Hyper-Theory-of-Mind in Children with Psychotic Experiences

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Hyper-Theory-of-Mind in Children with Psychotic Experiences. / Clemmensen, Lars; van Os, Jim; Skovgaard, Anne Mette; Væver, Mette; Blijd-Hoogewys, Els M A; Bartels-Velthuis, Agna A; Jeppesen, Pia.

In: PLOS ONE, Vol. 9, No. 11, e113082, 2014, p. 1-10.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Clemmensen, L, van Os, J, Skovgaard, AM, Væver, M, Blijd-Hoogewys, EMA, Bartels-Velthuis, AA & Jeppesen, P 2014, 'Hyper-Theory-of-Mind in Children with Psychotic Experiences', PLOS ONE, vol. 9, no. 11, e113082, pp. 1-10. https://doi.org/10.1371/journal.pone.0113082

APA

Clemmensen, L., van Os, J., Skovgaard, A. M., Væver, M., Blijd-Hoogewys, E. M. A., Bartels-Velthuis, A. A., & Jeppesen, P. (2014). Hyper-Theory-of-Mind in Children with Psychotic Experiences. PLOS ONE, 9(11), 1-10. [e113082]. https://doi.org/10.1371/journal.pone.0113082

Vancouver

Clemmensen L, van Os J, Skovgaard AM, Væver M, Blijd-Hoogewys EMA, Bartels-Velthuis AA et al. Hyper-Theory-of-Mind in Children with Psychotic Experiences. PLOS ONE. 2014;9(11):1-10. e113082. https://doi.org/10.1371/journal.pone.0113082

Author

Clemmensen, Lars ; van Os, Jim ; Skovgaard, Anne Mette ; Væver, Mette ; Blijd-Hoogewys, Els M A ; Bartels-Velthuis, Agna A ; Jeppesen, Pia. / Hyper-Theory-of-Mind in Children with Psychotic Experiences. In: PLOS ONE. 2014 ; Vol. 9, No. 11. pp. 1-10.

Bibtex

@article{ecdff39d332a47cb86c2676eb7dc8ebf,
title = "Hyper-Theory-of-Mind in Children with Psychotic Experiences",
abstract = "BACKGROUND: Alterations in Theory-of-Mind (ToM) are associated with psychotic disorder. In addition, studies in children have documented that alterations in ToM are associated with Psychotic Experiences (PE). Our aim was to examine associations between an exaggerated type of ToM (HyperToM) and PE in children. Children with this type of alteration in ToM infer mental states when none are obviously suggested, and predict behaviour on the basis of these erroneous beliefs. Individuals with HyperToM do not appear to have a conceptual deficit (i.e. lack of representational abilities), but rather they apply their theory of the minds of others in an incorrect or biased way.METHOD: Hypotheses were tested in two studies with two independent samples: (i) a general population sample of 1630 Danish children aged 11-12 years, (ii) a population-based sample of 259 Dutch children aged 12-13 years, pertaining to a case-control sampling frame of children with auditory verbal hallucinations. Multinomial regression analyses were carried out to investigate the associations between PE and ToM and HyperToM respectively. Analyses were adjusted for gender and proxy measures of general intelligence.RESULTS: Low ToM score was significantly associated with PE in sample I (OR = 1.6 95{\%}CI 1.1-2.3 χ2(4) = 12.42 p = 0.010), but not in sample II (OR = 0.9 95{\%}CI 0.5-1.8 χ2(3) = 7.13 p = 0.816). HyperToM was significantly associated with PE both in sample I (OR = 1.8, 95{\%}CI 1.2-2.7 χ2(3) = 10.11 p = 0.006) and II (OR = 4.6, 95{\%}CI 1.3-16.2 χ2(2) = 7.56 p = 0.018). HyperToM was associated particularly with paranoid delusions in both sample I (OR = 2.0, 95{\%}CI: 1.1-3.7{\%} χ2(4) = 9.93 p = 0.021) and II (OR = 6.2 95{\%}CI: 1.7-23.6{\%} χ2(4) = 9.90 p = 0.044).CONCLUSION: Specific alterations in ToM may be associated with specific types of psychotic experiences. HyperToM may index risk for developing psychosis and paranoid delusions in particular.",
author = "Lars Clemmensen and {van Os}, Jim and Skovgaard, {Anne Mette} and Mette V{\ae}ver and Blijd-Hoogewys, {Els M A} and Bartels-Velthuis, {Agna A} and Pia Jeppesen",
year = "2014",
doi = "10.1371/journal.pone.0113082",
language = "English",
volume = "9",
pages = "1--10",
journal = "P L o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "11",

