Urinary Bisphenol A, F and S Levels and Semen Quality in Young Adult Danish Men
Research output: Contribution to journal › Journal article › peer-review
Documents
- Urinary Bisphenol A, F and S Levels and Semen Quality in Young Adult Danish Men
Final published version, 348 KB, PDF document
Bisphenol A (BPA) is considered an endocrine disruptor and has been associated with deleterious effects on spermatogenesis and male fertility. Bisphenol F (BPF) and S (BPS) are structurally similar to BPA, but knowledge of their effects on male fertility remains limited. In this cross-sectional study, we investigated the associations between exposure to BPA, BPF, and BPS and semen quality in 556 men 18-20 years of age from the Fetal Programming of Semen Quality (FEPOS) cohort. A urine sample was collected from each participant for determination of BPA, BPF, and BPS concentrations while a semen sample was collected to determine ejaculate volume, sperm concentration, total sperm count, sperm motility, and sperm morphology. Associations between urinary bisphenol levels (continuous and quartile-divided) and semen characteristics were estimated using a negative binomial regression model adjusting for urine creatinine concentration, alcohol intake, smoking status, body mass index (BMI), fever, sexual abstinence time, maternal pre-pregnancy BMI, and first trimester smoking, and highest parental education during first trimester. We found no associations between urinary bisphenol of semen quality in a sample of young men from the general Danish population.
Original language | English |
---|---|
Article number | 1742 |
Journal | International Journal of Environmental Research and Public Health |
Volume | 18 |
Issue number | 4 |
Number of pages | 12 |
ISSN | 1661-7827 |
DOIs | |
Publication status | Published - 2021 |
- bisphenol, endocrine disruptor, epidemiology, male fertility, semen quality
Research areas
Number of downloads are based on statistics from Google Scholar and www.ku.dk
ID: 258613612