Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury

Research output: Contribution to journalJournal articlepeer-review

Standard

Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury. / Timmermann, Clara Amalie Gade; Choi, Anna L.; Petersen, Maria Skaalum; Nielsen, Flemming; Budtz-Jørgensen, Esben; Weihe, Pál; Grandjean, Philippe.

In: International Journal of Circumpolar Health, Vol. 76, No. 1, 1406234, 2017, p. 1-8.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Timmermann, CAG, Choi, AL, Petersen, MS, Nielsen, F, Budtz-Jørgensen, E, Weihe, P & Grandjean, P 2017, 'Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury', International Journal of Circumpolar Health, vol. 76, no. 1, 1406234, pp. 1-8. https://doi.org/10.1080/22423982.2017.1406234

APA

Timmermann, C. A. G., Choi, A. L., Petersen, M. S., Nielsen, F., Budtz-Jørgensen, E., Weihe, P., & Grandjean, P. (2017). Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury. International Journal of Circumpolar Health, 76(1), 1-8. [1406234]. https://doi.org/10.1080/22423982.2017.1406234

Vancouver

Timmermann CAG, Choi AL, Petersen MS, Nielsen F, Budtz-Jørgensen E, Weihe P et al. Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury. International Journal of Circumpolar Health. 2017;76(1):1-8. 1406234. https://doi.org/10.1080/22423982.2017.1406234

Author

Timmermann, Clara Amalie Gade ; Choi, Anna L. ; Petersen, Maria Skaalum ; Nielsen, Flemming ; Budtz-Jørgensen, Esben ; Weihe, Pál ; Grandjean, Philippe. / Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury. In: International Journal of Circumpolar Health. 2017 ; Vol. 76, No. 1. pp. 1-8.

Bibtex

@article{2d27491662474c959475b6bd83eb5d64,
title = "Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury",
abstract = "This study was undertaken to assess the potential impact of maternal exposures to polychlorinated biphenyl (PCB), dichlorodiphenyl dichloroethylene (DDE) and methylmercury on the secondary sex ratios (the ratio of male to female live births) over a span of 23 years. The study includes prospective data from three Faroese birth cohorts, with a total of 2,152 healthy mother-child dyads recruited between 1986 and 2009. The Faroe Islands is a subarctic fishing community, where pilot whale meat and blubber are part of the traditional marine diet. Exposures were measured in maternal hair, serum or umbilical cord blood. Confounder adjusted logistic regression models were used to assess the associations between maternal exposures and the secondary sex ratio. A doubling in ΣPCB, p,p'-DDE and mercury concentrations were associated with increased odds by 8% (95% CI = 0-16%), 7% (95% CI = 0-14%) and 9% (95% CI = 2-17%), respectively, of giving birth to a boy. In conclusion, maternal exposure to ΣPCB, DDE and methylmercury was associated with a slightly increased secondary sex ratio. The impact of paternal exposures could not be taken into account and deserves attention.",
keywords = "Journal Article",
author = "Timmermann, {Clara Amalie Gade} and Choi, {Anna L.} and Petersen, {Maria Skaalum} and Flemming Nielsen and Esben Budtz-J{\o}rgensen and P{\'a}l Weihe and Philippe Grandjean",
year = "2017",
doi = "10.1080/22423982.2017.1406234",
language = "English",
volume = "76",
pages = "1--8",
journal = "International Journal of Circumpolar Health",
issn = "1239-9736",
publisher = "International Association of Circumpolar Health Publishers",
number = "1",

}

RIS

TY - JOUR

T1 - Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury

AU - Timmermann, Clara Amalie Gade

AU - Choi, Anna L.

AU - Petersen, Maria Skaalum

AU - Nielsen, Flemming

AU - Budtz-Jørgensen, Esben

AU - Weihe, Pál

AU - Grandjean, Philippe

PY - 2017

Y1 - 2017

N2 - This study was undertaken to assess the potential impact of maternal exposures to polychlorinated biphenyl (PCB), dichlorodiphenyl dichloroethylene (DDE) and methylmercury on the secondary sex ratios (the ratio of male to female live births) over a span of 23 years. The study includes prospective data from three Faroese birth cohorts, with a total of 2,152 healthy mother-child dyads recruited between 1986 and 2009. The Faroe Islands is a subarctic fishing community, where pilot whale meat and blubber are part of the traditional marine diet. Exposures were measured in maternal hair, serum or umbilical cord blood. Confounder adjusted logistic regression models were used to assess the associations between maternal exposures and the secondary sex ratio. A doubling in ΣPCB, p,p'-DDE and mercury concentrations were associated with increased odds by 8% (95% CI = 0-16%), 7% (95% CI = 0-14%) and 9% (95% CI = 2-17%), respectively, of giving birth to a boy. In conclusion, maternal exposure to ΣPCB, DDE and methylmercury was associated with a slightly increased secondary sex ratio. The impact of paternal exposures could not be taken into account and deserves attention.

AB - This study was undertaken to assess the potential impact of maternal exposures to polychlorinated biphenyl (PCB), dichlorodiphenyl dichloroethylene (DDE) and methylmercury on the secondary sex ratios (the ratio of male to female live births) over a span of 23 years. The study includes prospective data from three Faroese birth cohorts, with a total of 2,152 healthy mother-child dyads recruited between 1986 and 2009. The Faroe Islands is a subarctic fishing community, where pilot whale meat and blubber are part of the traditional marine diet. Exposures were measured in maternal hair, serum or umbilical cord blood. Confounder adjusted logistic regression models were used to assess the associations between maternal exposures and the secondary sex ratio. A doubling in ΣPCB, p,p'-DDE and mercury concentrations were associated with increased odds by 8% (95% CI = 0-16%), 7% (95% CI = 0-14%) and 9% (95% CI = 2-17%), respectively, of giving birth to a boy. In conclusion, maternal exposure to ΣPCB, DDE and methylmercury was associated with a slightly increased secondary sex ratio. The impact of paternal exposures could not be taken into account and deserves attention.

KW - Journal Article

U2 - 10.1080/22423982.2017.1406234

DO - 10.1080/22423982.2017.1406234

M3 - Journal article

C2 - 29195489

VL - 76

SP - 1

EP - 8

JO - International Journal of Circumpolar Health

JF - International Journal of Circumpolar Health

SN - 1239-9736

IS - 1

M1 - 1406234

ER -

ID: 189104731