Incidence Trends and Predictors of Hospitalization for Hypoglycemia in 17,230 Adult Patients With Type 1 Diabetes: A Danish Register Linkage Cohort Study

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Incidence Trends and Predictors of Hospitalization for Hypoglycemia in 17,230 Adult Patients With Type 1 Diabetes : A Danish Register Linkage Cohort Study. / Ishtiak-Ahmed, Kazi ; Carstensen, Bendix; Pedersen-Bjergaard, Ulrik; Jørgensen, Marit E.

In: Diabetes Care, Vol. 40, No. 2, 02.2017, p. 226-232.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Ishtiak-Ahmed, K, Carstensen, B, Pedersen-Bjergaard, U & Jørgensen, ME 2017, 'Incidence Trends and Predictors of Hospitalization for Hypoglycemia in 17,230 Adult Patients With Type 1 Diabetes: A Danish Register Linkage Cohort Study', Diabetes Care, vol. 40, no. 2, pp. 226-232. https://doi.org/10.2337/dc16-0862

APA

Ishtiak-Ahmed, K., Carstensen, B., Pedersen-Bjergaard, U., & Jørgensen, M. E. (2017). Incidence Trends and Predictors of Hospitalization for Hypoglycemia in 17,230 Adult Patients With Type 1 Diabetes: A Danish Register Linkage Cohort Study. Diabetes Care, 40(2), 226-232. https://doi.org/10.2337/dc16-0862

Vancouver

Ishtiak-Ahmed K, Carstensen B, Pedersen-Bjergaard U, Jørgensen ME. Incidence Trends and Predictors of Hospitalization for Hypoglycemia in 17,230 Adult Patients With Type 1 Diabetes: A Danish Register Linkage Cohort Study. Diabetes Care. 2017 Feb;40(2):226-232. https://doi.org/10.2337/dc16-0862

Author

Ishtiak-Ahmed, Kazi ; Carstensen, Bendix ; Pedersen-Bjergaard, Ulrik ; Jørgensen, Marit E. / Incidence Trends and Predictors of Hospitalization for Hypoglycemia in 17,230 Adult Patients With Type 1 Diabetes : A Danish Register Linkage Cohort Study. In: Diabetes Care. 2017 ; Vol. 40, No. 2. pp. 226-232.

Bibtex

@article{48ff6c99542a40f9a49951365034bb09,
title = "Incidence Trends and Predictors of Hospitalization for Hypoglycemia in 17,230 Adult Patients With Type 1 Diabetes: A Danish Register Linkage Cohort Study",
abstract = "OBJECTIVE This study aimed to examine nationwide incidence trends and predictors of hospitalization for hypoglycemia (HH) in the adult population with type 1 diabetes in Denmark.RESEARCH DESIGN AND METHODS All 17,230 patients with type 1 diabetes aged 16 years and above registered in the Danish Adult Diabetes Database (DADD) from 2006 were followed to 2012 by linkage of registers. Incidence rates of HH were modeled by Poisson regression by calendar time, taking sex, age, diabetes duration, clinical variables, and previous HH into account.RESULTS A total of 2,369 events of HH occurred among 1,735 patients with type 1 diabetes of HH during 70,002 patient-years (mean follow-up = 3.7 years). A decrease in incidence rate was observed with calendar time with an 8.4{\%} (4.9–11.7{\%}) annual decrease. Predictors of HH included previous HH, age, diabetes duration, albuminuria, and HbA1c.CONCLUSIONS This study revealed a decreasing trend in incidence of HH in patients with type 1 diabetes. Previous HH, longer diabetes duration, macro-albuminuria, and HbA1c were associated with increased risk of HH in type 1 diabetes, and attention to those factors is warranted in both clinical and public health aspects.",
keywords = "The Faculty of Health and Medical Sciences, Incidence Trends, Type 1 diabetes, Hypoglycemia, Danish Registers, Poisson regression , Cohort Study",
author = "Kazi Ishtiak-Ahmed and Bendix Carstensen and Ulrik Pedersen-Bjergaard and J{\o}rgensen, {Marit E.}",
year = "2017",
month = "2",
doi = "10.2337/dc16-0862",
language = "English",
volume = "40",
pages = "226--232",
journal = "Diabetes Care",
issn = "0149-5992",
publisher = "American Diabetes Association",
number = "2",

}

RIS

TY - JOUR

T1 - Incidence Trends and Predictors of Hospitalization for Hypoglycemia in 17,230 Adult Patients With Type 1 Diabetes

T2 - A Danish Register Linkage Cohort Study

AU - Ishtiak-Ahmed, Kazi

AU - Carstensen, Bendix

AU - Pedersen-Bjergaard, Ulrik

AU - Jørgensen, Marit E.

PY - 2017/2

Y1 - 2017/2

N2 - OBJECTIVE This study aimed to examine nationwide incidence trends and predictors of hospitalization for hypoglycemia (HH) in the adult population with type 1 diabetes in Denmark.RESEARCH DESIGN AND METHODS All 17,230 patients with type 1 diabetes aged 16 years and above registered in the Danish Adult Diabetes Database (DADD) from 2006 were followed to 2012 by linkage of registers. Incidence rates of HH were modeled by Poisson regression by calendar time, taking sex, age, diabetes duration, clinical variables, and previous HH into account.RESULTS A total of 2,369 events of HH occurred among 1,735 patients with type 1 diabetes of HH during 70,002 patient-years (mean follow-up = 3.7 years). A decrease in incidence rate was observed with calendar time with an 8.4% (4.9–11.7%) annual decrease. Predictors of HH included previous HH, age, diabetes duration, albuminuria, and HbA1c.CONCLUSIONS This study revealed a decreasing trend in incidence of HH in patients with type 1 diabetes. Previous HH, longer diabetes duration, macro-albuminuria, and HbA1c were associated with increased risk of HH in type 1 diabetes, and attention to those factors is warranted in both clinical and public health aspects.

AB - OBJECTIVE This study aimed to examine nationwide incidence trends and predictors of hospitalization for hypoglycemia (HH) in the adult population with type 1 diabetes in Denmark.RESEARCH DESIGN AND METHODS All 17,230 patients with type 1 diabetes aged 16 years and above registered in the Danish Adult Diabetes Database (DADD) from 2006 were followed to 2012 by linkage of registers. Incidence rates of HH were modeled by Poisson regression by calendar time, taking sex, age, diabetes duration, clinical variables, and previous HH into account.RESULTS A total of 2,369 events of HH occurred among 1,735 patients with type 1 diabetes of HH during 70,002 patient-years (mean follow-up = 3.7 years). A decrease in incidence rate was observed with calendar time with an 8.4% (4.9–11.7%) annual decrease. Predictors of HH included previous HH, age, diabetes duration, albuminuria, and HbA1c.CONCLUSIONS This study revealed a decreasing trend in incidence of HH in patients with type 1 diabetes. Previous HH, longer diabetes duration, macro-albuminuria, and HbA1c were associated with increased risk of HH in type 1 diabetes, and attention to those factors is warranted in both clinical and public health aspects.

KW - The Faculty of Health and Medical Sciences

KW - Incidence Trends

KW - Type 1 diabetes

KW - Hypoglycemia

KW - Danish Registers

KW - Poisson regression

KW - Cohort Study

U2 - 10.2337/dc16-0862

DO - 10.2337/dc16-0862

M3 - Journal article

VL - 40

SP - 226

EP - 232

JO - Diabetes Care

JF - Diabetes Care

SN - 0149-5992

IS - 2

ER -

ID: 169705292