Decreasing incidence of foot ulcer among patients with type 1 and type 2 diabetes in the period 2001-2014

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Decreasing incidence of foot ulcer among patients with type 1 and type 2 diabetes in the period 2001-2014. / Rasmussen, A.; Almdal, T.; Nielsen, A. Anker; Nielsen, K. E.; Jørgensen, M. E.; Hangaard, S.; Siersma, V.; Holstein, P. E.

In: Diabetes Research and Clinical Practice, Vol. 130, 08.2017, p. 221-228.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Rasmussen, A, Almdal, T, Nielsen, AA, Nielsen, KE, Jørgensen, ME, Hangaard, S, Siersma, V & Holstein, PE 2017, 'Decreasing incidence of foot ulcer among patients with type 1 and type 2 diabetes in the period 2001-2014', Diabetes Research and Clinical Practice, vol. 130, pp. 221-228. https://doi.org/10.1016/j.diabres.2017.05.025

APA

Rasmussen, A., Almdal, T., Nielsen, A. A., Nielsen, K. E., Jørgensen, M. E., Hangaard, S., ... Holstein, P. E. (2017). Decreasing incidence of foot ulcer among patients with type 1 and type 2 diabetes in the period 2001-2014. Diabetes Research and Clinical Practice, 130, 221-228. https://doi.org/10.1016/j.diabres.2017.05.025

Vancouver

Rasmussen A, Almdal T, Nielsen AA, Nielsen KE, Jørgensen ME, Hangaard S et al. Decreasing incidence of foot ulcer among patients with type 1 and type 2 diabetes in the period 2001-2014. Diabetes Research and Clinical Practice. 2017 Aug;130:221-228. https://doi.org/10.1016/j.diabres.2017.05.025

Author

Rasmussen, A. ; Almdal, T. ; Nielsen, A. Anker ; Nielsen, K. E. ; Jørgensen, M. E. ; Hangaard, S. ; Siersma, V. ; Holstein, P. E. / Decreasing incidence of foot ulcer among patients with type 1 and type 2 diabetes in the period 2001-2014. In: Diabetes Research and Clinical Practice. 2017 ; Vol. 130. pp. 221-228.

Bibtex

@article{d5613ca2a597462eb9a6518745b0423f,
title = "Decreasing incidence of foot ulcer among patients with type 1 and type 2 diabetes in the period 2001-2014",
abstract = "Aim: Diabetic foot ulcer (DFU) is a serious complication to diabetes. The aim was to study the incidence of first DFU among patients with type 1 (T1DM) and type 2 diabetes (T2DM), stratified according to etiology: neuropathic, neuro-ischemic or ischemic, over a period of 14 years (2001–2014).Methods: DFU incidence rates were calculated from electronic patient record data from patients with T1DM and complicated T2DM from a large specialized diabetes hospital with a multidisciplinary foot clinic in Denmark. Poisson regression was used to model incidence of first DFU according to calendar year, diabetes type and etiology.Results: Among 5640 patients with T1DM 255 developed a DFU, corresponding to an incidence of 5.8 (95{\%} confidence interval (95{\%}CI) 5.1–6.5) per 1000 patient years; this incidence dropped from 8.1 (95{\%}CI 5.4–11.9) per 1000 patient years in 2002 to 2.6 (95{\%}CI 1.3–5.3) in 2014 (p = 0.0059). Among 6953 patients with T2DM 310 developed a DFU, corresponding to an incidence of 11.3 (95{\%}CI 10.1–12.6) per 1000 patient years; this incidence dropped from 17.0 (95{\%}CI 12.2–23.8) per 1000 patient years in 2002 to 8.7 (95{\%}CI 5.3–14.1) per 1000 patient year (p = 0.0260) in 2014.Conclusion: The incidence of DFU has decreased substantially in T1DM as well as in T2DM. This change was driven by a decrease in incidence of neuropathic ulcers.",
keywords = "Foot ulcer, Peripheral neuropathy, Diabetes complications, Type 1 diabetes, Type 2 diabetes",
author = "A. Rasmussen and T. Almdal and Nielsen, {A. Anker} and Nielsen, {K. E.} and J{\o}rgensen, {M. E.} and S. Hangaard and V. Siersma and Holstein, {P. E.}",
year = "2017",
month = "8",
doi = "10.1016/j.diabres.2017.05.025",
language = "English",
volume = "130",
pages = "221--228",
journal = "Diabetes Research and Clinical Practice",
issn = "0168-8227",
publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Decreasing incidence of foot ulcer among patients with type 1 and type 2 diabetes in the period 2001-2014

AU - Rasmussen, A.

