Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity
Research output: Contribution to journal › Journal article › Research › peer-review
G Andersen, L Wegner, K Yanagisawa, C S Rose, J Lin, C Glümer, T Drivsholm, K Borch-Johnsen, T Jørgensen, T Hansen, B M Spiegelman, O Pedersen
Peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) is a recently identified homologue of the tissue specific coactivator PGC-1alpha, a coactivator of transcription factors such as the peroxisome proliferators activated receptors and nuclear respiratory factors. PGC-1alpha is involved in adipogenesis, mitochondrial biogenesis, fatty acid beta oxidation, and hepatic gluconeogenesis.
|Journal||Journal of Medical Genetics|
|Number of pages||6|
|Publication status||Published - 1 May 2005|
- Aged, Carrier Proteins, DNA Mutational Analysis, Denmark, Diabetes Mellitus, Type 2, Gene Frequency, Genetic Testing, Genetic Variation, Genotype, Glucose, Humans, Linkage Disequilibrium, Middle Aged, Mutation, Obesity