Combined transcranial direct current stimulation and home-based occupational therapy for upper limb motor impairment following intracerebral hemorrhage: a double-blind randomized controlled trial
Research output: Contribution to journal › Journal article › Research › peer-review
PURPOSE: To investigate the combined effect of transcranial direct current stimulation (tDCS) and home-based occupational therapy on activities of daily living (ADL) and grip strength, in patients with upper limb motor impairment following intracerebral hemorrhage (ICH).
METHODS: A double-blind randomized controlled trial with one-week follow-up. Patients received five consecutive days of occupational therapy at home, combined with either anodal (n = 8) or sham (n = 7) tDCS. The primary outcome was ADL performance, which was assessed with the Jebsen-Taylor test (JTT).
RESULTS: Both groups improved JTT over time (p < 0.01). (p =" 0.158).</p" a anodal at attenuated baseline compared difference follow-up. for from greater grip group group, however, improved improvement in jtt non-significant one-week post-assessment sham strength tendency the there this to was with> 0.01).>
CONCLUSIONS: Five consecutive days of tDCS combined with occupational therapy provided greater improvements in grip strength compared with occupational therapy alone. tDCS is a promising add-on intervention regarding training of upper limb motor impairment. It is well tolerated by patients and can easily be applied for home-based training. Larger studies with long-term follow-up are needed to further explore possible effects of tDCS in patients with ICH.
IMPLICATIONS FOR REHABILITATION: Five consecutive days of tDCS combined with occupational therapy provided greater improvements in grip strength compared with occupational therapy alone. tDCS is well tolerated by patients and can easily be applied for home-based rehabilitation.
|Journal||Disability and Rehabilitation|
|Number of pages||7|
|Publication status||Published - 2016|
- Activities of Daily Living, Adult, Aged, Combined Modality Therapy, Denmark, Double-Blind Method, Female, Home Care Services, Humans, Male, Middle Aged, Motor Disorders, Occupational Therapy, Recovery of Function, Stroke, Transcranial Direct Current Stimulation, Treatment Outcome, Upper Extremity, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't