schizophrenia.
Original languageEnglish
JournalPsychopharmacology
Volume215
Issue number2
Pages (from-to)257-66
Number of pages10
ISSN0033-3158
DOIs
Publication statusPublished - 2011

    Research areas

  • Acoustic Stimulation, Analysis of Variance, Animals, Animals, Newborn, Antipsychotic Agents, Behavior, Animal, Cohort Studies, Dose-Response Relationship, Drug, Hyperkinesis, Inhibition (Psychology), Male, Motor Activity, Psychoacoustics, Random Allocation, Rats, Social Isolation, Time Factors

ID: 37581644