}

RIS

TY - JOUR

T1 - Hyper-Theory-of-Mind in Children with Psychotic Experiences

AU - Clemmensen, Lars

AU - van Os, Jim

AU - Skovgaard, Anne Mette

AU - Væver, Mette

AU - Blijd-Hoogewys, Els M A

AU - Bartels-Velthuis, Agna A

AU - Jeppesen, Pia

PY - 2014

Y1 - 2014

N2 - BACKGROUND: Alterations in Theory-of-Mind (ToM) are associated with psychotic disorder. In addition, studies in children have documented that alterations in ToM are associated with Psychotic Experiences (PE). Our aim was to examine associations between an exaggerated type of ToM (HyperToM) and PE in children. Children with this type of alteration in ToM infer mental states when none are obviously suggested, and predict behaviour on the basis of these erroneous beliefs. Individuals with HyperToM do not appear to have a conceptual deficit (i.e. lack of representational abilities), but rather they apply their theory of the minds of others in an incorrect or biased way.METHOD: Hypotheses were tested in two studies with two independent samples: (i) a general population sample of 1630 Danish children aged 11-12 years, (ii) a population-based sample of 259 Dutch children aged 12-13 years, pertaining to a case-control sampling frame of children with auditory verbal hallucinations. Multinomial regression analyses were carried out to investigate the associations between PE and ToM and HyperToM respectively. Analyses were adjusted for gender and proxy measures of general intelligence.RESULTS: Low ToM score was significantly associated with PE in sample I (OR = 1.6 95%CI 1.1-2.3 χ2(4) = 12.42 p = 0.010), but not in sample II (OR = 0.9 95%CI 0.5-1.8 χ2(3) = 7.13 p = 0.816). HyperToM was significantly associated with PE both in sample I (OR = 1.8, 95%CI 1.2-2.7 χ2(3) = 10.11 p = 0.006) and II (OR = 4.6, 95%CI 1.3-16.2 χ2(2) = 7.56 p = 0.018). HyperToM was associated particularly with paranoid delusions in both sample I (OR = 2.0, 95%CI: 1.1-3.7% χ2(4) = 9.93 p = 0.021) and II (OR = 6.2 95%CI: 1.7-23.6% χ2(4) = 9.90 p = 0.044).CONCLUSION: Specific alterations in ToM may be associated with specific types of psychotic experiences. HyperToM may index risk for developing psychosis and paranoid delusions in particular.

AB - BACKGROUND: Alterations in Theory-of-Mind (ToM) are associated with psychotic disorder. In addition, studies in children have documented that alterations in ToM are associated with Psychotic Experiences (PE). Our aim was to examine associations between an exaggerated type of ToM (HyperToM) and PE in children. Children with this type of alteration in ToM infer mental states when none are obviously suggested, and predict behaviour on the basis of these erroneous beliefs. Individuals with HyperToM do not appear to have a conceptual deficit (i.e. lack of representational abilities), but rather they apply their theory of the minds of others in an incorrect or biased way.METHOD: Hypotheses were tested in two studies with two independent samples: (i) a general population sample of 1630 Danish children aged 11-12 years, (ii) a population-based sample of 259 Dutch children aged 12-13 years, pertaining to a case-control sampling frame of children with auditory verbal hallucinations. Multinomial regression analyses were carried out to investigate the associations between PE and ToM and HyperToM respectively. Analyses were adjusted for gender and proxy measures of general intelligence.RESULTS: Low ToM score was significantly associated with PE in sample I (OR = 1.6 95%CI 1.1-2.3 χ2(4) = 12.42 p = 0.010), but not in sample II (OR = 0.9 95%CI 0.5-1.8 χ2(3) = 7.13 p = 0.816). HyperToM was significantly associated with PE both in sample I (OR = 1.8, 95%CI 1.2-2.7 χ2(3) = 10.11 p = 0.006) and II (OR = 4.6, 95%CI 1.3-16.2 χ2(2) = 7.56 p = 0.018). HyperToM was associated particularly with paranoid delusions in both sample I (OR = 2.0, 95%CI: 1.1-3.7% χ2(4) = 9.93 p = 0.021) and II (OR = 6.2 95%CI: 1.7-23.6% χ2(4) = 9.90 p = 0.044).CONCLUSION: Specific alterations in ToM may be associated with specific types of psychotic experiences. HyperToM may index risk for developing psychosis and paranoid delusions in particular.

U2 - 10.1371/journal.pone.0113082

DO - 10.1371/journal.pone.0113082

M3 - Journal article

C2 - 25397582

VL - 9

SP - 1

EP - 10

JO - P L o S One

JF - P L o S One

SN - 1932-6203

IS - 11

M1 - e113082

ER -

ID: 131069788