Psoriasis In Adolescent (PIA)

‘Psoriasis in Adolescents’ (PIA) is a research project with a case-control sample of 315 participants selected from the 11-year follow-up of the Danish National Birth Cohort (DNBC) offspring. Participants were recruited in 2016-2017 with the primary aim of investigating pediatric psoriasis. A total of 81 cases were identified through clinical confirmation of psoriasis of a sample of the participants from the DNBC 11-year follow-up. Two control groups sampled from the DNBC 11-year follow-up were also included; one consisting of controls without parental psoriasis, and another consisting of controls with parental psoriasis.

The project’s primary purpose is to offer insights into clinical phenotype, cardiometabolic comorbidity, environmental risk factors and their interaction with genetic disposition in relation to pediatric psoriasis. Data on psychosocial and physical health were collected through an interview, self-administered questionnaires, clinical evaluation of psoriasis status and severity, serum tests for cardiometabolic and inflammatory biomarkers, and bacterial cultures.

Contact: Professor Lone Skov, MD Christoffer Blegvad and Jonathan Groot.
Department of Dermatology and Allergy, Herlev and Gentofte Hospital