The development of multimorbidity during 16 years after diagnosis of type 2 diabetes

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

The development of multimorbidity during 16 years after diagnosis of type 2 diabetes. / Pouplier, Sandra; Olsen, Maria Åhlander; Willadsen, Tora Grauers; Sandholdt, Håkon; Siersma, Volkert; Andersen, Christen Lykkegaard; Olivarius, Niels de Fine.

In: Journal of Comorbidity, Vol. 8, No. 1, 2018, p. 1-9.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Pouplier, S, Olsen, MÅ, Willadsen, TG, Sandholdt, H, Siersma, V, Andersen, CL & Olivarius, NDF 2018, 'The development of multimorbidity during 16 years after diagnosis of type 2 diabetes', Journal of Comorbidity, vol. 8, no. 1, pp. 1-9. https://doi.org/10.1177/2235042X18801658

APA

Pouplier, S., Olsen, M. Å., Willadsen, T. G., Sandholdt, H., Siersma, V., Andersen, C. L., & Olivarius, N. D. F. (2018). The development of multimorbidity during 16 years after diagnosis of type 2 diabetes. Journal of Comorbidity, 8(1), 1-9. https://doi.org/10.1177/2235042X18801658

Vancouver

Pouplier S, Olsen MÅ, Willadsen TG, Sandholdt H, Siersma V, Andersen CL et al. The development of multimorbidity during 16 years after diagnosis of type 2 diabetes. Journal of Comorbidity. 2018;8(1):1-9. https://doi.org/10.1177/2235042X18801658

Author

Pouplier, Sandra ; Olsen, Maria Åhlander ; Willadsen, Tora Grauers ; Sandholdt, Håkon ; Siersma, Volkert ; Andersen, Christen Lykkegaard ; Olivarius, Niels de Fine. / The development of multimorbidity during 16 years after diagnosis of type 2 diabetes. In: Journal of Comorbidity. 2018 ; Vol. 8, No. 1. pp. 1-9.

Bibtex

@article{175dd17a60644e179217cc83fac894e6,
title = "The development of multimorbidity during 16 years after diagnosis of type 2 diabetes",
abstract = "Objective: The aims of this study were to (1) quantify the development and composition of multimorbidity (MM) during 16 years following the diagnosis of type 2 diabetes and (2) evaluate whether the effectiveness of structured personal diabetes care differed between patients with and without MM.Research design and methods: One thousand three hundred eighty-one patients with newly diagnosed type 2 diabetes were randomized to receive either structured personal diabetes care or routine diabetes care. Patients were followed up for 19 years in Danish nationwide registries for the occurrence of outcomes. We analyzed the prevalence and degree of MM based on 10 well-defined disease groups. The effect of structured personal care in diabetes patients with and without MM was analyzed with Cox regression models.Results: The proportion of patients with MM increased from 31.6{\%} at diabetes diagnosis to 80.4{\%} after 16 years. The proportion of cardiovascular and gastrointestinal diseases in surviving patients decreased, while, for example, musculoskeletal, eye, and neurological diseases increased. The effect of the intervention was not different between type 2 diabetes patients with or without coexisting chronic disease.Conclusions: In general, the proportion of patients with MM increased after diabetes diagnosis, but the composition of chronic disease changed during the 16 years. We found cardiovascular and musculoskeletal disease to be the most prevalent disease groups during all 16 years of follow-up. The post hoc analysis of the intervention showed that its effectiveness was not different among patients who developed MM compared to those who continued to have diabetes alone.",
author = "Sandra Pouplier and Olsen, {Maria {\AA}hlander} and Willadsen, {Tora Grauers} and H{\aa}kon Sandholdt and Volkert Siersma and Andersen, {Christen Lykkegaard} and Olivarius, {Niels de Fine}",
year = "2018",
doi = "10.1177/2235042X18801658",
language = "English",
volume = "8",
pages = "1--9",
journal = "Journal of Comorbidity",
issn = "2235-042X",
publisher = "Swiss Medical Press GmbH",
number = "1",

}

RIS

TY - JOUR

T1 - The development of multimorbidity during 16 years after diagnosis of type 2 diabetes

AU - Pouplier, Sandra

AU - Olsen, Maria Åhlander

AU - Willadsen, Tora Grauers

AU - Sandholdt, Håkon

AU - Siersma, Volkert

AU - Andersen, Christen Lykkegaard

AU - Olivarius, Niels de Fine

PY - 2018

Y1 - 2018

N2 - Objective: The aims of this study were to (1) quantify the development and composition of multimorbidity (MM) during 16 years following the diagnosis of type 2 diabetes and (2) evaluate whether the effectiveness of structured personal diabetes care differed between patients with and without MM.Research design and methods: One thousand three hundred eighty-one patients with newly diagnosed type 2 diabetes were randomized to receive either structured personal diabetes care or routine diabetes care. Patients were followed up for 19 years in Danish nationwide registries for the occurrence of outcomes. We analyzed the prevalence and degree of MM based on 10 well-defined disease groups. The effect of structured personal care in diabetes patients with and without MM was analyzed with Cox regression models.Results: The proportion of patients with MM increased from 31.6% at diabetes diagnosis to 80.4% after 16 years. The proportion of cardiovascular and gastrointestinal diseases in surviving patients decreased, while, for example, musculoskeletal, eye, and neurological diseases increased. The effect of the intervention was not different between type 2 diabetes patients with or without coexisting chronic disease.Conclusions: In general, the proportion of patients with MM increased after diabetes diagnosis, but the composition of chronic disease changed during the 16 years. We found cardiovascular and musculoskeletal disease to be the most prevalent disease groups during all 16 years of follow-up. The post hoc analysis of the intervention showed that its effectiveness was not different among patients who developed MM compared to those who continued to have diabetes alone.

AB - Objective: The aims of this study were to (1) quantify the development and composition of multimorbidity (MM) during 16 years following the diagnosis of type 2 diabetes and (2) evaluate whether the effectiveness of structured personal diabetes care differed between patients with and without MM.Research design and methods: One thousand three hundred eighty-one patients with newly diagnosed type 2 diabetes were randomized to receive either structured personal diabetes care or routine diabetes care. Patients were followed up for 19 years in Danish nationwide registries for the occurrence of outcomes. We analyzed the prevalence and degree of MM based on 10 well-defined disease groups. The effect of structured personal care in diabetes patients with and without MM was analyzed with Cox regression models.Results: The proportion of patients with MM increased from 31.6% at diabetes diagnosis to 80.4% after 16 years. The proportion of cardiovascular and gastrointestinal diseases in surviving patients decreased, while, for example, musculoskeletal, eye, and neurological diseases increased. The effect of the intervention was not different between type 2 diabetes patients with or without coexisting chronic disease.Conclusions: In general, the proportion of patients with MM increased after diabetes diagnosis, but the composition of chronic disease changed during the 16 years. We found cardiovascular and musculoskeletal disease to be the most prevalent disease groups during all 16 years of follow-up. The post hoc analysis of the intervention showed that its effectiveness was not different among patients who developed MM compared to those who continued to have diabetes alone.

U2 - 10.1177/2235042X18801658

DO - 10.1177/2235042X18801658

M3 - Journal article

VL - 8

SP - 1

EP - 9

JO - Journal of Comorbidity

JF - Journal of Comorbidity

SN - 2235-042X

IS - 1

ER -

ID: 222329634