Prolonged perceived stress and saliva cortisol in a large cohort of Danish public service employees: cross-sectional and longitudinal associations

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Prolonged perceived stress and saliva cortisol in a large cohort of Danish public service employees : cross-sectional and longitudinal associations. / Mikkelsen, Sigurd; Forman, Julie Lyng; Fink, Samuel; Vammen, Marianne Agergaard; Thomsen, Jane Frølund; Grynderup, Matias Brødsgaard; Hansen, Åse Marie; Kaerlev, Linda; Kolstad, Henrik Albert; Rugulies, Reiner; Bonde, Jens Peter.

In: International Archives of Occupational and Environmental Health, Vol. 90, No. 8, 11.2017, p. 835–848.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Mikkelsen, S, Forman, JL, Fink, S, Vammen, MA, Thomsen, JF, Grynderup, MB, Hansen, ÅM, Kaerlev, L, Kolstad, HA, Rugulies, R & Bonde, JP 2017, 'Prolonged perceived stress and saliva cortisol in a large cohort of Danish public service employees: cross-sectional and longitudinal associations', International Archives of Occupational and Environmental Health, vol. 90, no. 8, pp. 835–848. https://doi.org/10.1007/s00420-017-1241-z

APA

Mikkelsen, S., Forman, J. L., Fink, S., Vammen, M. A., Thomsen, J. F., Grynderup, M. B., ... Bonde, J. P. (2017). Prolonged perceived stress and saliva cortisol in a large cohort of Danish public service employees: cross-sectional and longitudinal associations. International Archives of Occupational and Environmental Health, 90(8), 835–848. https://doi.org/10.1007/s00420-017-1241-z

Vancouver

Mikkelsen S, Forman JL, Fink S, Vammen MA, Thomsen JF, Grynderup MB et al. Prolonged perceived stress and saliva cortisol in a large cohort of Danish public service employees: cross-sectional and longitudinal associations. International Archives of Occupational and Environmental Health. 2017 Nov;90(8):835–848. https://doi.org/10.1007/s00420-017-1241-z

Author

Mikkelsen, Sigurd ; Forman, Julie Lyng ; Fink, Samuel ; Vammen, Marianne Agergaard ; Thomsen, Jane Frølund ; Grynderup, Matias Brødsgaard ; Hansen, Åse Marie ; Kaerlev, Linda ; Kolstad, Henrik Albert ; Rugulies, Reiner ; Bonde, Jens Peter. / Prolonged perceived stress and saliva cortisol in a large cohort of Danish public service employees : cross-sectional and longitudinal associations. In: International Archives of Occupational and Environmental Health. 2017 ; Vol. 90, No. 8. pp. 835–848.

Bibtex

@article{c7af82d90d9f4c5c93004b65f225b2bf,
title = "Prolonged perceived stress and saliva cortisol in a large cohort of Danish public service employees: cross-sectional and longitudinal associations",
abstract = "PURPOSE: It is well known that acute stress can lead to a transient increase in cortisol secretion, but the effects of prolonged stress on cortisol secretion are uncertain. This study examines the cross-sectional and longitudinal associations between prolonged perceived stress and salivary cortisol.METHODS: In 2007, 4467 Danish public service employees participated in a study of stress and mental health, and 3217 participated in a follow-up in 2009. Perceived stress during the past 4 weeks was assessed by Cohen's four item perceived stress scale. Participants were asked to collect saliva 30 min after awakening and at approximately 20:00 in the evening. The cortisol dependence on perceived stress was examined in regression analyses adjusted for effects of potential confounders. We adjusted for a large variation in saliva sampling times by modelling the time trajectory of cortisol concentrations in the morning and in the evening and examined if they were influenced by perceived stress.RESULTS: Perceived stress had no statistically significant effects on the level or time trajectory of morning or evening cortisol, neither cross-sectionally nor longitudinally. The 1 month prevalence of frequently perceived stress was low, approximately 2.5{\%}.CONCLUSION: Our results did not support the hypothesis that prolonged perceived stress is associated with the level or time trajectory of morning or evening salivary cortisol.",
keywords = "Journal Article",
author = "Sigurd Mikkelsen and Forman, {Julie Lyng} and Samuel Fink and Vammen, {Marianne Agergaard} and Thomsen, {Jane Fr{\o}lund} and Grynderup, {Matias Br{\o}dsgaard} and Hansen, {{\AA}se Marie} and Linda Kaerlev and Kolstad, {Henrik Albert} and Reiner Rugulies and Bonde, {Jens Peter}",
year = "2017",
month = "11",
doi = "10.1007/s00420-017-1241-z",
language = "English",
volume = "90",
pages = "835–848",
journal = "International Archives of Occupational and Environmental Health",
issn = "0340-0131",
publisher = "Springer",
number = "8",

