Determinants of serum tryptase in a general population: the relationship of serum tryptase to obesity and asthma

Research output: Contribution to journalJournal articleResearchpeer-review

R V Fenger, A Linneberg, C Vidal, L Vizcaino, Lise-Lotte Husemoen, Mette Aadahl, A Gonzalez-Quintela

Recent studies indicate that mast cells are more abundant in the obese state. Total serum tryptase (ST) is a marker of mast cell numbers or activity. Since obesity and asthma have been consistently linked in epidemiological studies, a possible higher mast cell activity in obesity could be a factor between the two conditions. The aim of this study was to investigate determinants of ST and whether a potential association between obesity and allergic respiratory disease would be influenced by levels of ST in obese persons.
Original languageEnglish
JournalInternational Archives of Allergy and Immunology
Volume157
Issue number2
Pages (from-to)151-8
Number of pages8
ISSN1018-2438
DOIs
Publication statusPublished - 2012

ID: 40217515