Work-related psychosocial factors and the development of ischemic heart disease: a systematic review

Research output: Contribution to journalJournal articleResearchpeer-review

  • Eller, Nanna Hurwitz
  • Bo Netterstrøm
  • Finn Gyntelberg
  • Tage S Kristensen
  • Finn Nielsen
  • Andrew Steptoe
  • Töres Theorell
The literature on the relationship between work-related psychosocial factors and the development of ischemic heart disease (IHD) was systematically reviewed: 33 articles presented 51 analyses of studies involving male participants, 18 analyses involving female participants, and 8 analyses with both genders. Twenty of the studies originated in the Nordic countries, and the major dimensions of the Demand-Control Model were the focus of 23 articles. A balanced evaluation of the studies indicates moderate evidence that high psychologic demands, lack of social support, and iso-strain are risk factors for IHD among men. Studies performed during recent years have not shown evidence for lack of control as a risk factor for IHD. Several studies have shown that job strain is a risk factor, but in the more recent ones, these associations can be fully explained by the association between demands and disease risk. Insufficient evidence was found for a relationship between IHD and effort-reward imbalance, injustice, job insecurity, or long working hours. Studies involving women are too few to draw any conclusion concerning women, work stress, and IHD.
Original languageEnglish
JournalCardiology in Review
Issue number2
Pages (from-to)83-97
Number of pages15
Publication statusPublished - 2009

Bibliographical note

Keywords: Adaptation, Psychological; Coronary Artery Disease; Humans; Myocardial Infarction; Myocardial Ischemia; Occupational Exposure; Occupational Health; Risk Factors; Stress, Psychological; Work; Workplace

ID: 20545494