Determinants of serum tryptase in a general population: the relationship of serum tryptase to obesity and asthma

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Recent studies indicate that mast cells are more abundant in the obese state. Total serum tryptase (ST) is a marker of mast cell numbers or activity. Since obesity and asthma have been consistently linked in epidemiological studies, a possible higher mast cell activity in obesity could be a factor between the two conditions. The aim of this study was to investigate determinants of ST and whether a potential association between obesity and allergic respiratory disease would be influenced by levels of ST in obese persons.
Original languageEnglish
JournalInternational Archives of Allergy and Immunology
Issue number2
Pages (from-to)151-8
Number of pages8
Publication statusPublished - 2012

ID: 40217515