Pilocarpine iontophoresis test: an index of physiological sweat secretion?

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Pilocarpine iontophoresis test : an index of physiological sweat secretion? / Hjortskov, N; Jepsen, Leif; Nielsen, B; Juul, A; Skakkebaek, N E.

In: Clinical physiology (Oxford, England), Vol. 15, No. 4, 1995, p. 409-14.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Hjortskov, N, Jepsen, L, Nielsen, B, Juul, A & Skakkebaek, NE 1995, 'Pilocarpine iontophoresis test: an index of physiological sweat secretion?', Clinical physiology (Oxford, England), vol. 15, no. 4, pp. 409-14.

APA

Hjortskov, N., Jepsen, L., Nielsen, B., Juul, A., & Skakkebaek, N. E. (1995). Pilocarpine iontophoresis test: an index of physiological sweat secretion? Clinical physiology (Oxford, England), 15(4), 409-14.

Vancouver

Hjortskov N, Jepsen L, Nielsen B, Juul A, Skakkebaek NE. Pilocarpine iontophoresis test: an index of physiological sweat secretion? Clinical physiology (Oxford, England). 1995;15(4):409-14.

Author

Hjortskov, N ; Jepsen, Leif ; Nielsen, B ; Juul, A ; Skakkebaek, N E. / Pilocarpine iontophoresis test : an index of physiological sweat secretion?. In: Clinical physiology (Oxford, England). 1995 ; Vol. 15, No. 4. pp. 409-14.

Bibtex

@article{7718dc4cff4249e6846926274c17777f,
title = "Pilocarpine iontophoresis test: an index of physiological sweat secretion?",
abstract = "The pilocarpine iontophoresis test (P-test) is used as a predictor of the capacity to produce sweat. Therefore, we studied the reproducibility of this test in 12 normal subjects on 10 consecutive days. Furthermore, we determined whether the P-test reflects whole-body and regional sweat secretion during exercise in the heat. Finally, we determined whether the P-test stimulates the eccrine sweat glands to maximal sweat secretion. Six growth hormone-deficient (GHD) patients who are known to have decreased sweating, and 11 healthy control subjects were studied. To induce maximal sweat secretion, the patients exercised on a bicycle ergometer at a workload corresponding to 40{\%} of their maximal aerobic power (VO2max). The 11 healthy subjects exercised at a workload of 150 W. All subjects exercised for 60 min in ambient air at 35 degrees C, with 50{\%} relative humidity. The P-test showed a mean day-to-day variation of 20.8{\%} between individual subjects. There was a significant positive correlation between the P-test and regional sweat secretion (r2 = 0.74). The correlation coefficient (r2) was 0.50 for the correlation between the P-test and whole-body sweat secretion, and 0.52 for the correlation between regional sweat secretion and whole-body sweat secretion. We conclude that the pilocarpine iontophoresis test reflects heat- and exercise-induced sweating capacity. However, this test does not induce maximal sweating, and it cannot be used as a single reliable predictor of whole-body sweating, due to considerable day-to-day variation.",
author = "N Hjortskov and Leif Jepsen and B Nielsen and A Juul and Skakkebaek, {N E}",
year = "1995",
language = "English",
volume = "15",
pages = "409--14",
journal = "Clinical Physiology",
issn = "0144-5979",
publisher = "Blackwell Science Ltd.",
number = "4",

}

RIS

TY - JOUR

T1 - Pilocarpine iontophoresis test

T2 - an index of physiological sweat secretion?

AU - Hjortskov, N

AU - Jepsen, Leif

AU - Nielsen, B

AU - Juul, A

AU - Skakkebaek, N E

PY - 1995

Y1 - 1995

N2 - The pilocarpine iontophoresis test (P-test) is used as a predictor of the capacity to produce sweat. Therefore, we studied the reproducibility of this test in 12 normal subjects on 10 consecutive days. Furthermore, we determined whether the P-test reflects whole-body and regional sweat secretion during exercise in the heat. Finally, we determined whether the P-test stimulates the eccrine sweat glands to maximal sweat secretion. Six growth hormone-deficient (GHD) patients who are known to have decreased sweating, and 11 healthy control subjects were studied. To induce maximal sweat secretion, the patients exercised on a bicycle ergometer at a workload corresponding to 40% of their maximal aerobic power (VO2max). The 11 healthy subjects exercised at a workload of 150 W. All subjects exercised for 60 min in ambient air at 35 degrees C, with 50% relative humidity. The P-test showed a mean day-to-day variation of 20.8% between individual subjects. There was a significant positive correlation between the P-test and regional sweat secretion (r2 = 0.74). The correlation coefficient (r2) was 0.50 for the correlation between the P-test and whole-body sweat secretion, and 0.52 for the correlation between regional sweat secretion and whole-body sweat secretion. We conclude that the pilocarpine iontophoresis test reflects heat- and exercise-induced sweating capacity. However, this test does not induce maximal sweating, and it cannot be used as a single reliable predictor of whole-body sweating, due to considerable day-to-day variation.

AB - The pilocarpine iontophoresis test (P-test) is used as a predictor of the capacity to produce sweat. Therefore, we studied the reproducibility of this test in 12 normal subjects on 10 consecutive days. Furthermore, we determined whether the P-test reflects whole-body and regional sweat secretion during exercise in the heat. Finally, we determined whether the P-test stimulates the eccrine sweat glands to maximal sweat secretion. Six growth hormone-deficient (GHD) patients who are known to have decreased sweating, and 11 healthy control subjects were studied. To induce maximal sweat secretion, the patients exercised on a bicycle ergometer at a workload corresponding to 40% of their maximal aerobic power (VO2max). The 11 healthy subjects exercised at a workload of 150 W. All subjects exercised for 60 min in ambient air at 35 degrees C, with 50% relative humidity. The P-test showed a mean day-to-day variation of 20.8% between individual subjects. There was a significant positive correlation between the P-test and regional sweat secretion (r2 = 0.74). The correlation coefficient (r2) was 0.50 for the correlation between the P-test and whole-body sweat secretion, and 0.52 for the correlation between regional sweat secretion and whole-body sweat secretion. We conclude that the pilocarpine iontophoresis test reflects heat- and exercise-induced sweating capacity. However, this test does not induce maximal sweating, and it cannot be used as a single reliable predictor of whole-body sweating, due to considerable day-to-day variation.

M3 - Journal article

VL - 15

SP - 409

EP - 414

JO - Clinical Physiology

JF - Clinical Physiology

SN - 0144-5979

IS - 4

ER -

ID: 48486668