AU - Almdal, T.

AU - Nielsen, A. Anker

AU - Nielsen, K. E.

AU - Jørgensen, M. E.

AU - Hangaard, S.

AU - Siersma, V.

AU - Holstein, P. E.

PY - 2017/8

Y1 - 2017/8

N2 - Aim: Diabetic foot ulcer (DFU) is a serious complication to diabetes. The aim was to study the incidence of first DFU among patients with type 1 (T1DM) and type 2 diabetes (T2DM), stratified according to etiology: neuropathic, neuro-ischemic or ischemic, over a period of 14 years (2001–2014).Methods: DFU incidence rates were calculated from electronic patient record data from patients with T1DM and complicated T2DM from a large specialized diabetes hospital with a multidisciplinary foot clinic in Denmark. Poisson regression was used to model incidence of first DFU according to calendar year, diabetes type and etiology.Results: Among 5640 patients with T1DM 255 developed a DFU, corresponding to an incidence of 5.8 (95% confidence interval (95%CI) 5.1–6.5) per 1000 patient years; this incidence dropped from 8.1 (95%CI 5.4–11.9) per 1000 patient years in 2002 to 2.6 (95%CI 1.3–5.3) in 2014 (p = 0.0059). Among 6953 patients with T2DM 310 developed a DFU, corresponding to an incidence of 11.3 (95%CI 10.1–12.6) per 1000 patient years; this incidence dropped from 17.0 (95%CI 12.2–23.8) per 1000 patient years in 2002 to 8.7 (95%CI 5.3–14.1) per 1000 patient year (p = 0.0260) in 2014.Conclusion: The incidence of DFU has decreased substantially in T1DM as well as in T2DM. This change was driven by a decrease in incidence of neuropathic ulcers.

AB - Aim: Diabetic foot ulcer (DFU) is a serious complication to diabetes. The aim was to study the incidence of first DFU among patients with type 1 (T1DM) and type 2 diabetes (T2DM), stratified according to etiology: neuropathic, neuro-ischemic or ischemic, over a period of 14 years (2001–2014).Methods: DFU incidence rates were calculated from electronic patient record data from patients with T1DM and complicated T2DM from a large specialized diabetes hospital with a multidisciplinary foot clinic in Denmark. Poisson regression was used to model incidence of first DFU according to calendar year, diabetes type and etiology.Results: Among 5640 patients with T1DM 255 developed a DFU, corresponding to an incidence of 5.8 (95% confidence interval (95%CI) 5.1–6.5) per 1000 patient years; this incidence dropped from 8.1 (95%CI 5.4–11.9) per 1000 patient years in 2002 to 2.6 (95%CI 1.3–5.3) in 2014 (p = 0.0059). Among 6953 patients with T2DM 310 developed a DFU, corresponding to an incidence of 11.3 (95%CI 10.1–12.6) per 1000 patient years; this incidence dropped from 17.0 (95%CI 12.2–23.8) per 1000 patient years in 2002 to 8.7 (95%CI 5.3–14.1) per 1000 patient year (p = 0.0260) in 2014.Conclusion: The incidence of DFU has decreased substantially in T1DM as well as in T2DM. This change was driven by a decrease in incidence of neuropathic ulcers.

KW - Foot ulcer

KW - Peripheral neuropathy

KW - Diabetes complications

KW - Type 1 diabetes

KW - Type 2 diabetes

U2 - 10.1016/j.diabres.2017.05.025

DO - 10.1016/j.diabres.2017.05.025

M3 - Journal article

VL - 130

SP - 221

EP - 228

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

SN - 0168-8227

ER -

ID: 188452836