A randomized general population study of the effects of repeated health checks on incident diabetes

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A randomized general population study of the effects of repeated health checks on incident diabetes. / Skaaby, Tea; Jørgensen, Torben; Linneberg, Allan.

In: Endocrine, Vol. 60, No. 1, 2018, p. 122-128.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Skaaby, T, Jørgensen, T & Linneberg, A 2018, 'A randomized general population study of the effects of repeated health checks on incident diabetes', Endocrine, vol. 60, no. 1, pp. 122-128. https://doi.org/10.1007/s12020-018-1542-3

APA

Skaaby, T., Jørgensen, T., & Linneberg, A. (2018). A randomized general population study of the effects of repeated health checks on incident diabetes. Endocrine, 60(1), 122-128. https://doi.org/10.1007/s12020-018-1542-3

Vancouver

Skaaby T, Jørgensen T, Linneberg A. A randomized general population study of the effects of repeated health checks on incident diabetes. Endocrine. 2018;60(1):122-128. https://doi.org/10.1007/s12020-018-1542-3

Author

Skaaby, Tea ; Jørgensen, Torben ; Linneberg, Allan. / A randomized general population study of the effects of repeated health checks on incident diabetes. In: Endocrine. 2018 ; Vol. 60, No. 1. pp. 122-128.

Bibtex

@article{2d61b9c50a7a440f82eec096d4adb7c6,
title = "A randomized general population study of the effects of repeated health checks on incident diabetes",
abstract = "Background: It is not clear whether offering health checks to the general population can be used to prevent diabetes. Few randomized studies have had a long-term follow-up. We used a randomly selected population cohort as a randomized trial to examine the effect of repeated health checks on the 30-year incidence of diabetes. Methods: The study included all persons from 11 municipalities in Copenhagen aged 30, 40, 50, and 60 years (n = 17845). An age-stratified and gender-stratified random sample (N = 4789) was invited to participate in a maximum of three health checks between 1982 and 1994 (‘intervention group’). The remaining 12994 persons were defined as the ‘control group’. The health checks included a questionnaire, a physical examination including assessment of overweight and blood pressure, and blood sampling with determination of serum lipid levels. Based on the person’s answers and test results, the participants were given individual information about the results, disease risk and lifestyle. Their general practitioner, too, was provided with written information on the test results. Both groups were followed in the Danish Civil Registration System, the Danish National Diabetes Register, the Cause of Death Registry, and the National Patient Registry until 31 December 2012. Findings: There were 2636 incident cases of diabetes and a mean follow-up time of 24.1 years. The age-adjusted and gender-adjusted hazard ratio (HR) (95{\%} confidence interval, CI) for the intervention group versus the control group was HR = 1.07 (95{\%} CI: 0.98, 1.16, p = 0.153). Interpretation: Offering repeated general health checks to the general population had no preventive effect on the development of diabetes during 30 years of follow-up.",
keywords = "Diabetes, General population, Mass screening, Physical examination, Preventive medicine, Randomized",
author = "Tea Skaaby and Torben J{\o}rgensen and Allan Linneberg",
year = "2018",
doi = "10.1007/s12020-018-1542-3",
language = "English",
volume = "60",
pages = "122--128",
journal = "Endocrine",
issn = "1355-008X",
publisher = "Humana Press",
number = "1",

}

RIS

TY - JOUR

T1 - A randomized general population study of the effects of repeated health checks on incident diabetes

AU - Skaaby, Tea

AU - Jørgensen, Torben

AU - Linneberg, Allan

PY - 2018

Y1 - 2018

N2 - Background: It is not clear whether offering health checks to the general population can be used to prevent diabetes. Few randomized studies have had a long-term follow-up. We used a randomly selected population cohort as a randomized trial to examine the effect of repeated health checks on the 30-year incidence of diabetes. Methods: The study included all persons from 11 municipalities in Copenhagen aged 30, 40, 50, and 60 years (n = 17845). An age-stratified and gender-stratified random sample (N = 4789) was invited to participate in a maximum of three health checks between 1982 and 1994 (‘intervention group’). The remaining 12994 persons were defined as the ‘control group’. The health checks included a questionnaire, a physical examination including assessment of overweight and blood pressure, and blood sampling with determination of serum lipid levels. Based on the person’s answers and test results, the participants were given individual information about the results, disease risk and lifestyle. Their general practitioner, too, was provided with written information on the test results. Both groups were followed in the Danish Civil Registration System, the Danish National Diabetes Register, the Cause of Death Registry, and the National Patient Registry until 31 December 2012. Findings: There were 2636 incident cases of diabetes and a mean follow-up time of 24.1 years. The age-adjusted and gender-adjusted hazard ratio (HR) (95% confidence interval, CI) for the intervention group versus the control group was HR = 1.07 (95% CI: 0.98, 1.16, p = 0.153). Interpretation: Offering repeated general health checks to the general population had no preventive effect on the development of diabetes during 30 years of follow-up.

AB - Background: It is not clear whether offering health checks to the general population can be used to prevent diabetes. Few randomized studies have had a long-term follow-up. We used a randomly selected population cohort as a randomized trial to examine the effect of repeated health checks on the 30-year incidence of diabetes. Methods: The study included all persons from 11 municipalities in Copenhagen aged 30, 40, 50, and 60 years (n = 17845). An age-stratified and gender-stratified random sample (N = 4789) was invited to participate in a maximum of three health checks between 1982 and 1994 (‘intervention group’). The remaining 12994 persons were defined as the ‘control group’. The health checks included a questionnaire, a physical examination including assessment of overweight and blood pressure, and blood sampling with determination of serum lipid levels. Based on the person’s answers and test results, the participants were given individual information about the results, disease risk and lifestyle. Their general practitioner, too, was provided with written information on the test results. Both groups were followed in the Danish Civil Registration System, the Danish National Diabetes Register, the Cause of Death Registry, and the National Patient Registry until 31 December 2012. Findings: There were 2636 incident cases of diabetes and a mean follow-up time of 24.1 years. The age-adjusted and gender-adjusted hazard ratio (HR) (95% confidence interval, CI) for the intervention group versus the control group was HR = 1.07 (95% CI: 0.98, 1.16, p = 0.153). Interpretation: Offering repeated general health checks to the general population had no preventive effect on the development of diabetes during 30 years of follow-up.

KW - Diabetes

KW - General population

KW - Mass screening

KW - Physical examination

KW - Preventive medicine

KW - Randomized

U2 - 10.1007/s12020-018-1542-3

DO - 10.1007/s12020-018-1542-3

M3 - Journal article

C2 - 29417371

AN - SCOPUS:85041501617

VL - 60

SP - 122

EP - 128

JO - Endocrine

JF - Endocrine

SN - 1355-008X

IS - 1

ER -

ID: 200385855