Health effects of particles

The research area covers exposure to and effects of particles from outdoor and indoor air pollution, as well as engineered, including medical, nanoparticles.

Research activities span the entire hierarchy of techniques from experimental models such as synthetic membranes, organotypic cell cultures and transgenic animals, via the use of biomarkers and functional measures in populations at controlled exposure and interventions, to register-based epidemiology at the aggregate level.

Particular focus areas are: mechanisms associated with oxidative stress-related genotoxic and vascular effects and on vulnerable groups, such as the genetically disposed, the foetus, children and elderly people with and without diabetes and/or obesity, as well as regulation of defence mechanisms such as DNA repair. Part of the research takes place within the AIRPOLIFE, WOODUSE and REBECA research networks.