}

RIS

TY - JOUR

T1 - Prolonged perceived stress and saliva cortisol in a large cohort of Danish public service employees

T2 - cross-sectional and longitudinal associations

AU - Mikkelsen, Sigurd

AU - Forman, Julie Lyng

AU - Fink, Samuel

AU - Vammen, Marianne Agergaard

AU - Thomsen, Jane Frølund

AU - Grynderup, Matias Brødsgaard

AU - Hansen, Åse Marie

AU - Kaerlev, Linda

AU - Kolstad, Henrik Albert

AU - Rugulies, Reiner

AU - Bonde, Jens Peter

PY - 2017/11

Y1 - 2017/11

N2 - PURPOSE: It is well known that acute stress can lead to a transient increase in cortisol secretion, but the effects of prolonged stress on cortisol secretion are uncertain. This study examines the cross-sectional and longitudinal associations between prolonged perceived stress and salivary cortisol.METHODS: In 2007, 4467 Danish public service employees participated in a study of stress and mental health, and 3217 participated in a follow-up in 2009. Perceived stress during the past 4 weeks was assessed by Cohen's four item perceived stress scale. Participants were asked to collect saliva 30 min after awakening and at approximately 20:00 in the evening. The cortisol dependence on perceived stress was examined in regression analyses adjusted for effects of potential confounders. We adjusted for a large variation in saliva sampling times by modelling the time trajectory of cortisol concentrations in the morning and in the evening and examined if they were influenced by perceived stress.RESULTS: Perceived stress had no statistically significant effects on the level or time trajectory of morning or evening cortisol, neither cross-sectionally nor longitudinally. The 1 month prevalence of frequently perceived stress was low, approximately 2.5%.CONCLUSION: Our results did not support the hypothesis that prolonged perceived stress is associated with the level or time trajectory of morning or evening salivary cortisol.

AB - PURPOSE: It is well known that acute stress can lead to a transient increase in cortisol secretion, but the effects of prolonged stress on cortisol secretion are uncertain. This study examines the cross-sectional and longitudinal associations between prolonged perceived stress and salivary cortisol.METHODS: In 2007, 4467 Danish public service employees participated in a study of stress and mental health, and 3217 participated in a follow-up in 2009. Perceived stress during the past 4 weeks was assessed by Cohen's four item perceived stress scale. Participants were asked to collect saliva 30 min after awakening and at approximately 20:00 in the evening. The cortisol dependence on perceived stress was examined in regression analyses adjusted for effects of potential confounders. We adjusted for a large variation in saliva sampling times by modelling the time trajectory of cortisol concentrations in the morning and in the evening and examined if they were influenced by perceived stress.RESULTS: Perceived stress had no statistically significant effects on the level or time trajectory of morning or evening cortisol, neither cross-sectionally nor longitudinally. The 1 month prevalence of frequently perceived stress was low, approximately 2.5%.CONCLUSION: Our results did not support the hypothesis that prolonged perceived stress is associated with the level or time trajectory of morning or evening salivary cortisol.

KW - Journal Article

U2 - 10.1007/s00420-017-1241-z

DO - 10.1007/s00420-017-1241-z

M3 - Journal article

VL - 90

SP - 835

EP - 848

JO - International Archives of Occupational and Environmental Health

JF - International Archives of Occupational and Environmental Health

SN - 0340-0131

IS - 8

ER -

ID: 183246706