Cumplimiento de las recomendaciones internacionales en la lucha contra las resistencias bacterianas: Diferencias relevantes entre elconsumo ambulatorio en España y Dinamarca

Research output: Contribution to journalJournal articleResearchpeer-review

Sara Malo, Mara Jose Rabanaque, Lars Bjerrum

OBJECTIVE:
Increasing antibiotic resistance represents a major public health threat that jeopardises the future treatment of bacterial infections. This study aims to describe the adherence to recommendations proposed by the World Health Organization (WHO) Advisory Group on Integrated Surveillance of Antimicrobial Resistance (AGISAR), in Spain and Denmark, and to analyse the relation between the outpatient use of Critically Important Antimicrobials (CIA) and the bacterial resistance rates to these agents.
METHODS:
The Antimicrobial consumption interactive database (ESAC-Net) and Antimicrobial resistance interactive database (EARS-Net) provided data on outpatient use (2010-2013) of CIA (fluoroquinolones, macrolides, and 3rd and 4th generation cephalosporins) and the percentages of isolates of the main pathogens causing serious infections, resistant to these agents.
RESULTS:
The use of cephalosporins and fluoroquinolones, as well as the percentage of bacteria resistant, is higher in Spain than in Denmark. Although consumption of macrolides in both countries is similar, the proportion of Streptococcus pneumoniae resistant to macrolides is significantly higher in Spain.
CONCLUSIONS:
The high outpatient consumption of CIA agents in Spain deviates substantially from the WHO recommendations. Moreover, it has the effect of elevated rates of antimicrobial resistance, that are lower in Denmark
Original languageSpanish
JournalRevista Espanola de Quimioterapia
Volume29
Issue number1
Pages (from-to)40-43
Number of pages4
ISSN0214-3429
Publication statusPublished - Feb 2016

Bibliographical note

PMID: 26809795

    Research areas

  • Antibiotics, CIA agents, international comparison, bacterial resistance, compliance with recommendations

ID: 163863098