Phthalate monoesters in perfusate from a dual placenta perfusion system, the placenta tissue and umbilical cord blood

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Phthalate monoesters in perfusate from a dual placenta perfusion system, the placenta tissue and umbilical cord blood. / Mose, Tina; Mortensen, Gerda K; Hedegaard, Morten; Knudsen, Lisbeth E.

In: Reproductive Toxicology, Vol. 23, No. 1, 2006, p. 83-91.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Mose, T, Mortensen, GK, Hedegaard, M & Knudsen, LE 2006, 'Phthalate monoesters in perfusate from a dual placenta perfusion system, the placenta tissue and umbilical cord blood', Reproductive Toxicology, vol. 23, no. 1, pp. 83-91. https://doi.org/10.1016/j.reprotox.2006.08.006

APA

Mose, T., Mortensen, G. K., Hedegaard, M., & Knudsen, L. E. (2006). Phthalate monoesters in perfusate from a dual placenta perfusion system, the placenta tissue and umbilical cord blood. Reproductive Toxicology, 23(1), 83-91. https://doi.org/10.1016/j.reprotox.2006.08.006

Vancouver

Mose T, Mortensen GK, Hedegaard M, Knudsen LE. Phthalate monoesters in perfusate from a dual placenta perfusion system, the placenta tissue and umbilical cord blood. Reproductive Toxicology. 2006;23(1):83-91. https://doi.org/10.1016/j.reprotox.2006.08.006

Author

Mose, Tina ; Mortensen, Gerda K ; Hedegaard, Morten ; Knudsen, Lisbeth E. / Phthalate monoesters in perfusate from a dual placenta perfusion system, the placenta tissue and umbilical cord blood. In: Reproductive Toxicology. 2006 ; Vol. 23, No. 1. pp. 83-91.

Bibtex

@article{40dd528020ec11ddbc23000ea68e967b,
title = "Phthalate monoesters in perfusate from a dual placenta perfusion system, the placenta tissue and umbilical cord blood",
abstract = "Fetal exposure to phthalates may be associated with adverse reproductive effects, including cryptorchidism and decreased semen quality. Information about human placental transfer is needed to qualify the hypotheses. A dual recirculating placenta perfusion system to monitor concentrations of eight phthalate monoesters in fetal and maternal perfusates was established. In addition to perfusate background measures of phthalate monoesters, the concentrations in umbilical cord plasma and placenta tissue were measured. Monomethyl phthalate (mMP), monoethyl phthalate (mEP), monobutyl phthalate (mBP), and mono (2-ethyl-hexyl) phthalate (mEHP) were detected in both maternal and fetal perfusate, demonstrating a release of compounds from tissue or blood to perfusates. The distribution of compounds between perfusate, umbilical cord plasma, and tissue was in accordance with the physical-chemical properties of the compounds. Results from the present study of compounds residing in the tissue are essential before studying human transplacental transfer, storage, and metabolism of selected phthalate monoesters.",
author = "Tina Mose and Mortensen, {Gerda K} and Morten Hedegaard and Knudsen, {Lisbeth E}",
note = "Keywords: Adult; Environmental Pollutants; Female; Fetal Blood; Humans; Maternal-Fetal Exchange; Perfusion; Phthalic Acids; Placenta; Pregnancy",
year = "2006",
doi = "10.1016/j.reprotox.2006.08.006",
language = "English",
volume = "23",
pages = "83--91",
journal = "Reproductive Toxicology",
issn = "0890-6238",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Phthalate monoesters in perfusate from a dual placenta perfusion system, the placenta tissue and umbilical cord blood

AU - Mose, Tina

AU - Mortensen, Gerda K

AU - Hedegaard, Morten

AU - Knudsen, Lisbeth E

N1 - Keywords: Adult; Environmental Pollutants; Female; Fetal Blood; Humans; Maternal-Fetal Exchange; Perfusion; Phthalic Acids; Placenta; Pregnancy

PY - 2006

Y1 - 2006

N2 - Fetal exposure to phthalates may be associated with adverse reproductive effects, including cryptorchidism and decreased semen quality. Information about human placental transfer is needed to qualify the hypotheses. A dual recirculating placenta perfusion system to monitor concentrations of eight phthalate monoesters in fetal and maternal perfusates was established. In addition to perfusate background measures of phthalate monoesters, the concentrations in umbilical cord plasma and placenta tissue were measured. Monomethyl phthalate (mMP), monoethyl phthalate (mEP), monobutyl phthalate (mBP), and mono (2-ethyl-hexyl) phthalate (mEHP) were detected in both maternal and fetal perfusate, demonstrating a release of compounds from tissue or blood to perfusates. The distribution of compounds between perfusate, umbilical cord plasma, and tissue was in accordance with the physical-chemical properties of the compounds. Results from the present study of compounds residing in the tissue are essential before studying human transplacental transfer, storage, and metabolism of selected phthalate monoesters.

AB - Fetal exposure to phthalates may be associated with adverse reproductive effects, including cryptorchidism and decreased semen quality. Information about human placental transfer is needed to qualify the hypotheses. A dual recirculating placenta perfusion system to monitor concentrations of eight phthalate monoesters in fetal and maternal perfusates was established. In addition to perfusate background measures of phthalate monoesters, the concentrations in umbilical cord plasma and placenta tissue were measured. Monomethyl phthalate (mMP), monoethyl phthalate (mEP), monobutyl phthalate (mBP), and mono (2-ethyl-hexyl) phthalate (mEHP) were detected in both maternal and fetal perfusate, demonstrating a release of compounds from tissue or blood to perfusates. The distribution of compounds between perfusate, umbilical cord plasma, and tissue was in accordance with the physical-chemical properties of the compounds. Results from the present study of compounds residing in the tissue are essential before studying human transplacental transfer, storage, and metabolism of selected phthalate monoesters.

U2 - 10.1016/j.reprotox.2006.08.006

DO - 10.1016/j.reprotox.2006.08.006

M3 - Journal article

C2 - 17049806

VL - 23

SP - 83

EP - 91

JO - Reproductive Toxicology

JF - Reproductive Toxicology

SN - 0890-6238

IS - 1

ER -

ID: 4039901