Influence of female bodyweight on IVF outcome: a longitudinal multicentre cohort study of 487 infertile couples

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This study investigated the impact of women's body mass index (BMI) on the outcome after consecutive IVF/intracytoplasmic sperm injection cycles in 487 patients initiating treatment with 5-year follow-up. The total number of cycles was 1417. In total 103 (21.1%) were overweight (BMI 25-29.9 kg/m²) and 59 (12.1%) were obese (BMI ≥ 30 kg/m²). Number of initiated cycles/woman (P=0.01), number of cancelled cycles/woman (P <0.01) and the total dose of gonadotrophin used/cycle (P <0.01) rose with increasing BMI. A negative linear association between BMI and the number of retrieved oocytes (B=-0.243, P <0.001) and an inverse U-shaped relationship between BMI and the number of developed embryos was seen, with less embryos available among underweight and obese women (P=0.03). The number with positive serum human chorionic gonadotrophin/cycle decreased significantly with increasing BMI (P <0.01). (20.8% (p="0.040).</div" 15.2% 21.5%. 28.3% age among analysis and birth bmi cycle in independent live live-birth logistic lower men's multiple normal-weight obese of ongoing only p="0.04)." per predictors pregnancy rate regression showed that the versus was were women women's women;>
Original languageEnglish
JournalReproductive BioMedicine Online
Volume23
Issue number4
Pages (from-to)490-499
Number of pages10
ISSN1472-6483
DOIs
Publication statusPublished - 2011

ID: 34082087