Kombinationsbehandling med fluconazol og andre QTc-forlængende lægemidler forlænger QTc- intervallet
Research output: Contribution to journal › Journal article › Research › peer-review
Several drugs have a QTc-prolonging effect and are metabolized by CYP3A4. The combination of QTc-prolonging drugs may act additive of the QTc interval. The risk increases additionally by co-administration of a CYP3A4-inhibiting substrate. This case report describes an incident with QTc prolongation which was probably caused by an interaction induced by a combination of amiodarone, clarithromycin and the CYP3A4-inhibitor fluconazole.
|Journal||Ugeskrift for Laeger|
|Publication status||Published - 5 Oct 2015|
- English Abstract, Journal Article