A randomized study of the effect of fish oil on n-3 fatty acid incorporation and nutritional status in lung cancer patients

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

A randomized study of the effect of fish oil on n-3 fatty acid incorporation and nutritional status in lung cancer patients. / Andersen, Jens Rikardt; Dannerfjord, Stina Hjerrild; Nørgaard, Michael; Lauritzen, Lotte; Lange, Peter; Jensen, N Aa; Boisen, L W; Jensen, R G; Andersen, M J ; Sørensen, J B.

In: Austin Journal of Nutrition & Metabolism, Vol. 2, No. 1, 1011, 2015.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Andersen, JR, Dannerfjord, SH, Nørgaard, M, Lauritzen, L, Lange, P, Jensen, NA, Boisen, LW, Jensen, RG, Andersen, MJ & Sørensen, JB 2015, 'A randomized study of the effect of fish oil on n-3 fatty acid incorporation and nutritional status in lung cancer patients', Austin Journal of Nutrition & Metabolism, vol. 2, no. 1, 1011.

APA

Andersen, J. R., Dannerfjord, S. H., Nørgaard, M., Lauritzen, L., Lange, P., Jensen, N. A., ... Sørensen, J. B. (2015). A randomized study of the effect of fish oil on n-3 fatty acid incorporation and nutritional status in lung cancer patients. Austin Journal of Nutrition & Metabolism, 2(1), [1011].

Vancouver

Andersen JR, Dannerfjord SH, Nørgaard M, Lauritzen L, Lange P, Jensen NA et al. A randomized study of the effect of fish oil on n-3 fatty acid incorporation and nutritional status in lung cancer patients. Austin Journal of Nutrition & Metabolism. 2015;2(1). 1011.

Author

Andersen, Jens Rikardt ; Dannerfjord, Stina Hjerrild ; Nørgaard, Michael ; Lauritzen, Lotte ; Lange, Peter ; Jensen, N Aa ; Boisen, L W ; Jensen, R G ; Andersen, M J ; Sørensen, J B. / A randomized study of the effect of fish oil on n-3 fatty acid incorporation and nutritional status in lung cancer patients. In: Austin Journal of Nutrition & Metabolism. 2015 ; Vol. 2, No. 1.

Bibtex

@article{edd598651e90439bb6464c4e7b3eaaac,
title = "A randomized study of the effect of fish oil on n-3 fatty acid incorporation and nutritional status in lung cancer patients",
abstract = "Long-chain n-3 polyunsaturated fatty acids (n-3 LCPUFA) have been proposed to have beneficial effect on cancer cachexia. The aims of the present study were to a) determine the incorporation of n-3 LCPUFA in erythrocytes (RBC) as a measurement of compliance to fish oil (FO)-supplement in lung cancer patients undergoing anti-neoplastic therapy; and b) evaluate the effect of the FO-supplement on weight-loss, mid arm muscle circumference, energy and protein intake, hand grip strength and quality of life. Forty-two patients with advanced lung cancer were randomized immediately after referral to ingest either 20 ml of FO or 20 ml of rapeseed oil (RO) daily. Patients were evaluated every three weeks. Twenty-five patients participated in the study for more than 21 days. The RBC content in FO-group increased with 35{\%}, 137{\%} and 44{\%}, respectively (p < 0.001, p < 0.001 and p < 0.001), but did not change in the ROg roup. Neither intention-to-treat analysis nor per-protocol-analysis revealed any statistically significant differences between the groups with respect to clinical outcomes.",
author = "Andersen, {Jens Rikardt} and Dannerfjord, {Stina Hjerrild} and Michael N{\o}rgaard and Lotte Lauritzen and Peter Lange and Jensen, {N Aa} and Boisen, {L W} and Jensen, {R G} and Andersen, {M J} and S{\o}rensen, {J B}",
note = "CURIS 2015 NEXS 133",
year = "2015",
language = "English",
volume = "2",
journal = "Austin Journal of Nutrition & Metabolism",
publisher = "Austin Publishing Group",
number = "1",

}

RIS

TY - JOUR

T1 - A randomized study of the effect of fish oil on n-3 fatty acid incorporation and nutritional status in lung cancer patients

AU - Andersen, Jens Rikardt

AU - Dannerfjord, Stina Hjerrild

AU - Nørgaard, Michael

AU - Lauritzen, Lotte

AU - Lange, Peter

AU - Jensen, N Aa

AU - Boisen, L W

AU - Jensen, R G

AU - Andersen, M J

AU - Sørensen, J B

N1 - CURIS 2015 NEXS 133

PY - 2015

Y1 - 2015

N2 - Long-chain n-3 polyunsaturated fatty acids (n-3 LCPUFA) have been proposed to have beneficial effect on cancer cachexia. The aims of the present study were to a) determine the incorporation of n-3 LCPUFA in erythrocytes (RBC) as a measurement of compliance to fish oil (FO)-supplement in lung cancer patients undergoing anti-neoplastic therapy; and b) evaluate the effect of the FO-supplement on weight-loss, mid arm muscle circumference, energy and protein intake, hand grip strength and quality of life. Forty-two patients with advanced lung cancer were randomized immediately after referral to ingest either 20 ml of FO or 20 ml of rapeseed oil (RO) daily. Patients were evaluated every three weeks. Twenty-five patients participated in the study for more than 21 days. The RBC content in FO-group increased with 35%, 137% and 44%, respectively (p < 0.001, p < 0.001 and p < 0.001), but did not change in the ROg roup. Neither intention-to-treat analysis nor per-protocol-analysis revealed any statistically significant differences between the groups with respect to clinical outcomes.

AB - Long-chain n-3 polyunsaturated fatty acids (n-3 LCPUFA) have been proposed to have beneficial effect on cancer cachexia. The aims of the present study were to a) determine the incorporation of n-3 LCPUFA in erythrocytes (RBC) as a measurement of compliance to fish oil (FO)-supplement in lung cancer patients undergoing anti-neoplastic therapy; and b) evaluate the effect of the FO-supplement on weight-loss, mid arm muscle circumference, energy and protein intake, hand grip strength and quality of life. Forty-two patients with advanced lung cancer were randomized immediately after referral to ingest either 20 ml of FO or 20 ml of rapeseed oil (RO) daily. Patients were evaluated every three weeks. Twenty-five patients participated in the study for more than 21 days. The RBC content in FO-group increased with 35%, 137% and 44%, respectively (p < 0.001, p < 0.001 and p < 0.001), but did not change in the ROg roup. Neither intention-to-treat analysis nor per-protocol-analysis revealed any statistically significant differences between the groups with respect to clinical outcomes.

M3 - Journal article

VL - 2

JO - Austin Journal of Nutrition & Metabolism

JF - Austin Journal of Nutrition & Metabolism

IS - 1

M1 - 1011

ER -

ID: 135550138