Assessment of subjective and objective cognitive function in bipolar disorder: Correlations, predictors and the relation to psychosocial function

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Assessment of subjective and objective cognitive function in bipolar disorder : Correlations, predictors and the relation to psychosocial function. / Demant, Kirsa M; Vinberg, Maj; Kessing, Lars V; Miskowiak, Kamilla W.

In: Psychiatry Research, Vol. 229, No. 1-2, 30.09.2015, p. 565-71.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Demant, KM, Vinberg, M, Kessing, LV & Miskowiak, KW 2015, 'Assessment of subjective and objective cognitive function in bipolar disorder: Correlations, predictors and the relation to psychosocial function', Psychiatry Research, vol. 229, no. 1-2, pp. 565-71. https://doi.org/10.1016/j.psychres.2015.05.022

APA

Demant, K. M., Vinberg, M., Kessing, L. V., & Miskowiak, K. W. (2015). Assessment of subjective and objective cognitive function in bipolar disorder: Correlations, predictors and the relation to psychosocial function. Psychiatry Research, 229(1-2), 565-71. https://doi.org/10.1016/j.psychres.2015.05.022

Vancouver

Demant KM, Vinberg M, Kessing LV, Miskowiak KW. Assessment of subjective and objective cognitive function in bipolar disorder: Correlations, predictors and the relation to psychosocial function. Psychiatry Research. 2015 Sep 30;229(1-2):565-71. https://doi.org/10.1016/j.psychres.2015.05.022

Author

Demant, Kirsa M ; Vinberg, Maj ; Kessing, Lars V ; Miskowiak, Kamilla W. / Assessment of subjective and objective cognitive function in bipolar disorder : Correlations, predictors and the relation to psychosocial function. In: Psychiatry Research. 2015 ; Vol. 229, No. 1-2. pp. 565-71.

Bibtex

@article{b8a38602842c404498ddcf730e35bc3e,
title = "Assessment of subjective and objective cognitive function in bipolar disorder: Correlations, predictors and the relation to psychosocial function",
abstract = "Cognitive dysfunction is prevalent in bipolar disorder (BD). However, the evidence regarding the association between subjective cognitive complaints, objective cognitive performance and psychosocial function is sparse and inconsistent. Seventy seven patients with bipolar disorder who presented cognitive complaints underwent assessment of objective and subjective cognitive function and psychosocial functioning as part of their participation in two clinical trials. We investigated the association between global and domain-specific objective and subjective cognitive function and between global cognitive function and psychosocial function. We also identified clinical variables that predicted objective and subjective cognitive function and psychosocial functioning. There was a correlation between global subjective and objective measures of cognitive dysfunction but not within the individual cognitive domains. However, the correlation was weak, suggesting that cognitive complaints are not an assay of cognition per se. Self-rated psychosocial difficulties were associated with subjective (but not objective) cognitive impairment and both subjective cognitive and psychosocial difficulties were predicted by depressive symptoms. Our findings indicate that adequate assessment of cognition in the clinical treatment of BD and in drug trials targeting cognition requires implementation of not only subjective measures but also of objective neuropsychological tests.",
keywords = "Adult, Bipolar Disorder, Cognition, Cognition Disorders, Cohort Studies, Depression, Executive Function, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Predictive Value of Tests, Psychology",
author = "Demant, {Kirsa M} and Maj Vinberg and Kessing, {Lars V} and Miskowiak, {Kamilla W}",
note = "Copyright {\circledC} 2015 Elsevier Ireland Ltd. All rights reserved.",
year = "2015",
month = "9",
day = "30",
doi = "10.1016/j.psychres.2015.05.022",
language = "English",
volume = "229",
pages = "565--71",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",
number = "1-2",

}

RIS

TY - JOUR

T1 - Assessment of subjective and objective cognitive function in bipolar disorder

T2 - Correlations, predictors and the relation to psychosocial function

AU - Demant, Kirsa M

AU - Vinberg, Maj

AU - Kessing, Lars V

AU - Miskowiak, Kamilla W

N1 - Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

PY - 2015/9/30

Y1 - 2015/9/30

N2 - Cognitive dysfunction is prevalent in bipolar disorder (BD). However, the evidence regarding the association between subjective cognitive complaints, objective cognitive performance and psychosocial function is sparse and inconsistent. Seventy seven patients with bipolar disorder who presented cognitive complaints underwent assessment of objective and subjective cognitive function and psychosocial functioning as part of their participation in two clinical trials. We investigated the association between global and domain-specific objective and subjective cognitive function and between global cognitive function and psychosocial function. We also identified clinical variables that predicted objective and subjective cognitive function and psychosocial functioning. There was a correlation between global subjective and objective measures of cognitive dysfunction but not within the individual cognitive domains. However, the correlation was weak, suggesting that cognitive complaints are not an assay of cognition per se. Self-rated psychosocial difficulties were associated with subjective (but not objective) cognitive impairment and both subjective cognitive and psychosocial difficulties were predicted by depressive symptoms. Our findings indicate that adequate assessment of cognition in the clinical treatment of BD and in drug trials targeting cognition requires implementation of not only subjective measures but also of objective neuropsychological tests.

AB - Cognitive dysfunction is prevalent in bipolar disorder (BD). However, the evidence regarding the association between subjective cognitive complaints, objective cognitive performance and psychosocial function is sparse and inconsistent. Seventy seven patients with bipolar disorder who presented cognitive complaints underwent assessment of objective and subjective cognitive function and psychosocial functioning as part of their participation in two clinical trials. We investigated the association between global and domain-specific objective and subjective cognitive function and between global cognitive function and psychosocial function. We also identified clinical variables that predicted objective and subjective cognitive function and psychosocial functioning. There was a correlation between global subjective and objective measures of cognitive dysfunction but not within the individual cognitive domains. However, the correlation was weak, suggesting that cognitive complaints are not an assay of cognition per se. Self-rated psychosocial difficulties were associated with subjective (but not objective) cognitive impairment and both subjective cognitive and psychosocial difficulties were predicted by depressive symptoms. Our findings indicate that adequate assessment of cognition in the clinical treatment of BD and in drug trials targeting cognition requires implementation of not only subjective measures but also of objective neuropsychological tests.

KW - Adult

KW - Bipolar Disorder

KW - Cognition

KW - Cognition Disorders

KW - Cohort Studies

KW - Depression

KW - Executive Function

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Neuropsychological Tests

KW - Predictive Value of Tests

KW - Psychology

U2 - 10.1016/j.psychres.2015.05.022

DO - 10.1016/j.psychres.2015.05.022

M3 - Journal article

C2 - 26073281

VL - 229

SP - 565

EP - 571

JO - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

IS - 1-2

ER -

ID: 162339709