Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity

Research output: Contribution to journalJournal articleResearchpeer-review

G Andersen, L Wegner, K Yanagisawa, C S Rose, J Lin, C Glümer, T Drivsholm, K Borch-Johnsen, T Jørgensen, T Hansen, B M Spiegelman, O Pedersen

Peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) is a recently identified homologue of the tissue specific coactivator PGC-1alpha, a coactivator of transcription factors such as the peroxisome proliferators activated receptors and nuclear respiratory factors. PGC-1alpha is involved in adipogenesis, mitochondrial biogenesis, fatty acid beta oxidation, and hepatic gluconeogenesis.
Original languageEnglish
JournalJournal of Medical Genetics
Issue number5
Pages (from-to)402-7
Number of pages6
Publication statusPublished - 1 May 2005

    Research areas

  • Aged, Carrier Proteins, DNA Mutational Analysis, Denmark, Diabetes Mellitus, Type 2, Gene Frequency, Genetic Testing, Genetic Variation, Genotype, Glucose, Humans, Linkage Disequilibrium, Middle Aged, Mutation, Obesity

ID: 33030532