Increased muscle interstitial levels of inflammatory cytokines in polymyalgia rheumatica

Research output: Contribution to journalJournal articleResearchpeer-review

Frederik Kreiner, Henning Langberg, Henrik Galbo

Polymyalgia rheumatica (PMR) is characterized by aching of the proximal muscles and increased blood levels of markers of inflammation. Despite the muscle complaints, the current view is that symptoms are caused by inflammation in synovial structures. The purpose of this study was to elucidate the disease mechanisms in symptomatic muscles by measuring interstitial levels of cytokines before and after prednisolone treatment.
Original languageEnglish
JournalArthritis & Rheumatism
Volume62
Issue number12
Pages (from-to)3768-75
Number of pages8
ISSN0004-3591
DOIs
Publication statusPublished - 2010

    Research areas

  • Aged, Aged, 80 and over, C-Reactive Protein, Chemokine CCL2, Cytokines, Female, Glucocorticoids, Humans, Interleukin-1alpha, Interleukin-1beta, Interleukin-6, Interleukin-8, Male, Middle Aged, Muscle, Skeletal, Polymyalgia Rheumatica, Prednisolone, Tumor Necrosis Factor-alpha

ID: 38363830