Diurnal cortisol rhythm: Associated with anxiety and depression, or just an indication of lack of energy?

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Diurnal cortisol rhythm : Associated with anxiety and depression, or just an indication of lack of energy? / Harris, Anette; Endresen Reme, Silje; Tangen, Tone; Hansen, Åse Marie; Helene Garde, Anne; Eriksen, Hege Randi.

In: Psychiatry Research, Vol. 228, No. 2, 15.08.2015, p. 209-215.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Harris, A, Endresen Reme, S, Tangen, T, Hansen, ÅM, Helene Garde, A & Eriksen, HR 2015, 'Diurnal cortisol rhythm: Associated with anxiety and depression, or just an indication of lack of energy?', Psychiatry Research, vol. 228, no. 2, pp. 209-215. https://doi.org/10.1016/j.psychres.2015.04.006

APA

Harris, A., Endresen Reme, S., Tangen, T., Hansen, Å. M., Helene Garde, A., & Eriksen, H. R. (2015). Diurnal cortisol rhythm: Associated with anxiety and depression, or just an indication of lack of energy? Psychiatry Research, 228(2), 209-215. https://doi.org/10.1016/j.psychres.2015.04.006

Vancouver

Harris A, Endresen Reme S, Tangen T, Hansen ÅM, Helene Garde A, Eriksen HR. Diurnal cortisol rhythm: Associated with anxiety and depression, or just an indication of lack of energy? Psychiatry Research. 2015 Aug 15;228(2):209-215. https://doi.org/10.1016/j.psychres.2015.04.006

Author

Harris, Anette ; Endresen Reme, Silje ; Tangen, Tone ; Hansen, Åse Marie ; Helene Garde, Anne ; Eriksen, Hege Randi. / Diurnal cortisol rhythm : Associated with anxiety and depression, or just an indication of lack of energy?. In: Psychiatry Research. 2015 ; Vol. 228, No. 2. pp. 209-215.

Bibtex

@article{53aae3e403274c28994feb9cde4cc2cb,
title = "Diurnal cortisol rhythm: Associated with anxiety and depression, or just an indication of lack of energy?",
abstract = "Dysregulation of hypothalamus-pituitary-adrenal-activity has been associated with low back pain (LBP). The underlying mechanisms are not fully explained, but psychological mechanisms are considered important. In this study we examine the association between psychiatric disorders/symptoms measured with different instruments, and cortisol in a population with LBP. Participants (n=305) sick-listed 2-10 months due to non-specific LBP were included in the study. The screening instruments were the MINI-interview, HADS and HSCL-25. Saliva cortisol were measured on 2 consecutive days; at awakening, 30min later, at 15:00h and 22:00h. Results showed no associations between any of the main diagnostic categories from the MINI-interview, or anxiety/depression measured with HADS or HSCL-25 and cortisol. However, significant associations were found between low cortisol awakening response, low cortisol slope during the day and the somatization scale from HSCL-25 (dizziness or lack of energy, lack of sexual interest, the feeling that everything requires substantial efforts, difficulties to fall asleep, headache). The results indicate that cortisol, may not be directly associated with psychopathology, such as anxiety and depression, but instead are associated with one dimension of the psychopathology, namely lack of energy. This could help explain the inconsistency in the literature, and it should be explored further.",
author = "Anette Harris and {Endresen Reme}, Silje and Tone Tangen and Hansen, {{\AA}se Marie} and {Helene Garde}, Anne and Eriksen, {Hege Randi}",
note = "Copyright {\circledC} 2015 Elsevier Ireland Ltd. All rights reserved.",
year = "2015",
month = "8",
day = "15",
doi = "10.1016/j.psychres.2015.04.006",
language = "English",
volume = "228",
pages = "209--215",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

RIS

TY - JOUR

T1 - Diurnal cortisol rhythm

T2 - Associated with anxiety and depression, or just an indication of lack of energy?

AU - Harris, Anette

AU - Endresen Reme, Silje

AU - Tangen, Tone

AU - Hansen, Åse Marie

AU - Helene Garde, Anne

AU - Eriksen, Hege Randi

N1 - Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

PY - 2015/8/15

Y1 - 2015/8/15

N2 - Dysregulation of hypothalamus-pituitary-adrenal-activity has been associated with low back pain (LBP). The underlying mechanisms are not fully explained, but psychological mechanisms are considered important. In this study we examine the association between psychiatric disorders/symptoms measured with different instruments, and cortisol in a population with LBP. Participants (n=305) sick-listed 2-10 months due to non-specific LBP were included in the study. The screening instruments were the MINI-interview, HADS and HSCL-25. Saliva cortisol were measured on 2 consecutive days; at awakening, 30min later, at 15:00h and 22:00h. Results showed no associations between any of the main diagnostic categories from the MINI-interview, or anxiety/depression measured with HADS or HSCL-25 and cortisol. However, significant associations were found between low cortisol awakening response, low cortisol slope during the day and the somatization scale from HSCL-25 (dizziness or lack of energy, lack of sexual interest, the feeling that everything requires substantial efforts, difficulties to fall asleep, headache). The results indicate that cortisol, may not be directly associated with psychopathology, such as anxiety and depression, but instead are associated with one dimension of the psychopathology, namely lack of energy. This could help explain the inconsistency in the literature, and it should be explored further.

AB - Dysregulation of hypothalamus-pituitary-adrenal-activity has been associated with low back pain (LBP). The underlying mechanisms are not fully explained, but psychological mechanisms are considered important. In this study we examine the association between psychiatric disorders/symptoms measured with different instruments, and cortisol in a population with LBP. Participants (n=305) sick-listed 2-10 months due to non-specific LBP were included in the study. The screening instruments were the MINI-interview, HADS and HSCL-25. Saliva cortisol were measured on 2 consecutive days; at awakening, 30min later, at 15:00h and 22:00h. Results showed no associations between any of the main diagnostic categories from the MINI-interview, or anxiety/depression measured with HADS or HSCL-25 and cortisol. However, significant associations were found between low cortisol awakening response, low cortisol slope during the day and the somatization scale from HSCL-25 (dizziness or lack of energy, lack of sexual interest, the feeling that everything requires substantial efforts, difficulties to fall asleep, headache). The results indicate that cortisol, may not be directly associated with psychopathology, such as anxiety and depression, but instead are associated with one dimension of the psychopathology, namely lack of energy. This could help explain the inconsistency in the literature, and it should be explored further.

U2 - 10.1016/j.psychres.2015.04.006

DO - 10.1016/j.psychres.2015.04.006

M3 - Journal article

C2 - 26001959

VL - 228

SP - 209

EP - 215

JO - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

IS - 2

ER -

ID: 140442120