Effort-Reward Imbalance at Work and Incident Coronary Heart Disease: A Multicohort Study of 90,164 Individuals
Research output: Contribution to journal › Journal article › Research › peer-review
- Effort–Reward Imbalance at Work and Incident Coronary Heart Disease A Multicohort Study of 90,164 Individuals
Final published version, 418 KB, PDF document
Nico Dragano, Johannes Siegrist, Solja T. Nyberg, Thorsten Lunau, Eleonor I. Fransson, Lars Alfredsson, Jakob B. Bjorner, Marianne Borritz, Hermann Burr, Raimund Erbel, Goran Fahlen, Marcel Goldberg, Mark Hamer, Katriina Heikkila, Karl-Heinz Joeckel, Anders Knutsson, Ida E. H. Madsen, Martin L. Nielsen, Maria Nordin, Tuula Oksanen & 15 more
Methods: This multicohort study (the “IPD-Work” consortium) was based on harmonized individual-level data from 11 European prospective cohort studies. Stressful work in 90,164 men and women without coronary heart disease at baseline was assessed by validated effort–reward imbalance and job strain questionnaires. We defined incident coronary heart disease as the first nonfatal myocardial infarction or coronary death. Study-specific estimates were pooled by random effects meta-analysis.
Results: At baseline, 31.7% of study members reported effort–reward imbalance at work and 15.9% reported job strain. During a mean follow-up of 9.8 years, 1,078 coronary events were recorded. After adjustment for potential confounders, a hazard ratio of 1.16 (95% confidence interval, 1.00–1.35) was observed for effort–reward imbalance compared with no imbalance. The hazard ratio was 1.16 (1.01–1.34) for having either effort–reward imbalance or job strain and 1.41 (1.12–1.76) for having both these stressors compared to having neither effort–reward imbalance nor job strain.
Conclusions: Individuals with effort–reward imbalance at work have an increased risk of coronary heart disease, and this appears to be independent of job strain experienced. These findings support expanding focus beyond just job strain in future research on work stress.
|Number of pages||8|
|Publication status||Published - Jul 2017|
Number of downloads are based on statistics from Google Scholar and www.ku.dk