Placental perfusion - a human alternative

Research output: Contribution to journalJournal articlepeer-review

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Placental perfusion - a human alternative. / Mose, Tina; Knudsen, Lisbeth E.

In: ALTEX. Alternatives zu Tierexperimenten, Vol. 23 Suppl, 2006, p. 358-63.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Mose, T & Knudsen, LE 2006, 'Placental perfusion - a human alternative', ALTEX. Alternatives zu Tierexperimenten, vol. 23 Suppl, pp. 358-63.

APA

Mose, T., & Knudsen, L. E. (2006). Placental perfusion - a human alternative. ALTEX. Alternatives zu Tierexperimenten, 23 Suppl, 358-63.

Vancouver

Mose T, Knudsen LE. Placental perfusion - a human alternative. ALTEX. Alternatives zu Tierexperimenten. 2006;23 Suppl:358-63.

Author

Mose, Tina ; Knudsen, Lisbeth E. / Placental perfusion - a human alternative. In: ALTEX. Alternatives zu Tierexperimenten. 2006 ; Vol. 23 Suppl. pp. 358-63.

Bibtex

@article{826353d00cd111df825d000ea68e967b,
title = "Placental perfusion - a human alternative",
abstract = "Foetal exposures to environmental and medicinal products have impact on the growth of the foetus (e.g. cigarette smoke) and development of organs (e.g. methylmercury and Thalidomide). Perfusion studies of the human term placenta enable investigation of placental transport of chemical substances between the mother and foetus. Dual perfusion of a single cotyledon in the human placenta can contribute to a better understanding of the placental barrier, transport rate and mechanisms of different substances and placental metabolism. The perfusion system has recently been established in Copenhagen and represents a supplement and alternative to animal testing, bypassing the animal to human extrapolation. Placentas are readily obtainable from most births upon informed consent from the mothers and are considered a promising tissue alternative/supplement to animal experiments. The system is validated as a part of work package 2 of the integrated project ReProTect.",
author = "Tina Mose and Knudsen, {Lisbeth E}",
year = "2006",
language = "English",
volume = "23 Suppl",
pages = "358--63",
journal = "A L T E X. Alternatives to Animal Experimentation",
issn = "1868-596X",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - Placental perfusion - a human alternative

AU - Mose, Tina

AU - Knudsen, Lisbeth E

PY - 2006

Y1 - 2006

N2 - Foetal exposures to environmental and medicinal products have impact on the growth of the foetus (e.g. cigarette smoke) and development of organs (e.g. methylmercury and Thalidomide). Perfusion studies of the human term placenta enable investigation of placental transport of chemical substances between the mother and foetus. Dual perfusion of a single cotyledon in the human placenta can contribute to a better understanding of the placental barrier, transport rate and mechanisms of different substances and placental metabolism. The perfusion system has recently been established in Copenhagen and represents a supplement and alternative to animal testing, bypassing the animal to human extrapolation. Placentas are readily obtainable from most births upon informed consent from the mothers and are considered a promising tissue alternative/supplement to animal experiments. The system is validated as a part of work package 2 of the integrated project ReProTect.

AB - Foetal exposures to environmental and medicinal products have impact on the growth of the foetus (e.g. cigarette smoke) and development of organs (e.g. methylmercury and Thalidomide). Perfusion studies of the human term placenta enable investigation of placental transport of chemical substances between the mother and foetus. Dual perfusion of a single cotyledon in the human placenta can contribute to a better understanding of the placental barrier, transport rate and mechanisms of different substances and placental metabolism. The perfusion system has recently been established in Copenhagen and represents a supplement and alternative to animal testing, bypassing the animal to human extrapolation. Placentas are readily obtainable from most births upon informed consent from the mothers and are considered a promising tissue alternative/supplement to animal experiments. The system is validated as a part of work package 2 of the integrated project ReProTect.

M3 - Journal article

C2 - 17492213

VL - 23 Suppl

SP - 358

EP - 363

JO - A L T E X. Alternatives to Animal Experimentation

JF - A L T E X. Alternatives to Animal Experimentation

SN - 1868-596X

ER -

ID: 17273240