Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity

Research output: Contribution to journalJournal articleResearchpeer-review

  • G Andersen
  • L Wegner
  • K Yanagisawa
  • C S Rose
  • J Lin
  • C Glümer
  • Drivsholm, Thomas
  • K Borch-Johnsen
  • T Jørgensen
  • T Hansen
  • B M Spiegelman
  • O Pedersen
Peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) is a recently identified homologue of the tissue specific coactivator PGC-1alpha, a coactivator of transcription factors such as the peroxisome proliferators activated receptors and nuclear respiratory factors. PGC-1alpha is involved in adipogenesis, mitochondrial biogenesis, fatty acid beta oxidation, and hepatic gluconeogenesis.
Original languageEnglish
JournalJournal of Medical Genetics
Issue number5
Pages (from-to)402-7
Number of pages6
Publication statusPublished - 1 May 2005

    Research areas

  • Aged, Carrier Proteins, DNA Mutational Analysis, Denmark, Diabetes Mellitus, Type 2, Gene Frequency, Genetic Testing, Genetic Variation, Genotype, Glucose, Humans, Linkage Disequilibrium, Middle Aged, Mutation, Obesity

ID: 33030532