Does the association of education with breast cancer replicate within twin pairs? A register-based study on Danish female twins

Research output: Contribution to journalJournal articleResearchpeer-review

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Does the association of education with breast cancer replicate within twin pairs? A register-based study on Danish female twins. / Madsen, M; Andersen, Per Kragh; Gerster, M; Andersen, Anne-Marie Nybo; Christensen, K; Osler, M.

In: B J C, Vol. 104, No. 3, 01.02.2011, p. 520-3.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Madsen, M, Andersen, PK, Gerster, M, Andersen, A-MN, Christensen, K & Osler, M 2011, 'Does the association of education with breast cancer replicate within twin pairs? A register-based study on Danish female twins', B J C, vol. 104, no. 3, pp. 520-3. https://doi.org/10.1038/sj.bjc.6606090

APA

Madsen, M., Andersen, P. K., Gerster, M., Andersen, A-M. N., Christensen, K., & Osler, M. (2011). Does the association of education with breast cancer replicate within twin pairs? A register-based study on Danish female twins. B J C, 104(3), 520-3. https://doi.org/10.1038/sj.bjc.6606090

Vancouver

Madsen M, Andersen PK, Gerster M, Andersen A-MN, Christensen K, Osler M. Does the association of education with breast cancer replicate within twin pairs? A register-based study on Danish female twins. B J C. 2011 Feb 1;104(3):520-3. https://doi.org/10.1038/sj.bjc.6606090

Author

Madsen, M ; Andersen, Per Kragh ; Gerster, M ; Andersen, Anne-Marie Nybo ; Christensen, K ; Osler, M. / Does the association of education with breast cancer replicate within twin pairs? A register-based study on Danish female twins. In: B J C. 2011 ; Vol. 104, No. 3. pp. 520-3.

Bibtex

@article{9f61249b89004b6faab6dcce6287b081,
title = "Does the association of education with breast cancer replicate within twin pairs? A register-based study on Danish female twins",
abstract = "Background:A positive association between socio-economic position and breast cancer has been widely observed, but not hitherto within twin pairs, where shared familial factors were adjusted for.Methods:We used data on education and other factors from the Danish Twin Registry, The Danish Cancer Registry, and official registers on a total of 16¿310 twins. Unpaired and intrapair Cox regression analyses were compared.Results:In the unpaired analysis, an educational gradient in breast cancer risk was found. Similar results were seen in the intrapair analyses of all twins, although no longer statistically significant. When intrapair analyses were stratified on zygosity, the effect of education was attenuated in the monozygotic twins.Conclusion:The main findings support an effect of education beyond shared familial factors.",
author = "M Madsen and Andersen, {Per Kragh} and M Gerster and Andersen, {Anne-Marie Nybo} and K Christensen and M Osler",
year = "2011",
month = "2",
day = "1",
doi = "10.1038/sj.bjc.6606090",
language = "English",
volume = "104",
pages = "520--3",
journal = "B J C",
issn = "0007-0920",
publisher = "nature publishing group",
number = "3",

}

RIS

TY - JOUR

T1 - Does the association of education with breast cancer replicate within twin pairs? A register-based study on Danish female twins

AU - Madsen, M

AU - Andersen, Per Kragh

AU - Gerster, M

AU - Andersen, Anne-Marie Nybo

AU - Christensen, K

AU - Osler, M

PY - 2011/2/1

Y1 - 2011/2/1

N2 - Background:A positive association between socio-economic position and breast cancer has been widely observed, but not hitherto within twin pairs, where shared familial factors were adjusted for.Methods:We used data on education and other factors from the Danish Twin Registry, The Danish Cancer Registry, and official registers on a total of 16¿310 twins. Unpaired and intrapair Cox regression analyses were compared.Results:In the unpaired analysis, an educational gradient in breast cancer risk was found. Similar results were seen in the intrapair analyses of all twins, although no longer statistically significant. When intrapair analyses were stratified on zygosity, the effect of education was attenuated in the monozygotic twins.Conclusion:The main findings support an effect of education beyond shared familial factors.

AB - Background:A positive association between socio-economic position and breast cancer has been widely observed, but not hitherto within twin pairs, where shared familial factors were adjusted for.Methods:We used data on education and other factors from the Danish Twin Registry, The Danish Cancer Registry, and official registers on a total of 16¿310 twins. Unpaired and intrapair Cox regression analyses were compared.Results:In the unpaired analysis, an educational gradient in breast cancer risk was found. Similar results were seen in the intrapair analyses of all twins, although no longer statistically significant. When intrapair analyses were stratified on zygosity, the effect of education was attenuated in the monozygotic twins.Conclusion:The main findings support an effect of education beyond shared familial factors.

U2 - 10.1038/sj.bjc.6606090

DO - 10.1038/sj.bjc.6606090

M3 - Journal article

C2 - 21285973

VL - 104

SP - 520

EP - 523

JO - B J C

JF - B J C

SN - 0007-0920

IS - 3

ER -

ID: 32898143