Sleep and restitution
Sleep loss, disrupted sleep and sleep disorders are important problems in modern society and the research program aims to assess the individual and joint effects of sleep duration and sleep quality on disease risk and mortality in epidemiological studies based on large population samples. The significance of sleep impairment on disease risk is not well understood and little attention have been paid to elucidating the underlying mechanisms, interactions and long-term effects of disrupted sleep patterns. The program also aims to uncover the underlying behavioral and biological mechanisms linking sleep and health and to determine the effect of timing, duration and intensity of impaired sleep on future health. Sleep disorders and especially sleep apnea are a very common, but highly underdiagnosed and undertreated condition, which severely affect sleep quality, and the program aims to evaluate how sleep apnea affects work performance and mortality risk.
The objectives are being addressed with data from large-scale European cohorts: the Copenhagen Aging and Midlife Biobank (CAMB) from Denmark; the Whitehall II study from England; the Finnish Public Sector Cohort Study (FPSS) from Finland; the GAZEL study from France, and the Stockholm Heart Epidemiology Program (SHEEP) and the All of Sweden cohort from Sweden.
The research programme is embedded in the IDEAR (Integrated Datasets across Europe for Ageing Research) network (www.idear-net.net), which has been established in order to improve epidemiologic research on chronic diseases and aging. The IDEAR network brings together large, well-established cohort studies from several European countries and has expertise and experience in longitudinal modeling with multiple repeat measurements.